Clinical trials: Stable Angina Pectoris
Chronic Coronary Syndrome, Coronary Artery Disease
Feasibility of a Deep Learning-based Algorithm for Non-invasive Assessment of Vulnerable Coronary Plaque
The primary objective of this study is to assess the accuracy in terms of sensitivity, specificity, negative and positive predicted values of the DL-based algorithm with respect to correct identification of the plaque and…
- Conditions
- Chronic Coronary Syndrome, Coronary Artery Disease, Stable Angina, Acute Coronary Syndrome
- Trial name
- FOCUS DL (NCT06186336)
- Testing
- Deep Learning-based Vulnerable Plaque Detection and Assessment Tool
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- GE Healthcare
Slow Coronary Flow, Normal, or Near Normal Coronary Angiography
Effects of Nicorandil on Angina Symptoms in Patients With Coronary Slow Flow
Slow coronary flow is an angiographically diagnosed phenomenon defined as delayed opacification of epicardial arteries in the absence of significant arterial narrowing and blockade.
- Conditions
- Slow Coronary Flow, Normal, or Near Normal Coronary Angiography, Stable Angina
- Trial name
- NCT02254252
- Testing
- Nicorandil, Nitroglycerin
- Volunteers
- 54 people
- Sponsor
- Mashhad University of Medical Sciences
Coronary Heart Disease, Angina Pectoris
The Effects of Diesel Exhaust Inhalation On Exercise Capacity In Patients With Stable Angina Pectoris
The purpose of this study is to determine whether exposure to diesel exhaust (air pollution) has a functional impact on patients with stable angina pectoris.
- Trial name
- NCT00737958
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh
Chronic Coronary Syndrome, Stable Angina
Effectiveness and Tolerability of Trimetazidine 80mg Once Daily in Patients With Chronic Coronary Syndrome: The V-GOOD Study
The objective of this non-interventional multicentric study (NIS) is to investigate the efficacy and tolerability of treatment with Vastarel Caps LP® in symptomatic patients with angina over 3 months under conditions of daily…
- Trial name
- V-GOOD (NCT06464276)
- Testing
- No intervention
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- Ministry of Health, Brazil
Coronary Artery Disease
Ranolazine Loading to Prevent PCI-induced Myocardial Injury
It has previously been shown that pretreatment with ranolazine 1,000 mg twice daily for 7 days can significantly reduce procedural myocardial injury in elective percutaneous coronary intervention (PCI).
- Trial name
- TWILIGHT (NCT01491061)
- Testing
- Ranolazine
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Coronary Stenosis, Angina Pectoris
Evaluation of the Correlation Between the Coronary Stenosis Degree With FFRCT and the Grade of Stable Angina Pectoris
Angina pectoris is the most common clinical manifestation of coronary heart disease（CHD）, which is the main feature of chest pain caused by transient myocardial ischemia.
- Trial name
- NCT02802046
- Testing
- Computed tomographic angiography of coronary artery
- Volunteers
- 20 people
- Sponsor
- Guiyang No.4 People's Hospital
Non ST Elevation Acute Coronary Syndromes, Stable Coronary Syndromes
Appropriateness of Coronary Angioplasty in PAtients With isCHEmic Heart Disease
An observational, retrospective, multicenter, blinded adjudication study to evaluate the clinical appropriateness of Percutaneous Coronary Intervention (PCI) indication and execution in patients with stable Coronary Artery…
- Conditions
- Non ST Elevation Acute Coronary Syndromes, Stable Coronary Syndromes, NSTEMI, Unstable Angina
- Trial name
- APACHE (NCT02748603)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Italian Society of Invasive Cardiology
Chronic Stable Angina
Effects of Ranolazine and Exercise on Daily Physical Activity Trial
The primary objective is to assess whether the increased angina threshold on ranolazine and subsequent higher training intensity will result in improved exercise tolerance and oxygen consumption; and greater than that observed…
- Trial name
- EREDA (NCT01948310)
- Testing
- Ranolazine, Aerobic Exercise
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
Stable Angina
Atorvastatin and Clopidogrel HIgh DOse in Stable Patients With Residual High Platelet Activity
The purpose of this study is to evaluate if high-dose (80mg/day) atorvastatin might exert an adjunctive anti-platelet effect compared to high-dose clopidogrel (150mg/day) in stable patients with high on-treatment reactivity…
- Trial name
- ACHIDO (NCT01335048)
- Testing
- atorvastatin and clopidogrel, Clopidogrel
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ospedale Misericordia e Dolce
Coronary Artery Disease, Stable Angina
BMX Alpha Registry: a Post-market Registry of the BioMatrix Alpha TM
Prospective, multi-center, registry designed to enrol up to 2,000 patients in up to 35 International centers. All patients will receive a BioMatrix AlphaTM stent as per clinical practice and will be followed for 2 years for data…
- Conditions
- Coronary Artery Disease, Stable Angina, Ischemia, Acute Coronary Syndrome
- Trial name
- NCT02871622
- Testing
- BioMatrix AlphaTM
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Biosensors Europe SA
Contrast Induced Nephropathy
Assessment of the Effect of Atorvastatin on Prevention of CIN in Patients Undergoing Coronary Angiography
As the effect of statin use before the angiography to prevent contrast induced nephropathy (CIN) is not well-known, the aim of the current study is to assess the effect of atorvastatin on prevention of CIN in patients undergoing…
- Trial name
- CIN (NCT02113540)
- Testing
- Atorvastatin
- Where
- Iran
- Sponsor
- Isfahan University of Medical Sciences
Stable Angina, Unstable Angina, Silent Coronary Ischemia, Coronary Artery Disease
ISAR-DAPT (A Comparative Evaluation of Efficacy and Safety in the 3-Months DAPT Group vs. the 6-Months DAPT Group of Patients Treated With the Coroflex ISAR Stent; A Prospective, Multicenter, Randomized, Open-Label Clinical Trial)
This clinical trial studies patients treated with the Coroflex ISAR Stent for coronary artery disease in order for the objective of verifying the non-inferiority of results that among patients who were administered DAPT for 3…
- Trial name
- NCT02609698
- Testing
- Coroflex ISAR, 3 months DAPT, 6 months DAPT
- Where
- South Korea
- Volunteers
- 906 people
- Sponsor
- Ajou University School of Medicine
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Stable Angina (SA), NSTE-ACS (NSTEMI and UA)
Utilisation of Angiox® in European Practice
The objective of this study is to determine utilisation patterns in patients receiving Angiox® in participating European centres.
- Conditions
- Stable Angina (SA), NSTE-ACS (NSTEMI and UA), STEMI (STE-ACS)
- Trial name
- EURO-vision (NCT01011504)
- Where
- 2 sites in France, Germany
- Volunteers
- 2,019 people
- Sponsor
- The Medicines Company
Acute Myocardial Infarction, Stable Angina
Development and Efficacy Evaluation of Integrated Chronic Care and Health Promotion Model for Patients With Coronary Artery Disease in Taiwan
The hypothesis of this project is to examine whether the integrated health care program as the intervention group can reduce the recurrence and mortality of coronary artery-related diseases than the traditional one as the…
- Trial name
- NCT01357096
- Testing
- Integrated health care team, Traditional group
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Stable Angina, Unstable Angina
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
We had little experience in coronary intervention with recently introduced newer drug-eluting stent (DES) platforms, despite great anticipation, and optimal duration of dual antiplatelet therapy (DAPT) for these stent systems…
- Conditions
- Stable Angina, Unstable Angina, Non-ST Segment Elevation Myocardial Infarction
- Trial name
- HOST-IDEA (NCT02601157)
- Testing
- 3-months DAPT, 1-year DAPT
- Where
- 12 sites in South Korea
- Volunteers
- 2,173 people
- Sponsor
- Seoul National University Hospital
Chronic Stable Angina
A Clinical Trial of a Self-Management Education Program for People With Chronic Stable Angina
The purpose of this clinical trial was to determine the effectiveness of a supportive and educational self-management program for improving health-related quality of life (HRQOL), angina symptoms, and self-efficacy and…
- Trial name
- NCT00350922
- Testing
- Psychoeducation
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- University of Toronto
Acute Coronary Syndrome, STEMI - ST-segment Elevation Myocardial Infarction
Kitasato PCI Registry
The Kitasato PCI Registry is a single-center, observational, prospective study. This study aims to investigate the impact of characteristics in clinical manifestation, patients' background, procedure of percutaneous coronary…
- Conditions
- Acute Coronary Syndrome, STEMI - ST-segment Elevation Myocardial Infarction, NSTEMI - Non-ST-Segment Elevation Myocardial Infarction, Atherosclerosis
- Trial name
- NCT05308329
- Testing
- Intra-coronary imaging device, PCI procedural characteristics
- Where
- Japan
- Volunteers
- 4,500 people
- Sponsor
- Kitasato University
Angina Pectoris, Coronary Heart Disease
Effects of Ambient Air Pollution Exposure in Patients With Stable Angina Pectoris During Normal Daily Activities
The purpose of this study is to identify whether exposure to ambient levels of air pollution during normal daily activities has a functional impact on patients with coronary heart disease
- Trial name
- NCT00738491
- Where
- 2 sites in United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Edinburgh
Stable Angina, Unstable Angina
International Collaboration of Comprehensive Physiologic Assessment
The current study evaluated prognostic implication of comprehensive physiologic assessment using fractional flow reserve, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR).
- Conditions
- Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT03690713
- Testing
- Fractional flow reserve, coronary flow reserve, and index of microcirculatory resistance
- Where
- 4 sites in Japan, South Korea and 1 more
- Volunteers
- 1,397 people
- Sponsor
- Seoul National University Hospital