Clinical trials: Steroidogenesis
Friedreich's Ataxia, Steroidogenesis
FRIEDREICH ATAXIA- STEROIDOGENESIS
Friedreich's ataxia (FA) is a rare autosomal recessive disorder caused by GAA repeat expansion in the FXN gene, leading to impaired iron-sulfur (Fe-S) cluster biosynthesis and mitochondrial dysfunction.
- Trial name
- FRIEDSTERO (NCT07123142)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Autoimmune Adrenocortical Failure
Rescue of Steroidogenic Capacity in Adrenocortical Failure Study (RADS)
This is a pilot study of B lymphocyte depletion therapy in an attempt to salvage adrenal steroidogenic capacity in ten subjects with early autoimmune Addison's disease.
- Trial name
- RADS (NCT00753597)
- Testing
- Solu-medrone, Mabthera
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Newcastle University
Disorders of Sex Development, Congenital Adrenal Hyperplasia
Gene Polymorphisms Influencing Steroid Synthesis and Action
The extend of steroid biosynthesis and action is mainly dependent on underlying genetic polymorphisms and gene mutations. These sequence variations in multiple genes involved in steroid biosynthesis and action cause different…
- Conditions
- Disorders of Sex Development, Congenital Adrenal Hyperplasia, Congenital Adrenal Hypoplasia, Adrenal Insufficiency
- Trial name
- NCT00485186
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein