Clinical trials: Sting
Complex Congenital Heart Defect, Dysfunctional RVOT Conduit
COMPASSION S3 Post-Approval Study
This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve…
- Conditions
- Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
- Trial name
- NCT04860765
- Testing
- SAPIEN 3 THV
- Where
- 19 sites in United States
- Volunteers
- 150 people
- Sponsor
- Edwards Lifesciences
Poisoning by Scorpion Sting
A Trial of Equine F (ab')2 Antivenom for Treatment of Scorpion Envenomation in Morocco
This study has the objective to demonstrate the effectiveness of Alacramyn NAMO in the treatment of North Africa and Middle East scorpions envenomation by reducing the severity of envenomation.
- Trial name
- NCT01336660
- Testing
- Equine F(ab')2 antivenom
- Where
- 2 sites in Morocco
- Volunteers
- 56 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Scorpion Sting
Open Label Clinical Trial of Anascorp® in Pediatric Patients With Scorpion Sting Envenomation
There is no FDA approved therapy for the treatment of scorpion envenomation. Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening.
- Trial name
- NCT01599936
- Testing
- Anascorp
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Allergy, Insect Venom, Allergy Insect Stinging
Immunotherapy for the Treatment of Hymenoptera Venom Allergy in Real-life Conditions.
Observational clinical follow-up to evaluate the safety of immunotherapy for the treatment of hymenoptera venom allergy in real-life conditions. It includes the evaluation of controlled and spontaneous stings.
- Conditions
- Allergy, Insect Venom, Allergy Insect Stinging, Insect Sting Allergy
- Trial name
- Venox-23 (NCT06790368)
- Testing
- VENOX
- Where
- 3 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Inmunotek S.L.
Obstruction; Airway, With Asthma
Impedance Pneumography Measurement During Acute Airway Obstruction and Recovery Phase in Young Children
The purpose of this study is to evaluate the association of signals recorded and analysed with Ventica® LFTS in infants and preschoolers during acute airway obstruction/asthma exacerbation and recovery thereof for changes in the…
- Trial name
- NCT03488303
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- Revenio Research
Mechanical Ventilation, Pneumonia
Removal of Endotracheal Tube Secretions Comprehensively Until Extubation
The purpose of this study is to measure secretion accumulation within endotracheal tubes of mechanically ventilated patients and test the efficacy, safety and clinical impact of removing the secretions using novel airway…
- Trial name
- RESCUE (NCT00663637)
- Testing
- CAM (Complete Airway Management) Catheters
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- O. M. Neotech, Inc.
Scorpion Sting Envenomation
Establishment of Natural History of Scorpion Envenomation
This retrospective study was conducted to collect data from approximately 100 patients from 6 months to 18 years of age who were stung by a scorpion but were not treated with antivenom.
- Trial name
- NCT00696683
- Testing
- None, this is an observational study
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Allergy, Insect Venom, Allergy Insect Stinging
Prospective Observational Study to Evaluate the Safety of Immunotherapy as a Treatment for Hymenoptera Venom Allergy
Observational study to evaluate the safety of immunotherapy as a treatment for Hymenoptera venom allergy, analyzing the adverse reaction to immunotherapy as well as the allergic reaction to a spontaneous hymenoptera sting.
- Conditions
- Allergy, Insect Venom, Allergy Insect Stinging, Insect Sting Allergy
- Trial name
- NCT06782217
- Testing
- VENOX
- Where
- 9 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Inmunotek S.L.
Snake Bite
Study to Evaluate the Efficacy of Two Treatment Schemes With Antivipmyn ® for the Treatment of Snake Bite Envenomation
The purpose of this study is to compare whether a same total dose given up front as a single dose is more effective and as safe as the same dose given as a fractioned dose.
- Trial name
- NCT00639951
- Testing
- A, Antivipmyn ®
- Where
- 5 sites in Mexico
- Volunteers
- 10 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Scorpion Envenomation
AScVS and/ or Prazosin for Scorpion Envenomation
The data available for the efficacy of AScVS and prazosin is generated through different trials done in different clinical setting.
- Trial name
- NCT00753064
- Testing
- Antiscorpion venom serum(AScVS)., T.Prazosin, AScVS + Prazosin
- Where
- 5 sites in India
- Volunteers
- 81 people
- Sponsor
- Haffkine Bio-Pharmaceutical Corporation Ltd.
Arachnidism, Latrodectism
The Efficacy and Safety of Aracmyn in Patients With Systemic Latrodectism
The purpose of this study is to compare the safety and effectiveness of an investigational antivenom and the current standard of care (pain management with opioid analgesics) for treating patients with a widow spider bite.
- Trial name
- NCT00247078
- Testing
- widow spider antivenom
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Snake Bite
Phase 3 Multicenter Comparative Study to Confirm Safety and Effectiveness of the F(ab)2 Antivenom Anavip.
The purpose of this study is to establish if F(ab)2 antivenom (Anavip) is safe for crotalinae envenomation. Confirm its effectiveness in preventing the occurrence of delayed coagulopathies and compare the safety and efficacy with…
- Trial name
- NCT00636116
- Testing
- Crotalinae (pit viper) equine immune F(ab)2, Crotalidae Polyvalent Immune Fab, ovine
- Where
- 18 sites in United States
- Volunteers
- 121 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Snake Bites, Antivenins
Evaluation of Anti-venoms Serum in Africa
There is little or no assessment under real-use conditions of the efficacy and the tolerance in the short, medium and long term of the antivenoms currently on the market and used in the treatment of snake bites.
- Conditions
- Snake Bites, Antivenins, Snake Venoms
- Trial name
- ESAA (NCT03326492)
- Testing
- Antivenom serum Inoserp Pan-Africa® injection
- Where
- 13 sites in Cameroon
- Volunteers
- 474 people
- Sponsor
- Institut Pasteur
Scorpion Sting Envenomation
Double-Blind, Alacramyn® vs. Placebo in Pediatric Patients
There is no FDA approved therapy for the treatment of scorpion envenomation, Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening.
- Trial name
- NCT00685230
- Testing
- Antivenin Centruroides (scorpion) equine immune F(ab)2
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Scorpion Sting Envenomation
Treatment Protocol for Use of Anascorp™ in Patients With Scorpion Sting Envenomation
This treatment protocol will enable therapeutic use of Anascorp in the management of systemic manifestations of scorpion sting envenomation, in patients for whom antivenom would otherwise be unavailable.
- Trial name
- NCT00624078
- Testing
- Antivenin Centruroides (scorpion) F(ab)2 Anascorp™
- Where
- 18 sites in United States
- Volunteers
- 1,426 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Latrodectism
Black Widow Spider Antivenin for Patients With Systemic Latrodectism
The purpose of this study is to test the efficacy and safety of a new antivenom called Analatro® for treating black widow spider bites in patients who present to a hospital emergency room within 24 hours of symptom onset.
- Trial name
- BWSP3 (NCT00657540)
- Testing
- Analatro, Saline
- Where
- 16 sites in United States
- Volunteers
- 60 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Nakajo-Nishimura Syndrome, Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature Syndrome
A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS
The main purpose of this study is to evaluate the efficacy and safety of baricitinib in adult and pediatric Japanese participants with Nakajo-Nishimura Syndrome/chronic atypical neutrophilic dermatosis with lipodystrophy and…
- Conditions
- Nakajo-Nishimura Syndrome, Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature Syndrome, STING-Associated Vasculopathy With Onset in Infancy, Aicardi Goutieres Syndrome
- Trial name
- NCT04517253
- Testing
- Baricitinib
- Where
- 5 sites in Japan
- Volunteers
- 10 people
- Sponsor
- Eli Lilly and Company
Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM)
Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes
The Requesting Physician/Investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.
- Conditions
- Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM), Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI), Aicardi-Goutières Syndrome (AGS)
- Trial name
- NCT01724580
- Testing
- Baricitinib
- Where
- 3 sites in United States, United Kingdom
- Sponsor
- Eli Lilly and Company
Insect Bites
Comparative Study of Two Forms of Topical Dexchlorpheniramine Maleate (Cream Versus Gel) for Insect Bites
Insect bite related symptoms (pruritus and papules) are caused by the release of histamine by mast cells in the skin. Topical anti-histaminics can be used to promote relief of these symptoms.
- Trial name
- NCT01233934
- Testing
- Dexchlorpheniramine 1% Gel, Dexchlorpheniramine 1% Cream
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.
Insect Bites
Non-inferiority Clinical Trial of Dexchlorpheniramine (Cream Versus Lotion) in the Relief of Insect Bite Related Symptoms
Insect bite related symptoms (pruritus and papules) are caused by the release of histamine by mast cells in the skin. Topical anti-histaminics can be used to promote relief of these symptoms.
- Trial name
- NCT00995397
- Testing
- Dexchlorpheniramine 1% lotion, Dexchlorpheniramine 1% cream
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.