Clinical trials: Staining
Wilms Tumor, Relapse
The Use of Immunohistochemical Staining for the Prediction of Wilms Tumour Progression and Recurrence
Wilms' tumour staging and grading are used to give an idea about the prognosis. Advanced staging, diffuse anaplasia, predominant blastemal elements and lymph node invasion are indicators of poor prognosis.
- Conditions
- Wilms Tumor, Relapse, Death
- Trial name
- NCT04758455
- Testing
- P53, Ki67 and Cyclin A IHC.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Staining Effect of Chlorhexidine
Spectrophotometric Evaluation of Chlorhexidine Pigmentations After Oral Surgery: a Prospective Randomized Clinical Trial
The aim of this clinical trial was to evaluate through a clinical spectrophotometric analysis the staining side effect of a 0.2% CHX mouthwash containing an anti discoloration system (ADS) compared with a 0.12% and a 0.2% CHX…
- Trial name
- NCT02132546
- Testing
- Chlorhexidine
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- dott. Lorenzo Bevilacqua
Bone Diseases
Use of a Radiopaque Localizer Grid and Methylene Blue Staining as an Aid to Reduce Radiation Exposure
Localization of small femur lesions for resection can be challenging and may be associated with the need for significant fluoroscopic imaging and tissue dissection.
- Trial name
- NCT02969005
- Testing
- surgical treatment
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Port-wine Stain
Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment
Port-wine stain is a congenital, progressive vascular malformation of human skin involving post-capillary venules that occurs in an estimated 0.3% of children and can alter personality development and psychological in children.
- Trial name
- NCT01774552
- Testing
- Photo Acoustic Microscopy and Optical Coherence tomography
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Black Stains
A Crossover Clinical Study to Evaluate the Effect of Chitosan Mouthwash on Recurrence of Black Stains in Pediatric Patients
The goal of this clinical trial is to learn if Chitosan mouthwash works to affect the recurrence of black stains in pediatric patients.
- Trial name
- NCT06714695
- Testing
- Chitosan
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Aligner Staining
Cleaning Agents Impact on Invisalign Aligners: A Cross-Over Randomized Trial
Today, the increasing aesthetic expectations of the patients, showing its effect in the field of orthodontics, leads to the orientation towards aesthetic materials.
- Trial name
- İnvisalign (NCT05213650)
- Testing
- non-abrasive toothpaste, abrasive toothpaste, Efferdent
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Port Wine Stains
Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains
The goal of this clinical trial is to learn if the use of rapamycin cream can be used as a treatment together with pulsed dyed laser in treating port wine stain birthmarks.
- Trial name
- NCT07436611
- Testing
- Rapamycin cream, Pulsed dyed laser
- Where
- 2 sites in United States, Spain
- Volunteers
- 30 people
- Sponsor
- AFT Pharmaceuticals, Ltd.
Port Wine Stain
Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences
The purpose of the study is to improve the efficacy of pulsed dye laser treatment of port wine stain birthmarks. Involvement in the protocol will involve formal documentation of the level of treatment pain, duration of…
- Trial name
- NCT00540371
- Testing
- Port wine stain Birthmark
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Undiagnosed IgG4 Related Diseases
Retrospective Study for Diagnosis of Undetected IgG4 Related Diseases in Patients With High Serum IgG4 Levels.
Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognized syndrome of unknown etiology comprised of a collection of disorders that share specific pathologic, serologic, and clinical features.
- Trial name
- NCT02229448
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Meir Medical Center
Comparative Study, Aesthetic Perception
Parental Perceptions and Acceptance of Silver Diamine Fluoride in Spain and Italy
Assessing parental aesthetic acceptability of Silver Diamine Fluoride (SDF) staining is crucial for its potential implementation in paediatric dentistry.
- Conditions
- Comparative Study, Aesthetic Perception, Acceptability, SDF
- Trial name
- SDF (NCT06384326)
- Where
- Italy
- Volunteers
- 501 people
- Sponsor
- University of Bologna
Myopia, Hyperopia
Corneal and Conjunctival Sensitivity and Staining Study
The primary objective of this study is to compare subjective symptoms and ocular health in a group of individuals who are currently wearing soft contact lenses on a daily wear basis, after a short period of no lens wear and…
- Trial name
- NCT00455455
- Testing
- Optifree RepleniSH Multipurpose Disinfecting Solution, ReNu Multiplus Multipurpose Solution
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Melanoma
Treatment of Port Wine Stains in Children With Pulsed Dye Laser and Timolol Gel
Pulsed dye laser (PDL)is the gold standard treatment of port wine stains (PWS). However, many sessions are required and failure or relapses are not uncommon.
- Trial name
- NCT01272609
- Testing
- Timolol + LCP, LCP
- Where
- 10 sites in France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Teeth Staining
Clinical Efficacy of Antivet Versus Phosphoric Acid and Hydrochloric Acid in Microabrasion
This clinical trial will be conducted to assess the clinical efficacy of using Antivet cleaning enamel solution or hydrochloric acid and phosphoric acid in microabrasion technique for mild to moderate intrinsic stained teeth.
- Trial name
- NCT07709286
- Testing
- (Antivet, MDC DENTAL, Zapopan Jalisco México), Opalustre, phosphoric acid 37% and aluminium oxid 50 microns
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr University for Science and Technology
Discoloration, Tooth
Effect of Glutathione vs KI in Reducing SDF Staining When Used in Treatment of Primary Carious Teeth
Although black staining is considered a drawback that is clinically observed following SDF application and is the main primary barrier for its use clinically .
- Trial name
- NCT04816487
- Testing
- Potassium Iodide or Glutathione
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Port-Wine Stain
Measurement Skin Temperature During Pulsed Laser Exposure
Lasers are the treatment modality of choice for Port Wine Stain birthmarks.The epidermis is not totally spared due to partial absorption of energy therein by melanin that presents an optical barrier through which the light must…
- Trial name
- NCT00540917
- Testing
- cooling spray during laser treatment
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Port-wine Stain
A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain
This pilot study aims to evaluate the efficacy and safety of hemoporfin photodynamic therapy (PDT) with different light doses for port-wine stain (PWS） in 7-14 years old children.
- Trial name
- NCT03125057
- Testing
- Hemoporfin PDT
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Vascular Diseases, Vascular Malformation
A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular Pathology
Laser treatment (LT) is the first-line treatment for Vascular Pathology. However even when LT is based on the selective photothermolysis it causes the first-degree burns.
- Conditions
- Vascular Diseases, Vascular Malformation, Capillary Malformation-Arteriovenous Malformation, Port-Wine Stain
- Trial name
- DOUBLE-SKIN (NCT04999618)
- Testing
- Haemoblock
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Center for Vascular Pathology, Moscow
Port-wine Stains (PWS), Vascular Birthmark
AdvaTx Laser Treatment for Vascular Birthmarks
The primary objective of the present study is to get experiences with the use of CE-marked ADVATx laser treatment for port-wine stains.
- Trial name
- ADVA-PWS (NCT07250945)
- Testing
- ADVATx laser treatment
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- Szeged University
Port Wine Stain
The Role of Angiogenesis-related Pathways in the Development of Port Wine Stains
1. Port wine stain (PWS) is a congenital, progressive vascular malformation of human skin involving the superficial vascular plexus that occurs in estimated 3-5 children per 1,000 live births.
- Trial name
- NCT03948997
- Testing
- Pulsed dye laser (PDL)
- Volunteers
- 80 people
- Sponsor
- xjpfW
Black Stain Dental, Dental Black Stain, Black Stain*, Black Stains, Tooth Stains
Assessment of Salivary Bacterial Level and Dental Caries Experience in a Group of Egyptian Children With Black Stained Teeth
Black stains (BS) are type of extrinsic discoloration of the tooth. It's characterized as dark lines or an incomplete coalescence of dark dots found mostly on cervical third of the crown.
- Trial name
- NCT03563469
- Testing
- Salivary bacterial and pH level
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cairo University