Clinical trials: Spine Surgery
Spinal Diseases
Observational Clinical Study to Plan, Position and Check Instrument Placement for Spine Surgery Interventions
There is a clear need in spine surgery to place pedicle screws in the right place in the spine with good accuracy to avoid damage to important structures (spinal cord, nerve roots or vertebral arteries).
- Trial name
- NCT03015142
- Testing
- New image-guidance software
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Back Pain, Sciatica
Predictive Value of the Five-repetition Sit-to-stand Test After Lumbar Spine surgerySTS-3 Study.
Sciatica is a disabling condition that affects many people. This condition has an enormous influence on the social functioning of patients.
- Trial name
- 5R-STS-III (NCT04660656)
- Testing
- 5 repetition sit-to-stand test
- Where
- 2 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Bergman Clinics
Spine Fracture
Surgical Treatment of Fractures of the Dorso-lombar Spine
Trauma to the thoracolumbar spine is responsible for potentially serious lesions, most often involving the functional prognosis in the short, medium and long term, and rare The frequency of these traumas is explained by falls…
- Trial name
- NCT06374472
- Testing
- Osteosynthesis
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- Ibn Jazzar Hospital
Scoliosis
Use of Virtual Reality to Reduce Morphine Consumption in Adolescents Undergoing Scoliosis Surgery
The objective is to evaluate the effect of the association of virtual reality sessions with usual management on the cumulative consumption of morphine equivalent post-operatively in adolescents aged 13 to 18 years who have…
- Trial name
- ViRAgeSS (NCT04892940)
- Testing
- Virtual Reality (VR) technique, Analgesic protocol
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Toulouse
Postoperative Pain, Acute
Postoperative Pain After Implementation of Standardized Pain Therapy Management in Orthopaedic Patients
The aim of this study is to examine the impact of implementing a standardized pain therapy protocol and their components on postoperative pain trajectories and postoperative outcomes such as increased opioid consumption and to…
- Trial name
- PAIN (NCT06363227)
- Testing
- Standardized pain management
- Volunteers
- 12,000 people
- Sponsor
- Schulthess Klinik
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Spine Injury, Trauma
Spine Trauma in the Elderly
Our study aims at investigating short and long-term outcomes following surgery for subaxial spine injuries in the elderly (octogenarian) population.
- Conditions
- Spine Injury, Trauma, Surgery
- Trial name
- NCT06019572
- Testing
- Spine decompression and fixation surgery
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Karolinska Institutet
Progressive Scoliosis
Surgical Treatment of Progressive Scoliosis With "NEMOST" Growing Rod
The purpose of this study is to evaluate the performance of the device "NEMOST" on maintaining of the correction of the scoliosis with growth preservation and avoiding iterative surgeries.
- Trial name
- NEMOST (NCT02266667)
- Testing
- 2 NEMOST rods : bilateral vertebral-pelvic implantation, 1 NEMOST rod :unilateral vertebral-pelvic implantation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adolescent Idiopathic Scoliosis, Multimodal Analgesia
Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
Patients with Adolescent Idiopathic Scoliosis may need surgery to correct their scoliosis. General anesthesia is required for this surgery, and a multimodal analgesic regimen using combinations of opioid and non-opioid…
- Conditions
- Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil
- Trial name
- NCT06096181
- Testing
- Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Scoliosis
Tranexamic Acid (TXA) Versus Epsilon Aminocaproic Acid (EACA) Versus Placebo for Spine Surgery
Tranexamic acid (TXA) and epsilon aminocaproic acid (EACA) have been reported to reduce blood loss in the cardiac surgery literature but they have not been reported in use head-to-head in the orthopedic surgery literature.
- Trial name
- NCT00958581
- Testing
- Tranexamic Acid, Normal Saline, Epsilon aminocaproic acid
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- NYU Langone Health
Lumbar Spine Degeneration, Arthrosis; Spine
Postoperative Bracing Patterns After Lumbar Surgery
A variety of postoperative bracing are routinely applied after spinal procedures but there are limited data regarding their efficacy, especially with the increasing use of internal fixation.Currently, no data are available…
- Conditions
- Lumbar Spine Degeneration, Arthrosis; Spine, Surgery
- Trial name
- NCT03427281
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Scoliosis Idiopathic, Scoliosis; Adolescence
Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery
Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for pediatric, idiopathic scoliosis surgery.
- Trial name
- NCT06086431
- Testing
- 0.9% sodium chloride, Dexamethasone, Dexmedetomidine
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Early-Onset Scoliosis Deformity of Spine
Long-Term Follow-Up Of Surgical Management Of Early Onset Scoliosis Using Growing Rods
The aim of this work is to evaluate the long-term outcome of the graduates (those who completed the gradual lengthening procedures), to better understand the full scope and natural course of Growing Rods treatment for EOS and to…
- Trial name
- NCT04945343
- Testing
- Growing Rods
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Spine Deformities, Idiopathic Scoliosis
Blood Propofol Concentrations in Children During Spinal Surgery
During major spinal surgery evoked potential monitoring is performed to detect spinal cord damage. Intra-venous anaesthesia is the preferred anaesthetic technique because volatile anaesthetic agents supress the evoked potentials.
- Conditions
- Spine Deformities, Idiopathic Scoliosis, Neuromuscular Dystrophy
- Trial name
- NCT01932424
- Testing
- Pelorus 1500, Propofol 2% (Diprivan 2%, Astra Zeneca UK)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Thoracolumbar Spine, Cervical Spine Injury
Clinical and Radiographic Outcomes of Spine Surgeries Utilizing Capri Cervical and Thoracolumbar Corpectomy Cage Systems
This is a retrospective and prospective observational, multi center study of subjects who have undergone or will undergo vertebral body replacement surgery in the cervical or thoracolumbar spine utilizing Stryker Capri Corpectomy…
- Trial name
- NCT05456633
- Testing
- Capri Cervical Static, CAPRI Static Expandable, Capri Thoracolumbar
- Sponsor
- K2M, Inc.
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median
Scoliosis; Spinal Fusion; Blood Transfusion; Operative Blood Loss
Blood Transfusion Risk Factors and Cell Saver Impact in Pediatric Scoliosis Surgery
Spine surgery for scoliosis correction in pediatric patients is a major procedure associated with a high risk of perioperative blood loss.
- Trial name
- NCT07661589
- Testing
- posterior Instrumented Spinal Fusion, Intraoperative Cell Saver Autologous Reinfusion
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- Mehdi Trifa
Ileus
Effect of Chewing Gum on Post-operative Ileus (GUMPI)
The purpose of this study is to determine whether chewing gum post-operatively decreases the time to first flatus or defecation in patients undergoing spine surgery as a indirect indicator of post-operative ileus.
- Trial name
- GUMPI (NCT02847364)
- Testing
- chewing gum
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Postoperative Nausea and Vomiting, Scoliosis
A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery
The aim of this clinical trial is to compare the effectiveness of two Serotonin (5- HT3) receptor antagonist, palonosetron and granisetron, administered along with dexamethasone as a preventive measure against early and delayed…
- Trial name
- PONV (NCT06540885)
- Testing
- Palonosetron (Group P), Granisetron (Group G)
- Where
- 2 sites in Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Scoliosis
Value of 3D Modeling in Spine Surgery
Adults (18 years and over) and children (10-17 years of age) scheduled for surgery to correct scoliosis will be included in this study, for which participation will last 6 months.
- Trial name
- NCT02771899
- Testing
- spineEOS software, EOS
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Columbia University