Clinical trials: Spinal Paralysis
Spina Bifida, Cerebral Palsy
Grand Valley State University (GVSU) Skills on Wheels
Manual wheelchairs (MWCs) are widely used by children with physical disabilities, yet many of these children are unable to use their wheelchair independently. Instead, they depend on others to push them.
- Conditions
- Spina Bifida, Cerebral Palsy, Genetic Disease, Spinal Cord Injuries
- Trial name
- NCT05339932
- Testing
- Manual Wheelchair Skills Training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Grand Valley State University
Nerve Transfer
Nerve Transfers for Restoration of Hand Function in Cervical Spinal Cord Injury: Effects and Influencing Factors
The goal of this observational study is to learn about influencing factors on the clinical outcomes of nerve transfers used to restore hand function in patients with cervical spinal cord injury (CSCI).
- Trial name
- NCT06596629
- Where
- Netherlands
- Volunteers
- 19 people
- Sponsor
- Roessingh Research and Development
Spinal Cord Injury, Tetraplegia
Abdominal Functional Electrical Stimulation (AFES) to Assist Ventilator Weaning in Tetraplegia
Compromised respiratory function as a result of tetraplegia leads to many tetraplegics requiring mechanical ventilation during the acute phase of injury.
- Trial name
- NCT02200393
- Testing
- Abdominal FES
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Glasgow
Cerebral Palsy
Noninvasive Spinal Neuromodulation Enables Locomotor Recovery in Individuals With Cerebral Palsy
Assessing the effects of noninvasive spinal cord neuromodulation on improving function in individuals with cerebral palsy
- Trial name
- NCT04882592
- Testing
- SCiP
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SpineX Inc.
Amyotrophic Lateral Sclerosis, Stroke
Telehealth Implementation of Brain-Computer Interface
Determine if Telehealth intervention can allow/empower a caregiver (who is untrained) to effectively implement and utilize a Brain-Computer Interface for communication with a participant who is "Locked in" following progression…
- Trial name
- NCT05951556
- Testing
- Use of BCI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebral Palsy, Spina Bifida
The Impact of Participation on Body Functions Among Youth With Physical Disabilities
Youth with physical disabilities experience greater limitations to participation in community- based activities than do their average-developing peers, which can result in poor health outcomes.
- Conditions
- Cerebral Palsy, Spina Bifida, Musculoskeletal Disorders
- Trial name
- NCT04288453
- Testing
- Engagement in a 8-week community-based activity program
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- McGill University
Balanced; Rearrangement, Respiratory Function Test
The Effect of Lycra Garment on Spastic Diplegic Cerebral Palsy Individuals With Scoliosis
The primary aim of this study was to investigate the effects of lycra clothing on balance and respiratory functions in individuals with cerebral palsy with scoliosis, and the secondary aim was to investigate the effects of lycra…
- Trial name
- NCT06295991
- Testing
- Lycra garment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Cerebral Palsy, Spina Bifida
A Peer E-mentoring Intervention to Improve Employment
Despite the strong business case of hiring people with disabilities, a significant proportion of youth with disabilities leave high school and neither work nor continue their education and are unprepared to meet the demands of a…
- Conditions
- Cerebral Palsy, Spina Bifida, Juvenile Arthritis, Spinal Cord Injury
- Trial name
- NCT02522507
- Testing
- Empowering youth towards employment
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Metastatic Spinal Tumors, Spinal Cord Compression
Postoperative Neurological Recovery and Risk Factor Analysis in Patients With Paralysis Due to Spinal Metastases
Metastatic spinal tumors represent a common and devastating complication in patients with advanced solid malignancies. Up to 40% of cancer patients may develop spinal metastases during the course of their disease, often resulting…
- Conditions
- Metastatic Spinal Tumors, Spinal Cord Compression, Paralysis, Neurological Deficits
- Trial name
- NCT07527728
- Volunteers
- 150 people
- Sponsor
- Shanghai Changzheng Hospital
Incomplete Spinal Cord Injury, Muscular Dystrophy
Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
Background: Cerebral palsy (CP) is the most common motor disorder in children. CP often causes crouch gait, an abnormal way of walking. Knee crouch has many causes, so no single device or approach works best for everybody.
- Conditions
- Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
- Trial name
- NCT01961557
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cerebral Palsy
Neuromodulation of the Cortex and Spinal Cord
Specific Aim 1: To further quantify the difference in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence of persons with CP.
- Trial name
- NCT06586437
- Testing
- Clinical Assessments, Brain-Spinal Cord fMRI, Hoffmann Reflex Assessments
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Idiopathic Toe Walking, Cerebral Palsy
The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk.
