Clinical trials: Stool
Food Intolerance
Washed Microbiota Transplantation for Food Intolerance
Food intolerance (FI) is an adverse reaction to food caused by non-immune mechanisms, mainly related to digestive enzyme deficiencies (e.g. lactase deficiency), metabolic abnormalities (e.g.
- Trial name
- NCT07190183
- Testing
- washed microbiota transplantation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Colorectal Cancer, Colon Polyp
Colorectal Cancer Screening Using Stool DNA-based SDC2 Methylation Test
A study of colorectal cancer screening using stool DNA-based SDC2 methylation test
- Conditions
- Colorectal Cancer, Colon Polyp, Healthy
- Trial name
- NCT04304131
- Testing
- Earlytect Colon Cancer
- Where
- 8 sites in South Korea
- Volunteers
- 1,210 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Tuberculosis
Evaluation of Four Stool Processing Methods Combined With Xpert MTB/RIF Ultra for Diagnosis of Intrathoracic Paediatric TB (TB-Speed - Stool Processing)
There is a growing interest for the use of stool samples as an alternative to respiratory samples for the diagnosis of intrathoracic TB in children unable to produce sputum.
- Trial name
- NCT04203628
- Testing
- Xpert MTB/Rif Ultra on stool samples, Xpert MTB/Rif Ultra on respiratory sample
- Where
- 3 sites in Uganda, Zambia
- Volunteers
- 215 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Fecal Incontinence
Transcutaneous Posterior Nerve Stimulation inTreatment of Fecal Incontience
Shafik and colleagues were the first to report the use of posterior tibial nerve stimulation (PTNS) for FI, and they documented improved continence after 4 weeks course.
- Trial name
- NCT04478799
- Testing
- Transcutanous Posterior Tibial Nerve Stimulation
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Batterjee Medical College
Malignant Hematologic Neoplasm
Fecal Microbiota Transplantation Among Adult Patients With Hematological Malignancies
In Hungary - in comparison to other member states of the European Union - about 75000 new cases of cancer are diagnosed annually, from which approximately 4500-5000 patients suffer from so-called malignant hematological diseases.
- Trial name
- HEMAT-FMT (NCT07172191)
- Testing
- Fecal Microbial Transplantation
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Del-Pest Central Hospital - National Institute of Hematology and Infectious Diseases
Inflammatory Bowel Disease, Ulcerative Colitis
Standardized Fecal Microbiota Transplantation for Inflammatory Bowel Disease
There are many limitations in the current treatments of Inflammatory bowel disease (IBD). Now the investigators realized that the intestinal microecological is closely associated with the development of IBD.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease
- Trial name
- SFMT-IBD (NCT02335281)
- Testing
- FMT, Mesalazine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Yanling Wei
Fecal Impaction, Lower Urinary Tract Disorder
Development of Fecal Scoring for the Management of Fecal Impaction With Regards to Lower Urinary Tract Dysfunction
The role of bowel bladder disorder, or BBD, has been highlighted as a major player in vesicoureteral reflux and urinary tract infection (UTI).
- Conditions
- Fecal Impaction, Lower Urinary Tract Disorder, Bladder Dysfunction, Bowel Dysfunction
- Trial name
- NCT04579731
- Testing
- Lactitol Monohydrate
- Where
- South Korea
- Volunteers
- 187 people
- Sponsor
- Seoul National University Hospital
Obesity, Childhood
GI Tract Biomarkers in Infants With Different Diets
Childhood obesity is increasing with more than one-third of adolescents currently overweight and one in five with obesity. The lifelong incidence of obesity-related morbidities is also increasing with childhood obesity.
- Trial name
- NCT03751137
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Chronic Pancreatitis, Pancreatic Exocrine Insufficiency
Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function Tests
The goal of this observational study is to improve the epidemiological data of pancreatic exocrine insufficiency in China, determine the FE-1 cut-off value for the classification of PEI, and explore the characteristic differences…
- Conditions
- Chronic Pancreatitis, Pancreatic Exocrine Insufficiency, Diabetes Mellitus, Community Populations
- Trial name
- NCT06006312
- Testing
- fecal elastase-1 test, 72-hour fecal fat quantification, blood sample test
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Celiac Disease, Gluten Sensitivity
Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac Disease
This study aims to investigate how knowledge of gluten immunogenic peptide (GIP) levels in stool and urine affects subsequent adherence to a gluten-free diet.
