Clinical trials: Spinal Surgery
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Scoliosis
Scoliosis and Quality of Life of Adolescents
Around the scoliosis surgery, the pain (pre or post operative, physical, psychological, fantasy or real) is a major concern for adolescents and their families.
- Trial name
- SQUAD (NCT02890654)
- Testing
- First time measure, Second time measure, Third time measure
- Where
- France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Toulouse
Brain and Central Nervous System Tumors
Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00028795
- Testing
- temozolomide, adjuvant therapy, radiation therapy
- Where
- 230 sites in United States, Australia and 5 more
- Volunteers
- 170 people
- Sponsor
- Children's Oncology Group
Scoliosis
Effect of Early Morphine Administration on the Development of Acute Opioid Tolerance During Pediatric Scoliosis Surgery
The purpose of this study is to examine if morphine administered by bolus before initiating Remifentanil by infusion decreases the incidence of acute post-operative opioid tolerance as demonstrated by decreased post - operative…
- Trial name
- NCT00737997
- Testing
- Morphine, Saline
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Scoliosis Idiopathic, Scoliosis; Adolescence
Postoperative Rehabilitation or Mobilization After Scoliosis Surgery
Scoliosis surgery is a major surgery associated with postoperative pain, loss of physical function and pulmonary dysfunction in adolescent idiopathic scoliosis patients (AIS).Despite the advanced, various medical treatment…
- Trial name
- NCT04403152
- Testing
- Post-operative rehabilitation, Post-operative mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Scoliosis Correction, Iron Deficiency
IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study
Adolescents and young adults undergoing spinal fusion surgery for the correction of scoliosis and other spinal deformity are at high risk of perioperative iron deficiency and anemia, yet the means and evidence for optimizing iron…
- Conditions
- Scoliosis Correction, Iron Deficiency, Transfusion Blood, Surgery Complications
- Trial name
- IV-KIDS (NCT07217873)
- Testing
- Ferric carboxymaltose IV
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Columbia University
Spinal Diseases
Observational Clinical Study to Plan, Position and Check Instrument Placement for Spine Surgery Interventions
There is a clear need in spine surgery to place pedicle screws in the right place in the spine with good accuracy to avoid damage to important structures (spinal cord, nerve roots or vertebral arteries).
- Trial name
- NCT03015142
- Testing
- New image-guidance software
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Kidney Calculi
Effect of Anesthesia Type on Surgeon Workload During Endoscopic Kidney Stone Surgery
This prospective observational study aims to evaluate the association between anesthesia type and surgeon-perceived workload and surgical ergonomics in adult patients undergoing flexible ureteroscopy and retrograde intrarenal…
- Trial name
- RIRS-ERG (NCT07763600)
- Testing
- General Anesthesia (GA), Spinal Anesthesia (SA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Malatya Governor Research Hospital
Hypertrophic Pyloric Stenosis, Spinal Anesthesia
Spinal Anesthesia and General Anesthesia for Pyloromyotomy - Surgical Outcomes a Comparison Retrospective Study
Background: The purpose of this retrospective study is to evaluate surgical outcomes of pyloromyotomy in infants performed under spinal anesthesia compares to general anesthesia.
- Conditions
- Hypertrophic Pyloric Stenosis, Spinal Anesthesia, General Anesthesia
- Trial name
- NCT03095144
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Spinal Deformity, Hemothorax Postoperative
Hemothorax Caused by Posterior Correction Surgery for Spinal Deformity
Owing to the development of instruments and surgical techniques, the number of spinal deformity correction surgeries has increased significantly.
- Trial name
- NCT05579834
- Testing
- posterior correction surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Gazi University
Surgical Site Infection (SSI), Spine Diseases
Efficacy of Intrawound Vancomycin in Spine Surgery
"This multicenter, prospective, time-cluster randomized controlled trial with blinded endpoint assessment (PROBE design) evaluated the efficacy of intrawound vancomycin powder (2 g) in preventing surgical site infections (SSI)…
- Trial name
- NCT07866157
- Testing
- vancomycin, Standard surgical closure
- Where
- Egypt
- Volunteers
- 416 people
- Sponsor
- Ain Shams University
Scoliosis
Surgical Guide for Thoracic Pedicle Screw Instrumentation in Scoliosis Correction Surgery
Surgical Guide for Thoracic Pedicle Screw Instrumentation in Scoliosis Correction Surgery
- Trial name
- NCT04753905
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Pain Following Decompressive Lumbar Spinal Surgery
The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal Surgery
The primary aim of this study is to assess the impact of intrathecal morphine on post-operative pain following instrumented fusion for degenerative lumbar spine disease.
- Trial name
- ITMP (NCT01053039)
- Testing
- Intrathecal Morphine, Intrathecal Saline
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Pain, Postoperative, Excavatum, Pectus
Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
This will be a prospective observational study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain…
- Conditions
- Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
- Trial name
- NCT04031716
- Testing
- Meditation
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Scoliosis
Pharmacokinetics of Aminocaproic Acid in Scoliosis Surgery
This study will evaluate the pharmacokinetics of antifibrinolytic drug epsilon-aminocaproic acid (EACA) in children undergoing Posterior spinal fusion surgery (PSF) at The Children's Hospital of Philadelphia (CHOP) who receive…
- Trial name
- NCT01408823
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Wounds
The Use of Dermabond Versus Standard Staple for Wound Closure in Children With Neuromuscular Scoliosis Undergoing Spinal Deformity Correction Surgery
This is a prospective, Phase II (hypothesis generating) randomized pilot study investigating the efficacy of using Dermabond as a method of final wound closure as compared to the standard staple method in children with…
- Trial name
- NCT01135940
- Testing
- 2-octylcyanoacrylate (Dermabond) closure, Standard staple closure
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Scoliosis
The Idiopathic Scoliosis and Its Treatment (Orthopaedic and Surgery): Effect of the Severity, the Orthosis and the Arthrodesis on the Gait
The purposes of this study were as follows: 1) to compare locomotion parameters (kinematic, EMG, mechanical work and energy cost changes during walking in able-bodied subjects and AIS patients,2) to evaluate the effects of the…
- Trial name
- scoliosis (NCT00842218)
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Chiari Malformation Type I, Tonsillectomy
PFDD Versus PFDRT in Chiari Decompression Surgery
The purpose of this study is to determine whether a posterior fossa decompression and duraplasty with or without tonsil manipulation results in better patient outcomes with fewer complications and improved quality of life in…
- Trial name
- NCT06079125
- Testing
- Posterior fossa decompression with duraplasty, PFDD with tonsillar resection/reduction
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xuanwu Hospital, Beijing
Pain, Postoperative, Pain
Improved Rehabilitation After Spinal Surgery in Adolescents
Impact of the OFA technique on postoperative recovery from adolescent spine surgery and the incidence of chronic postoperative pain.
- Conditions
- Pain, Postoperative, Pain, Scoliosis, Spinal Fusion
- Trial name
- NCT04183049
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Pediatrics, Spinal Aneshtesia
A Comparative Study Between Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia in Children Undergoing Elective Infra-Umbilical Surgeries
This prospective randomized double-blinded controlled trial will include 60 pediatric patients aged 1 - 6 years old, both sexes, with American society of anesthesiologists (I and II) and undergoing elective infra-umbilical…
- Conditions
- Pediatrics, Spinal Aneshtesia, Infraumbilical Surgeries
- Trial name
- NCT07035184
- Testing
- Spinal Anesthesia with Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University