Clinical trials: Step
IVF
Direct Thawing of Vitrified Human Blastocyst
There are more than million frozen embryo transfers around the world each year; a faster, safer, and cheaper method can save a significant amount of money for patients undergoing IVF treatment worldwide.
- Trial name
- NCT06322823
- Testing
- direct thawing, Vitrification
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Autism Spectrum Disorder
STEPS: Stepped Transition in Education Program for Students With ASD
Young adults who have Autism Spectrum Disorder (ASD) without co-occurring intellectual impairment face a fairly unique set of challenges as they transition out of secondary school.
- Trial name
- STEPS (NCT02468505)
- Testing
- STEPS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Virginia Polytechnic Institute and State University
Strep Throat
Evaluation of the IND One Step Strep A Rapid Test vs. Culture
The purpose of this study is to demonstrate the ability of the IND One Step Strep A test to accurately test a throat swab specimen from a symptomatic patient for the presence or absence of Group A Streptococcus (Strep A) when…
- Trial name
- NCT01491776
- Where
- 3 sites in United States
- Volunteers
- 315 people
- Sponsor
- IND Diagnostic Inc.
Marfan Syndrome
Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and Beyond
Marfan patients are at risk of sudden death due to weakening of the wall of the large blood vessel leading from the heart (aorta).
- Trial name
- NCT03567460
- Testing
- Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
STEPS Implementation Trial
This study will inform understanding of how to support emerging adults with autism spectrum disorder (ASD). The investigators will use a theoretically informed and research-based transition support program developed for people…
- Trial name
- NCT05695885
- Testing
- STEPS, Services as usual (SAU)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Dental Pulp Necrosis, Dental Pulp Disease
Digitized Assessment for the Survival of Mature Anterior Teeth With Periapical Lesion After One Step Regenerative Approach Using Different Asepsis Maneuvers
Trial is designed to allow revascularization and tissue engineering in necrotic teeth with peripical lesion in a single visit approach.
- Conditions
- Dental Pulp Necrosis, Dental Pulp Disease, Dental Pulp; Degeneration
- Trial name
- RCT (NCT03652129)
- Testing
- Disinfection
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ankle Injuries
Kinesiology Taping and Ankle Stability in Acute Injuries During Stair Descent
Background: Acute ankle injuries are common in sports and daily activities. Kinesiology taping enhances lower limb motion patterns, joint stability, and balance during descending stair activity in such patients.
- Trial name
- KTAS-SD (NCT06936033)
- Testing
- Kinesiology taping
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Ningbo University
Embryo Development
Culture Media and Blastocyst Development
The aim of this non-interventional study is to compare the blastulation rate per fertilized oocyte in two different single step culture media commercially available (GEMS and Irvine culture media).
- Trial name
- NCT03497052
- Testing
- In vitro culture in medium 1, In vitro culture in medium 2
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Clinica Valle Giulia
Acute Pancreatitis
Timing of Surgical Intervention After Percutaneous Catheter Drainage in STEP UP Approach for Severe Acute Pancreatitis
1. To determine the appropriate timing of surgical intervention after Percutaneous Catheter Drainage (PCD) in infected pancreatic necrosis (IPN). 2.
- Trial name
- NCT01527084
- Testing
- surgical intervention after percutaneous catheter drainage
- Where
- 2 sites in India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Schizophrenia and Disorders With Psychotic Features
Specialized Treatment Early in Psychosis (STEP)
The purpose of this study is to understand the effectiveness of a specialized package of phase-specific treatments for individuals in the midst of their first episode of psychosis.
- Trial name
- STEP (NCT00309452)
- Testing
- Cognitive Behavioral Group Therapy, Cognitive remediation, Medications
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Yale University
HIV Infections
Evaluation of HIV-1 Recent Infection Testing in Rwanda
The study is a longitudinal, observational cohort study of people who are newly-diagnosed with HIV who consent to recency testing and participate in index testing services, and their disclosed contacts.
- Trial name
- NCT05063487
- Testing
- Return of recent classification, Return of long-term classification
- Where
- Rwanda
- Volunteers
- 1,588 people
- Sponsor
- Columbia University
Autism, Autism Spectrum Disorder
Intensive Intervention for Toddlers With Autism (EARLY STEPS)
Goals of the current project: (1) Does the Early Start Denver Model experimental intervention for toddlers with autism reduce disability associated with autism significantly more than standard community interventions?; and (2)…
- Trial name
- NCT00698997
- Testing
- Early Start Denver Model, Standard community care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of California, Davis
Thoracic Injury
Delphi Study to Identify Crucial Steps and Errors in the Placement of Chest Tubes
The goal of this Delphi study is to identify the crucial steps and the errors in Chest Tube Insertion (CTI). These steps and errors will be used for the development of a new assessment tool based on international consensus.
- Trial name
- NCT05623631
- Testing
- Survey
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Placenta Accreta Spectrum
Comparison Between 3 Conservative Surgeries for Placenta Accreta Spectrum
Comparison between modified one-step surgery vs. Segment Resection vs. placental bed suturing for management of placenta accreta spectrum
- Trial name
- NCT07520201
- Testing
- Modified one-step surgery, Segment Resection, Placental bed suturing
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Squamous Cell Carcinoma of the Oropharynx
Evaluation of Tongue Base MucOsectomy & Step sErial Sectioning
Squamous cell carcinoma (SCC) is a cancer that originates from the cells lining the body and can spread into the lymph glands and beyond. Some patients first present with an SCC which has moved to the lymph glands of the neck.
- Trial name
- MOSES (NCT04151134)
- Testing
- Step serial sectioning histological processing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Parkinson Disease, Fall
Steps Against the Burden of Parkinson's Disease - RCT Kiel
Parkinson's disease (PD) affects over 10 million worldwide, causing unstable gait and falls in 70% of patients despite medication. This leads to confidence loss, isolation, fractures, and hospitalizations.
- Trial name
- StepuP (NCT07058285)
- Testing
- Speed-dependent treadmill training (SDTT), SDTT+ anteroposterior perturbations
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Kiel
Cerebral Palsy
Sensory-Motor Integration Versus Virtual Reality-Based Exercise in Children With Cerebral Palsy
This study aims to compare the clinical effects of a sensory-motor integration-based exercise program and a virtual reality-based exercise program on gross motor function, balance, and functional mobility in children with…
- Trial name
- NCT07836517
- Testing
- Sensory-Motor Integration-Based Exercise Program, Virtual Reality-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Yeditepe University
Peanut Allergy, Food Allergy
STEP-IT-UP - Peanut Allergy Study for Infants
Multicenter randomized (1:1) trial of strict avoidance versus sub-threshold dietary introduction of peanut in peanut allergic infants 4-14 months of age who react at a minimum cumulative dose of at least 430 mg of peanut protein…
- Trial name
- NCT04761835
- Testing
- Peanut powder or peanut butter
- Sponsor
- Johns Hopkins University
Hyperglycemia
The Effect of American Ginseng Root and Its Components on Glycemia in Healthy Individuals
To determine the effect of polysaccharides from American ginseng root on postprandial glycemia in healthy individuals.
- Trial name
- NCT00367926
- Testing
- American ginseng root / polysaccharides
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Risk Factor Modification Centre
Anterior Cruciate Ligament Injuries
Steps Towards Osteoarthritis Prevention
Optimal knee joint loading, which refers to the forces acting on the knee caused by daily activities such as daily steps, plays an essential role in maintaining knee articular cartilage health and reducing the risk of…
- Trial name
- STOP (NCT06193343)
- Testing
- Adaptive Daily Step Promotion
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Georgia