Clinical trials: Strabismus, Divergent
Exotropia Intermittent
Using Dichoptic Therapy to Treat Intermittent Exotropia
Intermittent exotropia is difficult to treat. The mainstay of treatment involves surgery, and in one long-term study authors found that as many as 60% of IXT required at least one re-operation.Patching of the non-dominant eye has…
- Trial name
- NCT06529016
- Testing
- Luminopia, a virtual reality headset, Paper pre- survey, Paper Survey
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Virginia Commonwealth University
Primary Exotropia, Strabismus
Accommodative Changes After Medial Rectus Resection Versus Plication in Primary Exotropia
Exotropia is a type of eye misalignment in which one eye turns outward. In some patients, surgery is needed to improve eye alignment and binocular function.
- Conditions
- Primary Exotropia, Strabismus, Strabismus Surgery, Exotropia
- Trial name
- NCT07637253
- Testing
- Lateral Rectus Recession combined with Medial Rectus Resection, Lateral Rectus Recession combined with Medial Rectus Plication
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Exotropia, Evaluation of Surgical Techniques in Correcting Exotropia
Evaluation of The Techniques in Correcting Large-Angle Exotropia
The aim of this study is to evaluate the techniques of combined lateral rectus muscle recession with hang back and combined lateral rectus muscle recession with z-tenotomy in correcting large-angle exotropia.
- Trial name
- NCT06084442
- Testing
- Evaluation of The Techniques of Lateral Rectus Muscle Combined Recession with Hang Back and Combined Recession with Z-Tenotomy in Correcting Large-Angle Exotropia
- Volunteers
- 50 people
- Sponsor
- Tanta University
Intermittent Exotropia
Part-time Patch Therapy for Treatment of Intermittent Exotropia
Intermittent exotropia is the most common type of exotropia in children. Treatment options are surgical and non surgical. Nonsurgical management include Correction of refractive errors, Active orthoptic treatments, Prisms and…
- Trial name
- NCT03700632
- Testing
- patch therapy
- Volunteers
- 64 people
- Sponsor
- Tehran University of Medical Sciences
Intermittent Exotropia
Early Results of Slanted Recession of the Lateral Rectus Muscle for Intermittent Exotropia With Convergence Weakness
This study was conducted to evaluate results of slanted recession of the lateral rectus muscle for intermittent exotropia with convergence weakness
- Trial name
- NCT02131792
- Testing
- Slanted recession of the lateral rectus muscle
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Kyungpook National University Hospital
Exotropia, Exophoria
A-eyedrops on Ocular Alignment and Binocular Vision
Atropine is a non-selective muscarinic acetylcholine (M) receptor antagonist that paralyzes the ciliary muscle, dilates the pupil, and reduces the power of accommodation.
- Conditions
- Exotropia, Exophoria, Myopia
- Trial name
- NCT05379855
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops
- Where
- China
- Volunteers
- 339 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Surgical Correction, V Pattern
Surgical Correction of V Pattern Intermittent Exotropia Without Inferior Oblique Muscle Overaction
Evaluation of the results of surgical correction of V pattern intermittent exotropia without inferior oblique muscle overaction by either performing bilateral lateral rectus recession (BLR) alone or performing bilateral lateral…
- Conditions
- Surgical Correction, V Pattern, Intermittent Exotropia, Inferior Oblique Muscle
- Trial name
- NCT07180199
- Testing
- Bilateral Lateral Rectus Recession (BLR Recession), Bilateral Lateral Rectus Recession with Upward Transposition
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Exotropia
Comparative Study of Muscle Transplantation Versus Y Splitting Recession Technique in Treatment of Large Angle Exotropia
This study is designed to correct large-angle exotropia by monocular surgery. It compares two augmented recession techniques, which are recession with muscle transplantation and recession with Y splitting.
- Trial name
- NCT07350330
- Testing
- muscle transplantation, Y splitting
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Intermittent Exotropia
Office Based Vergence/Accommodative Therapy for the Treatment of Intermittent Exotropia
Effectiveness of office based vergence/accommodative therapy for the treatment of intermittent exotropia is investigated through a randomized clinical trial
- Trial name
- NCT04744779
- Testing
- Office-based accommodative/vergence therapy and home reinforcement
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Intermittent Exotropia, Exercises
The Effect of Oculo-Motor Exercises in Intermittent Exotropia
In childhood strabismus, exotropia is most frequently seen with intermittent exotropia and convergence failure in the first decade of life.
- Trial name
- NCT03661476
- Testing
- Oculo-Motor Exercises (OME)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Medipol University
Exotropia Intermittent
Base-in Prism Spectacles for Intermittent Exotropia
The objective of this short-term, pilot randomized trial comparing spectacles with relieving prism to spectacles without prism is to determine whether to proceed to a full-scale, longer-term randomized trial.
- Trial name
- IXT6 (NCT03998670)
- Testing
- Prism Glasses, Non-Prism Glasses
- Where
- 28 sites in United States
- Volunteers
- 61 people
- Sponsor
- Jaeb Center for Health Research
Strabismus, Esotropia
Bupivacaine Injection of Eye Muscles to Treat Strabismus
This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus.
- Conditions
- Strabismus, Esotropia, Exotropia, Graves Disease
- Trial name
- NCT01616108
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Smith-Kettlewell Eye Research Institute
Intermittent Exotropia, Strabismus
The Analysis of Ocular Deviations Between Dominant and Non-dominant Eye Using Video-oculography (VOG) in Intermittent Exotropia
Fifteen subjects with intermittent exotropia were included. The subjects were asked to fixate on a black-on-white optotype at 1 m, which subtended a visual angle of 50 min of arc, equating to a Snellen optotype of 20/200.
- Trial name
- NCT03641040
- Testing
- Video-oculography, Alternative prism cover test
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Inje University
Intermittent Exotropia
Improving Control of Intermittent Exotropia
To determine whether use of dichoptic movies for 8 weeks may be helpful in improving control alignment in children with intermittent exotropia (IXT), thus allowing IXT to be managed non-surgically
- Trial name
- NCT07272005
- Testing
- dichoptic videos, standard videos
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Retina Foundation of the Southwest
Intermittent Exotropia
Trial of Vision Therapy for Intermittent Exotropia
The main objective of this randomized trial comparing vision therapy to observation is to determine the short-term effectiveness of vision therapy on distance intermittent exotropia control.
- Trial name
- VT-IXT (NCT04487249)
- Testing
- Vision Therapy
- Where
- 6 sites in United States
- Volunteers
- 47 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Moderate Intermittent Exotropia
Study of Surgical Treatment Versus Observation in Children With Moderate Intermittent Exotropia
The purpose of this study is to determine the long-term effect and security of the surgical treatment and observation only on ocular alignment, binocular stereopsis, and quality of life in children with moderate intermittent…
- Trial name
- SOMIX (NCT02736526)
- Testing
- recession or resection of the horizontal extraocular muscles
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sun Yat-sen University
Dynamic Stereopsis in Intermittent Exotropia Patients
A Novel Dynamic Random-dot Stereopsis Assessment to Measure the Stereopsis in Intermittent Exotropia
A novel dynamic random-dot stereopsis test that included motion + disparity (MD), motion (M), and disparity (D), in which the disparity cues range from 200 to 1200 arc-seconds was used.
- Trial name
- NCT04152122
- Testing
- The dynamic stereopsis test
- Where
- China
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Strabismus, Esotropia
Risk Factors And Surgical Outcomes Of Strabismus Reoperation
Horizontal strabismus, commonly known as inward or outward deviation of the eyes, is a frequent eye condition that may require surgical correction.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- RSOR (NCT07446621)
- Testing
- Horizontal Strabismus Reoperation
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Exotropia
Observation Versus Occlusion Therapy for Intermittent Exotropia
The present study is being conducted to assess the natural history of intermittent exotropia and to establish the effectiveness of occlusion in its treatment.
- Trial name
- IXT2 (NCT01032330)
- Testing
- occlusion treatment
- Where
- 2 sites in United States
- Volunteers
- 611 people
- Sponsor
- Jaeb Center for Health Research
Intermittent Exotropia
Full-Time Occlusion Therapy for Intermittent Exotropia in Children
Determine whether full-time patching is more effective than observation for improving distance control of IXT after 3 months of treatment (on-treatment outcome).
- Trial name
- IXT7 (NCT05462821)
- Testing
- Eye Patch
- Where
- 25 sites in United States
- Volunteers
- 73 people
- Sponsor
- Jaeb Center for Health Research