- Conditions
- Celiac Disease, Gluten Sensitivity, Gluten Enteropathy, Gastrointestinal Disease
- Trial name
- NCT03462979
- Testing
- Immunochromatographic lateral flow test
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Functional Gastrointestinal Disorders
Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders
Safety and efficacy of FMT in Pediatric Functional Gastrointestinal Disorders
- Trial name
- FGIDs (NCT05753774)
- Testing
- FMT, Conventional drugs
- Where
- China
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Biao Zou
Fecal Incontinence
Effect of Anorectal Biofeedback on Encopresis in School Aged Girls After Sexual Assault
Females who have been sexually abused anally, have a disturbed anorectal motility. They have an increased resting pressure at the lower part of the anal canal.
- Trial name
- NCT04652024
- Testing
- Anorectal manometry
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Badr University
Chronic Constipation
Movicol in Childhood Constipation (ProMotion Study)
This was a single centre study comprised of two stages (Parts I and II). Part II was a 12 week randomised double blind comparison of Movicol and Lactulose Dry as maintenance therapy on an out-patient basis.
- Trial name
- NCT00404040
- Testing
- Polyethylene glycol 3350 NA bicarbonate NaCl KCl (Movicol), Lactulose
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Norgine
Perforated Diverticulitis
Characteristics of Abdominal Fluid in Patients With Diverticulitis Hinchey III or IV
Perforated diverticulitis of the colon can be complicated by peritonitis, either purulent or fecal. Both are life threatening conditions requiring emergency surgery.
- Trial name
- NCT04427891
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
FPIES
Longitudinal Study of the Intestinal, Cutaneous and Salivary Microbiota in Children With Food-induced Enterocolitis Syndrome (SEIPA)
Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non IgE-mediated allergy, presenting with vomiting, and may be complicated by hypovolemic shock.
- Trial name
- SEIBIOTE (NCT04081415)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fecal Microbiota Transplantation in GVHD
Fecal Microbiota Transplantation for Treatment of Refractory Graft Versus Host Disease-a Pilot Study
The study evaluates safety and efficacy of fecal microbiota transplantation (FMT) for the treatment of refractory graft-versus-host-disease (GVHD) of the gut.
- Trial name
- NCT03549676
- Testing
- Fecal Microbiota Transplantation
- Volunteers
- 15 people
- Sponsor
- Shanghai Children's Medical Center
Constipation
Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen
This study will evaluate changes in the fecal microbiome in constipated pediatric patients before and after antegrade continence enema placement and initiation of antegrade enema flushes.
- Trial name
- NCT05821309
- Testing
- PEG 3350, PEG-3350 with electrolytes, Glycerin
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autism Spectrum Disorder (ASD), Gastro-Intestinal Disorder
The Gut-Brain Study
The purpose of this study is to find out if transplant of fecal matter (stool), also known as fecal microbiota transplantation (FMT), from a healthy person into the intestines of children and young adults with Autism Spectrum…
- Trial name
- NCT03426826
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Los Angeles
Autism Spectrum Disorder, Autism
Efficacy, Safety, and Tolerability Study of Oral Full-Spectrum MicrobiotaTM (CP101) in Subjects With Autism Spectrum Disorder and Associated GI Symptoms (SPROUT)
Adolescent autism spectrum disorder subjects with associated GI symptoms will be randomized to receive oral dosing of CP101 capsules in Treatment Group I or matching placebo capsules in Treatment Group II.
- Conditions
- Autism Spectrum Disorder, Autism, ASD, Autistic Thinking
- Trial name
- SPROUT (NCT03829878)
- Testing
- CP101
- Sponsor
- Finch Research and Development LLC.
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi