Clinical trials: Substance Abuse Detection
Substance Abuse Detection
Optimizing Toxicological Screening in Drug Endangered Children
Background: Children who enter the foster care system are all too often exposed to illicit drugs in the home. Children from these homes, known as drug endangered children, are not routinely tested for harmful substances.
- Trial name
- NCT01037569
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
HIV, Sexual Risk
Young Women's CoOp Study
The purpose of this study is to test the efficacy of a cultural-, age- and gender-focused Human Immunodeficiency Virus (HIV) prevention intervention in reducing risk behaviors among African-American young women relative to…
- Conditions
- HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse
- Trial name
- YWC (NCT01224184)
- Testing
- Young Women's CoOp, Staying Healthy and Eating Well
- Where
- 2 sites in United States
- Volunteers
- 237 people
- Sponsor
- RTI International
Recurrent CNS Tumors, Brain Cancer
Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors
Background: Primary central nervous system (CNS) tumors grow in the brain and spinal cord. These tumors are rare, but they are difficult to treat and often fatal.
- Conditions
- Recurrent CNS Tumors, Brain Cancer, Gliomas, IDH-wildtype Gliomas
- Trial name
- NCT07374692
- Testing
- SmartMatch testing
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- National Cancer Institute (NCI)
Target Drug-related Adverse Events
Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens
The purpose of this study is to determine whether the addition of selective pharmacogenomic (PGx) testing as determined by Urine Drug Testing (UDT) adds a clinical benefit as evidenced by a reduction in Target Drug-related…
- Trial name
- SPHERE (NCT02625155)
- Testing
- Urine diagnostic testing as SOC, drug regimen changes per SOC, Urine diagnostic testing with selective PGx testing, drug regimen changes based on PGx test results
- Where
- United States
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- InSource Diagnostics
Drug Abuse, Alcohol Abuse
Student Athlete Testing Using Random Notification
The purpose of this study is to determine the influence of drug testing on risk and protective factors of substance abuse among adolescents; examine whether drug and alcohol testing among high school athletes leads to reduced…
- Conditions
- Drug Abuse, Alcohol Abuse, Substance Abuse
- Trial name
- SATURN (NCT00451854)
- Testing
- Random, no advanced notice drug and alcohol testing
- Where
- United States
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
HIV Infections
Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs
The purpose of this study is to evaluate the safety and drug detection of the dapivirine vaginal ring and oral Truvada in breastfeeding mother-infant pairs.
- Trial name
- NCT04140266
- Testing
- Dapivirine (DPV) Vaginal Ring (VR)-004, Truvada Tablet
- Where
- 4 sites in Malawi, South Africa and 2 more
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Sexual Risk
WHC+ (Women's Health CoOp PLUS)
This study compares the effects of standard HIV test, treat and retain (TTR) practices with TTR plus a woman-focused enhanced strategy--Women's Health CoOp (WHC+) intervention) targeting hard-to-reach and vulnerable alcohol and…
- Conditions
- HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse
- Trial name
- NCT01497405
- Testing
- Test, Treat, Retain(TTR) + Women's Health CoOp (WHC), Test, Treat, Retain(TTR) only
- Where
- 2 sites in United States, South Africa
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- RTI International
Glioma, Malignant, Ependymoma
In Vitro Models From Pediatric Brain Tumors
Tumors of the Central Nervous System (CNS) represent the leading cause of cancer-related deaths in children. Current treatment options are not curative for most malignant histologies, and intense preclinical and clinical research…
- Conditions
- Glioma, Malignant, Ependymoma, Medulloblastoma
- Trial name
- PBTS23 (NCT06499636)
- Testing
- other
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bladder Cancer, Kidney Cancer
Ex VIvo DEtermiNed Cancer Therapy
EVIDENT's aim is to test if ex vivo drug screening can predict whether patients with solid cancers will respond, or not respond, to standard care treatments.
- Conditions
- Bladder Cancer, Kidney Cancer, Melanoma, Sarcoma
- Trial name
- EVIDENT (NCT05231655)
- Testing
- Functional drug screen
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust