Clinical trials: Steroids
Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients
The goal of this randomized clinical trial is to compare the immediate use of steroids after surgery for accelerated discharge in adolescent idiopathic scoliosis and neuromuscular scoliosis after a posterior spinal fusion.
- Trial name
- NCT06023043
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Los Angeles
Eosinophilic Esophagitis
Prospective Multicenter Nationwide Registry of Children With Eosinophilic Esophagitis
1. Registry of demographic, clinical, endoscopic and histological data at baseline. 2. Registry of patients treated with PPI: Clinical, endoscopic and histological response at 8-12 weeks of induction treatment Clinical…
- Trial name
- RENESE (NCT03858426)
- Testing
- no intervention
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Sociedad Espanola de Gastroenterologia, Hepatologia y Nutricion Pediatrica
End-Stage Renal Disease
Steroid Withdrawal in Pediatric Kidney Transplant Recipients
The purpose of this study is to examine the effects of withdrawing steroids on graft rejection and kidney functions in kidney transplant recipients between the ages of 0 and 20 years (prior to their 21st birthday).
- Trial name
- NCT00023244
- Testing
- Basiliximab, Cyclosporine, Tacrolimus
- Where
- 19 sites in United States, Mexico
- Volunteers
- 274 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hepatitis
Severe Hepatitis Intervention With Emapalumab for Liver Disease
The goal of this study is to see whether a medicine called emapalumab, a monoclonal antibody, is safe and works well for patients aged 1 year and older who have indeterminate severe hepatitis with T-cell activation and have not…
- Trial name
- SHIELD (NCT07744919)
- Testing
- Emapalumab
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Healthcare of Atlanta
Nephrosis, Focal Lipoid Glomerulosclerosis
Steroid Treatment for Kidney Disease
Focal segmental glomerulosclerosis (FSGS) and minimal change disease are kidney diseases that are associated with increased excretion of protein in the urine.
- Trial name
- NCT00065611
- Testing
- Oral dexamethasone
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Nephrotic Syndrome
Rituximab in Multirelapsing Minimal Change Disease (MCD) or Focal Segmental Glomerulosclerosis (FSGS)
Background. Patients, especially children, with steroid-dependent or multirelapsing nephrotic syndrome (NS) secondary to minimal change disease (MCD) or idiopathic focal and segmental glomerulosclerosis (FSGS) on continuous…
- Trial name
- NEMO (NCT00981838)
- Testing
- Rituximab
- Where
- 7 sites in Italy
- Volunteers
- 24 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pregnancy, Respiratory Distress Syndrome
Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
This is a randomized placebo controlled trial to evaluate whether antenatal corticosteroids can decrease the rate of neonatal respiratory support, thus decreasing the rate of NICU admissions and improving short-term outcomes in…
- Conditions
- Pregnancy, Respiratory Distress Syndrome, Pregnancy Outcomes, Preterm Birth
- Trial name
- ALPS (NCT01222247)
- Testing
- Betamethasone
- Where
- 17 sites in United States
- Volunteers
- 2,831 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center