Clinical trials: Strabismus, Divergent
Exotropia
Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent Exotropia
The purpose of this study is to evaluate the effectiveness of bilateral lateral rectus muscle recession versus unilateral lateral rectus recession with medial rectus resection procedures for the treatment of basic type and pseudo…
- Trial name
- IXT1 (NCT01032603)
- Testing
- Bilateral lateral rectus recession (BLRc), Unilateral lateral rectus recession with medial rectus resection (R&R)
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- Jaeb Center for Health Research
Strabismus, Divergent
Lateral Rectus Muscle Strangulation in Cases of Exotropia
The goal of our study to evaluate effect of lateral rectus muscle strangulation as a novel effective weakening technique in cases of exotropia.
- Trial name
- NCT07373197
- Testing
- Muscle strangulation
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Sohag University
Exotropia
Observation Versus Occlusion Therapy for Intermittent Exotropia
The present study is being conducted to assess the natural history of intermittent exotropia and to establish the effectiveness of occlusion in its treatment.
- Trial name
- IXT2 (NCT01032330)
- Testing
- occlusion treatment
- Where
- 2 sites in United States
- Volunteers
- 611 people
- Sponsor
- Jaeb Center for Health Research
Intermittent Exotropia, Strabismus
The Analysis of Ocular Deviations Between Dominant and Non-dominant Eye Using Video-oculography (VOG) in Intermittent Exotropia
Fifteen subjects with intermittent exotropia were included. The subjects were asked to fixate on a black-on-white optotype at 1 m, which subtended a visual angle of 50 min of arc, equating to a Snellen optotype of 20/200.
- Trial name
- NCT03641040
- Testing
- Video-oculography, Alternative prism cover test
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Inje University
Intermittent Exotropia
Trial of Vision Therapy for Intermittent Exotropia
The main objective of this randomized trial comparing vision therapy to observation is to determine the short-term effectiveness of vision therapy on distance intermittent exotropia control.
- Trial name
- VT-IXT (NCT04487249)
- Testing
- Vision Therapy
- Where
- 6 sites in United States
- Volunteers
- 47 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Large Angle Exotropia
True Muscle Transplantation Surgery Versus Augmented Semi Hang Back Recession in Large Angle Exotropia: Evaluation of Efficacy and Lateral Gaze Incomitance
This a randomized clinical trial comparing True muscle transplantation surgery versus Augmented Semi hang back recession for treatment of large angle exotropia
- Trial name
- NCT07784842
- Testing
- True Muscle Transplantation Surgery, Augmented Semi hang back Recession
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Hassnaa Mohamed Abdelhameed Ahmed
Intermittent Exotropia
Study of Non-surgical Treatment Versus Observation in Asian Children With Intermittent Exotropia
Non-surgical treatment (ie. patching or fusion exercises) of intermittent exotropia may help in increasing control of strabismus
- Trial name
- NCT01267500
- Testing
- Non surgical therapy
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Intermittent Exotropia
Near Vergence Training for Distance Control in Intermittent Exotropia
Intermittent Exotropia (IXT) is a common type of eye misalignment where one eye periodically turns outward, and control is typically much worse when looking at objects far away than close up.
- Trial name
- NCT07642687
- Testing
- Home-based near eye training program
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The Hong Kong Polytechnic University
Exotropia Equal or More Than 50 Prism Diopter
A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia
This is a randomized comparative interventional study that aims to compare the surgical outcomes of correcting large angle exotropia (≥50 prism diopter) by three different surgical techniques including: 1/ bilateral lateral…
- Trial name
- NCT07143032
- Testing
- Extropia squint surgery
- Volunteers
- 60 people
- Sponsor
- Sohag University
Intermittent Exotropia
Trial of Overminus Spectacle Therapy for Intermittent Exotropia
The main objectives of this randomized trial comparing overminus lens treatment to non-overminus (spectacles without overminus or spectacles with plano lenses) are to determine: The long-term on-treatment effect of overminus…
- Trial name
- IXT5 (NCT02807350)
- Testing
- Overminus treatment, Non-overminus treatment
- Where
- 61 sites in United States, Canada
- Volunteers
- 386 people
- Sponsor
- Jaeb Center for Health Research
Intermittent Exotropia
Visual Perceptual Learning Based Digital Therapeutics for Stereopsis in Intermittent Exotropia
This study evaluates the efficacy and safety of visual perceptual learning for improving stereopsis in intermittent exotropia. Half of participants will receive visual perceptual training using the Nu.T.