- Conditions
- Idiopathic Toe Walking, Cerebral Palsy, Hereditary Spastic Paraparesis, Traumatic Brain Injury
- Trial name
- Plantaris Sx (NCT07090057)
- Testing
- Tendoachilles (TA) lengthening or gastrocnemius (GN) recession, then Plantaris tenotomy, Plantaris tenotomy, then Tendoachilles (TA) lengthening or gastrocnemius (GN) recession
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Cerebral Palsy, Spastic
Influence of the Spinal Manipulation on Muscle Spasticity and Manual Dexterity in Cerebral Palsy.
The aim of the study is to evaluate a short term influence of the Spinal Manipulation (SM) on the wrist muscles spasticity and manual dexterity in children with spastic Cerebral Palsy.
- Trial name
- SpiManCP (NCT03005938)
- Testing
- Spinal manipulation, Imitation of the spinal manipulation
- Where
- Ukraine
- Volunteers
- 85 people
- Sponsor
- International Clinic of Rehabilitation, Ukraine
Kyphosis
Correction for Kyphotic Posture for Improving Balance in Cerebral Palsy
Children with spastic diplegia are at an increased risk of spinal deformities. The most common types of these spinal deformities are scoliosis and kyphosis.
- Trial name
- NCT05063175
- Testing
- Conventional Physical Therapy Protocol, TheraTog orthotic undergarment with its strapping system
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Child With Cancer, Muscular Atrophy, Spinal
A BHI to Increase Hope Level and Stress Level of Parents With a CMC
Being a parent of a child with medical complexity (CMC) poses an enormous stress because these CMC have a multisystem disease, a severe neurologic condition or cancer which may result in premature death.
- Conditions
- Child With Cancer, Muscular Atrophy, Spinal, Child With Cerebral Palsy, Endocrine System Diseases
- Trial name
- NCT05269693
- Testing
- Brief Hope Intervention
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Spastic Diplegia Cerebral Palsy, Spastic Hemiplegia
Spinal Mobility in Children With Cerebral Palsy: NDT-Bobath and Exergaming
The purpose of this study is to evaluate changes in spinal mobility in the cervical, thoracic, and lumbar regions in children with cerebral palsy aged 10-15 years.
- Trial name
- NCT07421505
- Testing
- NDT-Bobath Therapy, Sitting Exergaming, Standing Exergaming
- Where
- 2 sites in Poland
- Volunteers
- 42 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Cerebral Palsy, Neuromuscular Scoliosis
Seating System for Scoliosis in Non-ambulatory Children With Cerebral Palsy: A Pilot Randomized Controlled Trial
The effect of a modular seating system on coronal and sagittal balance of the spine and pelvic obliquity in children with non-ambulatory (Gross Motor Function Classification System Level IV-V) and scoliosis The hypothesis in our…
- Trial name
- NCT03862625
- Testing
- a modular adaptive seating system, home exercise program for scoliosis
- Volunteers
- 30 people
- Sponsor
- Merve Damla Korkmaz
Cerebral Palsy (CP), Spastic Paraplegia
Retrospective Study on the WalkOn AFO in Children or Teenagers With Neurological Pathologies
The goal of this observational study is to assess the interest of prefabricated carbon fiber ankle foot orthoses (AFO) in children and teenagers with central or peripheral neurological pathologies.
- Conditions
- Cerebral Palsy (CP), Spastic Paraplegia, Spinal Cord Injuries (SCI), Spina Bifida
- Trial name
- NCT06740006
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Otto Bock France SNC
Spinal Cord Injuries, Spina Bifida
Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.
The goal of this clinical trial is to learn about how a participation-based intervention builds capacity of youth with physical disabilities to pursue activities of their choice in the community.
- Conditions
- Spinal Cord Injuries, Spina Bifida, Musculoskeletal Disorder, Juvenile Arthritis
- Trial name
- NCT06007885
- Testing
- Pathways and Resources to Engagement and Participation (PREP)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University
Neuromuscular Disorders, Neurodevelopmental Disorders
Efficacy and Usability of the EXPLORER Exoskeleton in Children With Neurodevelopmental Disorders in Natural Environments
Neurodevelopmental disorders often lead to abnormal development of the Central Nervous System (CNS), frequently causing motor dysfunctions such as an inability to stand and walk.
- Trial name
- NCT06765070
- Testing
- EXPLORER
- Where
- 6 sites in Spain
- Volunteers
- 15 people
- Sponsor
- MarsiBionics