Clinical trials: Spine Fusion
Degenerative Disc Disease in Cervical Spine, Stenosis Cervical Spine
PMCF Study Fortilink-SC
This study is setup to be able to gather information on the safety and performance of the Fortilink-SC Ti cage of Paradigm Spine GmbH, up to one year after the surgery.
- Trial name
- NCT07834749
- Testing
- Cervical interbody fusion surgery (standalone)
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- BAAT Medical Products B.V.
Scoliosis; Adolescence, Degenerative Disc Disease
Personalized Spine Study Group Registry
As a registry, the primary objective of the study is a data collection initiative. The study will collect clinical and radiographic outcomes of patients implanted with Medicrea's PSR.
- Conditions
- Scoliosis; Adolescence, Degenerative Disc Disease, Spinal Fusion, Kyphoscoliosis
- Trial name
- NCT03843476
- Testing
- Patient Specific Rod
- Sponsor
- Medicrea, USA Corp.
Lumbar Spine Degeneration
Development of a Patient-reported Outcome Instrument for Patients With Lumbar Degenerative Disease After Lumbar Fusion
The commonly used scales (ODI+JOA-29+VAS) lack the assessment of lumbar stiffness, and there is no scale for evaluating lumbar stiffness in China.Based on the Delphi method and the analytic hierarchy process, this study will…
- Trial name
- DPROIPLDDALF (NCT04781517)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
PPAP, Spine Fusion
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative…
- Trial name
- PPAP Spine (NCT05367609)
- Testing
- Preoperative Genotyping
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Senthil Sadhasivam
Spinal Fusion
Safety and Efficacy of Subdermal Betadine During Posterior Spinal Fusion
Bacterial in the subdermal layer of the skin, such as in hair follicles and sweat glands, may contaminate surgical wounds. The goal of this study is to learn about povidone-iodine and its ability to prevent infections…
- Trial name
- NCT06744907
- Testing
- 10% Povidone-Iodine Arm, Saline Arm
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Akron Children's Hospital
Lumbar Spine Instability
MRI Analysis of Glycosaminoglycan Modifications Inside the Intervertebral Disk After Distraction and Posterior Fusion
Degenerative disc disease (DDD) is the primary cause of low back pain. The most important factor in the development of DDD is the vertical load force on the disc, increasing the hydrostatic pressure and facilitating discs…
- Trial name
- NCT02815696
- Testing
- Magnetic Resonance Imaging
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Brugmann University Hospital
Spinal Fusion, Spinal Stenosis
Spine Registration Using 3D Scanning
The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.
- Conditions
- Spinal Fusion, Spinal Stenosis, Scoliosis, Spondylolisthesis
- Trial name
- NCT05195580
- Testing
- Optical 3D Scanner
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Advanced Scanners Inc.
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Scoliosis; Adolescence, Spine Fusion
Evaluation of Surgical Treatment of Idiopathic Scoliosis With Vertebral Body Tethering Versus Posterior Spinal Fusion.
The aim of this study is to evaluate the short, medium and long-term efficacy and safety of vertebral body tethering, based on the results obtained at 3-5 months of follow-up, exploring not only the ability to correct scoliosis…
- Trial name
- NCT07450326
- Testing
- gait analysis
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Istituto Ortopedico Rizzoli
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
Degenerative Lumbar Spinal Stenosis, Lumbarsacral Orthosis
Is Postoperative Bracing Necessary After Spine Surgery for Degenerative Conditions
This study was started from Oct. 2015. This study aimed to evaluate the outcome of bracing following transforaminal lumbar interbody fusion (TLIF) in patients with degenerative lumbar spine diseases.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Lumbarsacral Orthosis, Transforaminal Lumbar Interbody Fusion
- Trial name
- NCT03560401
- Testing
- Knight-Taylor [chairback] brace
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Idiopathic Scoliosis
Evaluation of Analgesia for Spine Fusion Elective Surgery in Children
The multicenter PRECISE Analgesia (Prospective Randomized Evaluation of Analgesia for Idiopathic Scoliosis Spine Fusion Elective Surgery in Children) trials will a) implement and investigate the efficacy and safety of multidose…
- Trial name
- PRECISE (NCT06626503)
- Testing
- Methadone based ERAS, Non-methadone based group
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Senthil Sadhasivam
Patients Undergoing Spine Surgery, Scoliosis
Galeazzi Spine Surgery RegistryGaleazzi Spine Registry: Prospective Study for Clinical Monitoring
The SPINEREG study is a prospective observational registry. Eligible patients are subjects undergoing spine surgery at the participating institutions.
- Conditions
- Patients Undergoing Spine Surgery, Scoliosis, Disc Disease, Disc Injury
- Trial name
- SPINEREG (NCT03644407)
- Testing
- Spine Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Scoliosis
Evaluate Initial Safety of the HemiBridge™ System in Guided Spinal Growth Treatment of Progressive Idiopathic Scoliosis
The purpose of this clinical trial is to study a new method of treatment for patients who are diagnosed with idiopathic scoliosis and have abnormal and increasing curvature of the spine.
- Trial name
- NCT01465295
- Testing
- Mechanical hemiepiphysiodesis using the HemiBridge System
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- SpineForm LLC
Spinal Fusion
Spinal Fusions Steroid Study
Current efforts to improve pain alleviation focus on non-opioid pharmaceuticals. Intravenous perioperative corticosteroid administration has been suggested as an alternative method for post-operative pain control.
- Trial name
- SFSS (NCT05287035)
- Testing
- Dexamethasone injection, Saline injection
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Texas at Austin
Scoliosis, Spinal Fusion
Is Pleth Variability Index (PVI) a Surrogate for Pulse Pressure Variations (PPV) in Pediatric Spine Fusion (SF) Surgery?
Spine fusion is an involved procedure during which patients are at risk for significant intra-operative blood loss.This study will compare 2 ways of determining fluid status and response to fluid administration.
- Trial name
- NCT00994656
- Testing
- Masimo multi-wavelength pulse co-oximeter
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Children's Hospital of Philadelphia
Spinal Fusion
Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho)
The goal of this observational study is to learn about endothelial damage in major spine surgery, expressed as rise in circulating Syndecan-1.
- Trial name
- GlycOrtho (NCT06119542)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Adolescent Idiopathic Scoliosis
Prospective Study of Motion Preservation Evaluation Below Fusions of the Spine in Adolescent Idiopathic Scoliosis
The purpose of this study is to evaluate the relationship of A) The distal fusion level B) The total length of fusion and the post-operative range of motion in the unfused vertebral segments below the fusion in patients with…
- Trial name
- POM (NCT01661998)
- Where
- 3 sites in United States
- Volunteers
- 273 people
- Sponsor
- Setting Scoliosis Straight Foundation