Clinical trials: Spinal Surgery
Cerebral Palsy
Minimizing Complications in Scoliosis Surgery in Children With Cerebral Palsy
Background: Posterior spinal fusion (PSF) in children with cerebral palsy (CP) carries a high risk of complications and mortality.
- Trial name
- NCT02547090
- Testing
- The use of two attending surgeons during posterior spinal fusion
- Volunteers
- 50 people
- Sponsor
- Phoenix Children's Hospital
Symptomatic Epidural Hematoma After Cervical Spine Surgery
Incidence and Risk Factors of Symptomatic Epidural Hematoma After Cervical Spine Surgery
The incidence and correlation of symptomatic epidural hematomas after cervical spine surgery was reviewed and analyzed, then it will provide reference to avoid the occurrence of this complication for the future clinical work.
- Trial name
- NCT05190276
- Volunteers
- 129 people
- Sponsor
- Peking University Third Hospital
Scoliosis, Regional Anesthesia
Erector Spine Plane (ESP) Block for Analgesia in Pediatric Scoliosis Surgery
Postoperative pain after scoliosis correction surgery is severe and usually requires long-term intravenous opioid therapy. Local anesthetic options are limited and include intrathecal opioids and epidural analgesia.
- Conditions
- Scoliosis, Regional Anesthesia, Pediatric Anesthesia, Orthopedic Disorder of Spine
- Trial name
- NCT05944393
- Testing
- Ropivacaine 0.2% Injectable Solution, Normal saline 0.9% Injectable Solution
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Poznan University of Medical Sciences
Scoliosis
The Idiopathic Scoliosis and Its Treatment (Orthopaedic and Surgery): Effect of the Severity, the Orthosis and the Arthrodesis on the Gait
The purposes of this study were as follows: 1) to compare locomotion parameters (kinematic, EMG, mechanical work and energy cost changes during walking in able-bodied subjects and AIS patients,2) to evaluate the effects of the…
- Trial name
- scoliosis (NCT00842218)
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) Gold Standard for Blood Loss
The purpose of this study is to establish a benchmark for measuring blood loss by directly measuring the change in red cell volume before and after surgery and to compare established blood loss estimators to this benchmark in…
- Trial name
- NCT03990376
- Testing
- Radioisotope I-131-labeled albumin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Spinal Tumors
Long-Term Patient Reported Outcomes Following Surgery for Spinal Intradural Tumours
The objective of this study is to identify the long-term impact of PSIDT tumours and their treatment on patient HRQoL for those managed at the Walton Centre NHS Foundation Trust (WCFT), which provides tertiary care to a catchment…
- Trial name
- PRO-SSIT (NCT07849868)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Walton Centre NHS Foundation Trust
Pediatrics, Spinal Aneshtesia
A Comparative Study Between Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia in Children Undergoing Elective Infra-Umbilical Surgeries
This prospective randomized double-blinded controlled trial will include 60 pediatric patients aged 1 - 6 years old, both sexes, with American society of anesthesiologists (I and II) and undergoing elective infra-umbilical…
- Conditions
- Pediatrics, Spinal Aneshtesia, Infraumbilical Surgeries
- Trial name
- NCT07035184
- Testing
- Spinal Anesthesia with Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Thoracic Surgery, Scoliosis; Adolescence
Chronic Pain After Scoliosis and Thoracic Surgery in Children
The aim of this epidemiologic prospective study is to determine the prevalence of CPSP defined as pain occurring 4 months after scoliosis and thoracic surgery and rated > 3 on a 10 point visual analogue scale or FLACC scale, in…
- Conditions
- Thoracic Surgery, Scoliosis; Adolescence, Pediatric ALL, Chronic Pain
- Trial name
- PEDIACHROII (NCT02995525)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Bordeaux
Scoliosis; Adolescence, Spine Fusion
Evaluation of Surgical Treatment of Idiopathic Scoliosis With Vertebral Body Tethering Versus Posterior Spinal Fusion.
The aim of this study is to evaluate the short, medium and long-term efficacy and safety of vertebral body tethering, based on the results obtained at 3-5 months of follow-up, exploring not only the ability to correct scoliosis…
- Trial name
- NCT07450326
- Testing
- gait analysis
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Istituto Ortopedico Rizzoli
to See Whether Negative Pressure Wound Therapy Decreases Wound Infections.
Negative Pressure Wound Therapy - A Multi-Centered Randomized Control Trial
Children with neuromuscular disorders such as cerebral palsy, children with kyphosis and post-traumatic scoliosis have higher infection rates after scoliosis surgery than healthy children who undergo scoliosis surgery.
- Trial name
- NPWT (NCT02790385)
- Testing
- Negative Pressure Wound Therapy, Standard Gauze Treatment
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postoperative Pain, Spinal Fusion
Postoperative Pain Control Using Local Wound Infiltration in Adolescent Idiopathic Surgery
Non-opioid methods of pain management following posterior spinal fusion (PSF) have become increasingly popular given the rise of opioid abuse and opioid-related deaths.
- Trial name
- NCT04730531
- Testing
- Local infiltration with 0.25% bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Tethered Cord
Effects of Anesthetic Infusion on the Amplitude of Motor Evoked Potential in Pediatrics Undergoing Tethered Spinal Cord Surgeries
The tethered spinal cord is a common pathology in pediatric neurosurgery. Intraoperative neurophysiologic monitoring (IOM) has gained popularity over the past two decades as a clinical discipline that uses neurophysiologic…
- Trial name
- NCT05591001
- Testing
- ketamine and dexmeditomidine combination, Propofol
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis
The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery
This study is being done to better understand the efficacy of an erector spinae plane block (ESPB) in pain management for children with Adolescent Idiopathic Scoliosis or Neuromuscular Scoliosis undergoing Posterior Spinal Fusion…
- Conditions
- Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
- Trial name
- ESPB (NCT07561827)
- Testing
- Ropivacaine Hydrocloride
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Francisco
Lumbar Spinal Stenosis, Surgery
Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis
Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment.
- Trial name
- NCT04254757
- Testing
- Two different treatment
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Juvenile; Scoliosis, Scoliosis Idiopathic
Studying Melatonin and Recovery in Teens
The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgerySMART (NCT06093477)
- Testing
- Fast-Dissolve Melatonin Pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Degenerative Lumbar Spinal Stenosis, Lumbarsacral Orthosis
Is Postoperative Bracing Necessary After Spine Surgery for Degenerative Conditions
This study was started from Oct. 2015. This study aimed to evaluate the outcome of bracing following transforaminal lumbar interbody fusion (TLIF) in patients with degenerative lumbar spine diseases.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Lumbarsacral Orthosis, Transforaminal Lumbar Interbody Fusion
- Trial name
- NCT03560401
- Testing
- Knight-Taylor [chairback] brace
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Lumbar Disc Degeneration, Surgical Procedure, Unspecified
Evaluation of Topical and Intravenous Tranexamic Acid in Surgical Treatment of Lumbar Degenerative Disease
Evaluation of Topical and Intravenous Tranexamic Acid in Surgical Treatment of Lumbar Degenerative Disease
- Trial name
- NCT02496364
- Testing
- Observational
- Sponsor
- Vinicius Magno da Rocha, MD, MSc
Thoracic Insufficiency Syndrome, TIS
Tools for the Objective Clinical Assessment of Pediatric Spinal Deformity
This project seeks to develop a standardized technique for simultaneous capturing bi-planar images of patients against a standard background with a grid that can be used later for the quantitative determination of global balance…
- Trial name
- NCT00585234
- Testing
- Digital Photography
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Anesthesia, Anorectal Surgery
Spinal Anesthesia Versus General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
Anorectal surgeries are of the commonest elective surgeries that are performed worldwide under different types of anaesthesia. The aim of this prospective interventional study was to compare the use of general anaesthesia (GA)…
- Trial name
- NCT04214977
- Testing
- Spinal Anesthesia for Anorectal Surgeries in Prone Position, General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
- Where
- Jordan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Pain
Preemptive Genotyping and Pain Management
The purpose of this study is to see if testing for genes related to pain and pain management before surgery affects how patients are treated for pain after surgery.
- Trial name
- NCT01813695
- Testing
- Preemptive genotyping in medical record, Genotyping not included in electronic medical record
- Where
- United States
- Volunteers
- 576 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati