Clinical trials: Step
Depressive Symptoms, Happiness
Believing People Can Change: A Randomized Controlled Trial of an Incremental Theory Intervention in Adolescence
This study will test the effectiveness of a brief educational intervention that teaches youth that they can grow and change, known as "growth mindset." Similar growth mindset interventions have improved youths' well-being and…
- Conditions
- Depressive Symptoms, Happiness, Life Satisfaction
- Trial name
- NCT04133389
- Testing
- Growth mindset of personality educational intervention, Growth mindset of athletic ability educational intervention
- Where
- Canada
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Psychotic Disorders, Personality Disorders
The Staged Treatment in Early Psychosis Study
A sequential multistage randomised clinical trial (SMART) to produce evidence to guide a step-wise clinical approach for the treatment of ultra high risk patients and reduction of risk for psychosis and other deleterious clinical…
- Conditions
- Psychotic Disorders, Personality Disorders, Clinical High Risk
- Trial name
- STEP (NCT02751632)
- Testing
- Support and Problem Solving Therapy, Cognitive Behavioural Case Management, Fluoxetine
- Where
- 5 sites in Australia
- Volunteers
- 342 people
- Sponsor
- Orygen
Asthma
Study of Safety of QAW039 in Patients With Asthma Inadequately Controlled on Standard-of-care Asthma Treatment
This study was a 2-treatment period, randomized, multicenter parallel-group study. The overall purpose of this study was to provide long- term safety data for fevipiprant (QAW039) (Dose 1 and Dose 2), compared with placebo, when…
- Trial name
- NCT03052517
- Testing
- QAW039 150 mg, QAW039 450 mg
- Where
- 347 sites in United States, Argentina and 40 more
- Volunteers
- 2,538 people
- Sponsor
- Novartis Pharmaceuticals
Autism, Autism Spectrum Disorder
Intensive Intervention for Toddlers With Autism (EARLY STEPS)
Goals of the current project: (1) Does the Early Start Denver Model experimental intervention for toddlers with autism reduce disability associated with autism significantly more than standard community interventions?; and (2)…
- Trial name
- NCT00698997
- Testing
- Early Start Denver Model, Standard community care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of California, Davis
Anterior Cruciate Ligament Injuries
Steps Towards Osteoarthritis Prevention
Optimal knee joint loading, which refers to the forces acting on the knee caused by daily activities such as daily steps, plays an essential role in maintaining knee articular cartilage health and reducing the risk of…
- Trial name
- STOP (NCT06193343)
- Testing
- Adaptive Daily Step Promotion
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Georgia
Medication Nonadherence, Depression
The Effectiveness of CBI on Depression and Adherence in HIV Infected Adolescents
Aim: To explore the effectiveness of psychoeducation and problem-solving (Life-steps) on depression and adherence in HIV-infected adolescents.
- Conditions
- Medication Nonadherence, Depression, HIV Infections
- Trial name
- NCT05482217
- Testing
- Psychoeducation, problem solving and rehearsal (cognitive behavioural intervention)
- Where
- Botswana
- Volunteers
- 25 people
- Sponsor
- University of Botswana
4-STEP-Training Program for Social Media Addiction
The Effectiveness of 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) and Psychological Problems Among Adolescence
This study evaluates the effectiveness of the 4-STEP Training Program in reducing social media addiction and improving psychological well-being among adolescents.
- Trial name
- 4-STEP-TPS (NCT07564115)
- Testing
- 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Placenta Accreta
Bilateral Uterine Artery Ligation in PPC Technique for Management of PAS
Aim of the study Primary outcomes: 1. The effect of bilateral uterine artery ligation in reducing intraoperative bleeding in women underwent PPC as a conservative surgical technique. 2. Decrease surgical time.
- Trial name
- NCT05314595
- Testing
- bilateral uterine artery ligation
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Literacy, Parent-Child Relations
Testing an App-Based Approach to Reading and Screen Time Guidance for Parents of Infants
The American Academy of Pediatrics (AAP) recommends that parents read to their children as often as possible beginning in infancy and limits on screen time at all ages, yet many families question the value of reading to infants…
- Conditions
- Literacy, Parent-Child Relations, Language Development
- Trial name
- NCT05508282
- Testing
- Reading Bees app and children's book to enhance parent-infant reading quality (0-2 month visit), Reading Bees app and children's book to encourage alternatives to digital media (6-month visit)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Thoracic Injury
Delphi Study to Identify Crucial Steps and Errors in the Placement of Chest Tubes
The goal of this Delphi study is to identify the crucial steps and the errors in Chest Tube Insertion (CTI). These steps and errors will be used for the development of a new assessment tool based on international consensus.
- Trial name
- NCT05623631
- Testing
- Survey
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Dental Pulp Necrosis, Dental Pulp Disease
Digitized Assessment for the Survival of Mature Anterior Teeth With Periapical Lesion After One Step Regenerative Approach Using Different Asepsis Maneuvers
Trial is designed to allow revascularization and tissue engineering in necrotic teeth with peripical lesion in a single visit approach.
- Conditions
- Dental Pulp Necrosis, Dental Pulp Disease, Dental Pulp; Degeneration
- Trial name
- RCT (NCT03652129)
- Testing
- Disinfection
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Medical Emergencies
FUSE - Feasibility of Patient Held Sensors for Medical Emergencies
The investigators want to study how wearable devices can help track health changes in people when they are not feeling well. Normally, clinicians compare someone's vital signs, like heart rate, to average ranges from healthy…
- Trial name
- FUSE (NCT06199310)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Betsi Cadwaladr University Health Board
IVF
Direct Thawing of Vitrified Human Blastocyst
There are more than million frozen embryo transfers around the world each year; a faster, safer, and cheaper method can save a significant amount of money for patients undergoing IVF treatment worldwide.
- Trial name
- NCT06322823
- Testing
- direct thawing, Vitrification
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Severe Asthma
Phase 3b Study in Patients With Severe Asthma Treated With Tezepelumab
This study aims to explore the potential for Tezepelumab-treated severe asthmatic patients to effectively and safely reduce their background maintenance medication while maintaining asthma symptom control.
- Trial name
- TAPER (NCT07363642)
- Testing
- Tezepelumab
- Where
- 75 sites in China
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Step Time and Length, Symmetry
The Contribution of Heels for Walking Quality Among Children With Muscular Dystrophy
During the stand phase the DMD foot is too plantarflexed in addition patients adopt a higher flexion and abduction of the hip in order to advance the swinging limb.
- Conditions
- Step Time and Length, Symmetry, Step Time and Length Variability, Heart Rate
- Trial name
- NCT01638169
- Testing
- adding a heel
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Anxiety, Depression
The Clinic Treatment Project
The Clinic Treatment Project tested two alternative methods of delivering evidence-based practices within public community-based mental health clinics, using training and supervision procedures designed for the settings and users.
- Conditions
- Anxiety, Depression, Problem Behavior
- Trial name
- CTP (NCT01178554)
- Testing
- psychotherapy, evidence-based treatment, modular evidence-based treatment
- Where
- 2 sites in United States
- Volunteers
- 203 people
- Sponsor
- Judge Baker Children's Center
Leukemia, Acute Leukemia
Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children and, along with lymphoblastic lymphoma, represents the most common group of childhood lymphoid malignancies.
- Conditions
- Leukemia, Acute Leukemia, Acute Lymphoid Leukemia, Lymphoblastic Lymphoma
- Trial name
- STEP-ALL (NCT07634653)
- Testing
- Exercises
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
HIV-1-infection, Sexually Transmitted Diseases
Thetha Nami Ngithethe Nawe ("Let's Talk"): Step Wedge cRCT of Peer Led Community PrEP and SRH for Youth in South Africa
Study Hypothesis: Social mobilisation will attract and engage young people into decentralised sexual reproductive health (SRH) services where HIV prevention is tailored to need.
- Trial name
- NCT05405582
- Testing
- Community-based differentiated HIV prevention incl.PrEP with SRH, Primary Health Clinic based HIV prevention and care
- Where
- South Africa
- Volunteers
- 8,716 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
Biliary Tract Neoplasm, Cholangiocarcinoma
MRCP Diagnoses EHCC Better When Combined DWI
Researching the diagnostic significance of Biliary Tract Neoplasm under combining DWI sequence with MRCP versus MRCP only separately.
- Trial name
- NCT01595217
- Testing
- 3T MRI
- Where
- China
- Volunteers
- 99 people
- Sponsor
- China Medical University, China
Strep Throat
Evaluation of the IND One Step Strep A Rapid Test vs. Culture
The purpose of this study is to demonstrate the ability of the IND One Step Strep A test to accurately test a throat swab specimen from a symptomatic patient for the presence or absence of Group A Streptococcus (Strep A) when…
- Trial name
- NCT01491776
- Where
- 3 sites in United States
- Volunteers
- 315 people
- Sponsor
- IND Diagnostic Inc.