- Trial name
- NCT06117813
- Testing
- Nu.T, No-Treatment Control
- Where
- 6 sites in South Korea
- Volunteers
- 54 people
- Sponsor
- Nunaps Inc
Intermittent Exotropia
A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia
The objective of this short-term, pilot randomized trial comparing 2.50 diopters (D) overminus lens treatment vs. non-overminus (spectacles without overminus or no spectacles) in children with intermittent exotropia (IXT) 3 to <7…
- Trial name
- IXT3 (NCT02223650)
- Testing
- Overminus treatment, Non-overminus treatment
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Jaeb Center for Health Research
Exotropia
Study of Clinical Types and Surgical Out Come of Pediatric Exotropia
study aiming to evaluate all children presented to strabismus clinic in ophthalmology department at sohag university hospital with divergent squint (exotropia) and to record surgical outcome of those who underwent strabismus…
- Trial name
- NCT05089422
- Testing
- Squint surgery
- Volunteers
- 30 people
- Sponsor
- Sohag University
Intermittent Exotropia
Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT)
•Background and study aims : The investigators conducted this study to evaluate the movement of extraocular muscle after strabismus surgery with non-invasive tool called AS-OCT.
- Trial name
- NCT02383381
- Testing
- lateral rectus recession
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Moderate Intermittent Exotropia
Study of Surgical Treatment Versus Observation in Children With Moderate Intermittent Exotropia
The purpose of this study is to determine the long-term effect and security of the surgical treatment and observation only on ocular alignment, binocular stereopsis, and quality of life in children with moderate intermittent…
- Trial name
- SOMIX (NCT02736526)
- Testing
- recession or resection of the horizontal extraocular muscles
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sun Yat-sen University
Intermittent Exotropia, Exercises
The Effect of Oculo-Motor Exercises in Intermittent Exotropia
In childhood strabismus, exotropia is most frequently seen with intermittent exotropia and convergence failure in the first decade of life.
- Trial name
- NCT03661476
- Testing
- Oculo-Motor Exercises (OME)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Medipol University
Alternating Exotropia
Bil. LR Rec. Using Standard Tables VS Reduced Numbers in Intermittent Exo. in Children Under 6
comparing the motor alignment and the incidence of postoperative esotropia following the correction of intermittent exotropia in children below 7 years by bilateral lateral rectus recession using the standard recession tables…
- Trial name
- NCT04308538
- Testing
- Standard Recession, Reduced Recession
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Exotropia, Exophoria
A-eyedrops on Ocular Alignment and Binocular Vision
Atropine is a non-selective muscarinic acetylcholine (M) receptor antagonist that paralyzes the ciliary muscle, dilates the pupil, and reduces the power of accommodation.
- Conditions
- Exotropia, Exophoria, Myopia
- Trial name
- NCT05379855
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops
- Where
- China
- Volunteers
- 339 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Exotropia
Comparative Study of Muscle Transplantation Versus Y Splitting Recession Technique in Treatment of Large Angle Exotropia
This study is designed to correct large-angle exotropia by monocular surgery. It compares two augmented recession techniques, which are recession with muscle transplantation and recession with Y splitting.
- Trial name
- NCT07350330
- Testing
- muscle transplantation, Y splitting
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Dynamic Stereopsis in Intermittent Exotropia Patients
A Novel Dynamic Random-dot Stereopsis Assessment to Measure the Stereopsis in Intermittent Exotropia
A novel dynamic random-dot stereopsis test that included motion + disparity (MD), motion (M), and disparity (D), in which the disparity cues range from 200 to 1200 arc-seconds was used.
- Trial name
- NCT04152122
- Testing
- The dynamic stereopsis test
- Where
- China
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University