Clinical trials: Sterility, Female
Infertility, Female
Sildenafil and Outcome of IVF/ICSI Cycles
Adequate growth of the endometrium is crucial for implantation. Accordingly, the pregnancy success rate of patients with a thin endometrium is low.
- Trial name
- NCT03192709
- Testing
- Sildenafil vaginal suppositories
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Infertility Unexplained, Fertility Disorders
Hypnofertility for Women Undergoing In Vitro Fertilization (HWUIVF)
This randomized controlled study aimed to specify whether the interventions based on Hypnofertility would lead to increased fertility preparedness and pregnancy outcomes, decreased cortisol levels of women undergoing In Vitro…
- Trial name
- NCT04141436
- Testing
- Interventions Based on Hypnofertility, Routine clinical procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Genetic Disorder, Infertility
Inherited Reproductive Disorders
Background: During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. Some people have low hormone levels that severely delay or prevent puberty.
- Conditions
- Genetic Disorder, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01500447
- Where
- 2 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Facilitated Tucking, Non Nutritive Sucking
Efficacy of Facilitated Tucking During Pain Procedure in Preterm Infants
Preterm infants undergo very frequent painful procedures during neonatal care particularly during the first few days. The support for the pain of the preterm is a priority for nurses and neonatologists.
- Conditions
- Facilitated Tucking, Non Nutritive Sucking, Preterm, Pain Relief
- Trial name
- BABYDOUL (NCT02096822)
- Testing
- Facilitated tucking + non-nutritive sucking, non-nutritive sucking
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility, Infertility, Female
Developmental Epidemiological Study of Children Born Through Reproductive Technology
DESCRT will be a long-term study that both looks back in time, at successful pregnancies, and forward in time at early pregnancy and long-term as these children grow.
- Conditions
- Infertility, Infertility, Female, Infertility, Male, Infertility Primary
- Trial name
- DESCRT (NCT03799107)
- Where
- United States
- Volunteers
- 2,020 people
- Sponsor
- University of California, San Francisco
Infertility, Female
CAPA In-vitro Oocyte Maturation
In vitro oocyte maturation (IVM) is a mild-approach assisted reproductive technology (ART). Because of its simplicity, the more favorable financial implications (reduced cost) for patients, and the lower health risk profile of…
- Trial name
- NCT06984081
- Testing
- CAPA IVM
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Infertility, Female
Ovarian Tissue Cryopreservation
Ovarian Tissue Freezing For Fertility Preservation In Girls Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen
- Trial name
- OTC (NCT06710769)
- Testing
- Ovarian tissue removal will be performed laparoscopically
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Phoenix Children's Hospital
Polycystic Ovary Syndrome, IVF
Follicular Fluid Raman Shifts and IVF Outcomes
This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical…
- Trial name
- NCT04838535
- Testing
- Raman spectrum
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Acute Ovarian Failure, Infertility
Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy
Background: Medical advances have improved survival rates for many cancers and other illnesses. This means that more people are coping with the long-term effects of these treatments. Some treatments can cause female infertility.
- Conditions
- Acute Ovarian Failure, Infertility, Early Menopause And Infertility In Females After Treatment For Childhood Cancer
- Trial name
- NCT05440617
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility, Infertility, Female
Retrospective Study on the Use, Efficiency, and Safety of the At-home Mosie Kit
This study examines the experience of people who have selected to use the at-home insemination Mosie Kit to understand the user's experience, the perceived safety and the efficiency.
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- NCT04646291
- Testing
- Insemination with the Mosie Baby Kit
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Mosie Baby
Fluid Loss, Dehydration
The Application of Sterile Water to the Skin of Extremely Low Birth Weight (ELBW) Infants
Extremely low birth weight infants have significant water loss through their skin immediately after birth. This significant fluid loss is because they have large amounts of fluids, have immature skin and large surface area.
- Conditions
- Fluid Loss, Dehydration, Extreme Immaturity
- Trial name
- NCT02052284
- Testing
- Sterile water application
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- George Washington University
Infertility, Female
Heated and Non Heated Ovarian Aspiration Needle Protocol
The success of IVF is influenced by factors as cause of infertility and age. Furthermore, there is a large influence of external factors, from the laboratory environment, handling and cultivation of gametes and embryos.
- Trial name
- NCT05683639
- Testing
- warming of the follicular aspiration needle
- Where
- Brazil
- Volunteers
- 179 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Infertility, Female, Thrombophilia
Effect of Prophylatic Use of Enoxaparin in Women Undergoing in Vitro Fertilization Treatment
Retrospective study designed to evaluate outcomes in patients undergoing assisted reproduction. Some of them had thrombophilia, and part of them was treated with enoxaparin, started on the day of embryo transfer, and the other…
- Conditions
- Infertility, Female, Thrombophilia, Fertilization in Vitro
- Trial name
- NCT05225155
- Testing
- Enoxaparin
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Faculdade de Medicina do ABC
Infertility, Female
A Post Marketing Observational Study of the Safety and Efficacy of Elonva (Corifollitropin Alfa) in General Practice (P08165)
This observational study will examine the safety and efficacy profile of Elonva (corifollitropin alfa) when administered in Korean women undergoing controlled ovarian stimulation (COS) in combination with a gonadotropin-releasing…
- Trial name
- NCT01408615
- Testing
- corifollitropin alfa
- Volunteers
- 472 people
- Sponsor
- Organon and Co
Infertility, Female, Miscarriage
Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?
This study aims to explore the potential correlation between decreased ovarian reserve and previous history of early miscarriage.
- Conditions
- Infertility, Female, Miscarriage, Miscarriage, Recurrent, IVF
- Trial name
- NCT05969574
- Testing
- Transvaginal ultrasound, Blood test AMH
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 2,059 people
- Sponsor
- ART Fertility Clinics LLC
Endometriosis, Infertility
Harnessing the Disease Signatures From Endometrium and Menstrual Blood to Identify Avenues for the Treatment of Chronic Conditions Such as Endometriosis and Related Pathologies: This is an Observational Study Aimed at Shedding Light on Women's Health
Many women's health conditions have limited treatments available and poor outcomes, in part due to the lack of understanding of disease processes and lack of data available.
- Conditions
- Endometriosis, Infertility, Endometrial Cancer, Adenomyosis, Endometriosis
- Trial name
- CYCLE_ENDO (NCT06990971)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cycle Therapeutics Ltd
Ovarian Diseases, Fertility Issues
A Novel Ovarian Reserve Monitoring Algorithm for Patients at Risk of Ovarian Injury From Gonadotoxic Therapy
This is an observational cohort study to examine the use of a novel proposed ovarian reserve monitoring algorithm to (1) identify patients who are at risk of DOR and POI from gonadotoxic therapy, (2) minimize time from treatment…
- Conditions
- Ovarian Diseases, Fertility Issues, Gonadal Disorders
- Trial name
- MA (NCT05048654)
- Sponsor
- University of Colorado, Denver
Infertility and at High Risk of OHSS
Dual Trigger to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022228
- Testing
- triptorelin, hCG
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chenshiling
Female Infertility
Follow-up of Ovarian Function in Young Women Who Underwent Ovarian Cortex Cryopreservation
Evaluation of ovarian function by a questionnaire and by medical file analysis of women and girls who underwent ovarian cortex cryopreservation for fertility preservation between 1997 an 2013 in the investigators' institution in…
- Trial name
- NCT02454829
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 546 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain