Clinical trials: Substance Use Disorder
HIV-1-infection
Uganda PrEP and Harm Reduction Evaluation
This is an evaluation of programs to integrate PrEP into existing services for PWUD. PrEP will be delivered according to Uganda national guidelines and data from national monitoring and evaluation forms will be leveraged to…
- Trial name
- NCT05040308
- Testing
- Integrating PrEP delivery
- Where
- Uganda
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Washington
Opioid Use
Prevention Interventions for Opioid Misuse
The purpose of the study is to develop and test innovative interventions to prevent the development of opioid misuse and opioid use disorders among older adolescents and young adults (AYA; ages 16-30) who use opioids, which will…
- Trial name
- NCT04550715
- Testing
- Brief intervention (BI), Portal, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 1,155 people
- Sponsor
- University of Michigan
Alcohol Consumption, Drug Abuse
Self-Selected Brief Alcohol Intervention for Adolescents
Alcohol use among youth continues to be a major concern for this nation, with a large proportion of adolescents increasing their alcohol consumption as they transition from the 6th to the 8th grade.
- Trial name
- NCT00383838
- Testing
- brief, voluntary substance use intervention
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RAND
Adolescent Alcohol Use, Mental Health Issue
Centralized Virtual SBIRT for Pediatric Primary Care
Adolescent alcohol and other drug (AOD) use is a significant public health problem which contributes to high levels of mortality, morbidity and healthcare costs in young people, and identification and early intervention for these…
- Conditions
- Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
- Trial name
- NCT06486688
- Testing
- Centralized Virtual SBIRT
- Where
- United States
- Volunteers
- 22,320 people
- Sponsor
- Kaiser Permanente
Internalizing Disorders, Substance Use Disorders
Family Support Protocol for Adolescent Internalizing Disorders
This R34 will develop and test an adjunctive treatment protocol for addressing co-occurring internalizing disorders among adolescents enrolled in usual care for substance use problems.
- Trial name
- Fam-AID (NCT06413979)
- Testing
- Family Support Protocol for Adolescent Internalizing Disorders (Fam-AID)
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
Initation of Substance Use Disorder
Clinical Screening and Peer Interventions to Prevent Substance Use in At-Risk Adolescents
The goal of this clinical trial is to test a method of preventing substance use among adolescents. Young people aged 11-14 who have depression, anxiety, or attention deficit hyperactivity disorder (ADHD) are at higher than usual…
- Trial name
- NCT07074860
- Testing
- Peer to peer video to raise awareness about substance use
- Volunteers
- 50 people
- Sponsor
- University of Vermont
Opioid Use Disorder (OUD), Chronic Pain
Addiction Treatment in Primary Care Expansion
The Veterans Health Administration (VA) is a national leader in addressing the twin epidemics of chronic pain and opioid use, misuse, and opioid use disorder (OUD); but important challenges remain.
- Trial name
- APEX (NCT03547882)
- Where
- 2 sites in United States
- Sponsor
- VA Office of Research and Development
Psychotic Disorders, Substance Use
Peer Approaches to Substances in Early Psychosis Programs: A Pilot Study of a Peer-Led Intervention
The aim of the study is to pilot a peer-provided, manualized intervention to increase the proportion of young people with first episode psychosis who reduce or stop substance use and improve psychiatric and functional outcomes.
- Trial name
- PAS-EPP (NCT04517279)
- Testing
- Peer Approach to Substances in Early Psychosis Programs, Usual Care Peer Services
- Where
- 15 sites in United States
- Volunteers
- 113 people
- Sponsor
- University of Texas at Austin
Sexually Transmitted Infection, Substance Use
Behavioral Intervention for Minority Adolescent Women
The purpose of this Stage II clinical trial is to test the efficacy of a culturally sensitive, cognitive-behavioral intervention to reduce sexual risk behavior among minority adolescents for prevention of sexually transmitted…
- Conditions
- Sexually Transmitted Infection, Substance Use, Abuse, Pregnancy
- Trial name
- NCT01387646
- Testing
- Project IMAGE
- Where
- United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Opioid Medication Assisted Treatment
Consortium to Disseminate and Understand Implementation of Opioid Use Disorder Treatment
Opioid use disorder (OUD) is a major cause of illness and death among Veterans for which effective treatment is a major priority of the Veterans Health Administration (VHA).
- Trial name
- CONDUIT (NCT04178551)
- Testing
- Implementation Facilitation
- Where
- 11 sites in United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Prescription Drug Abuse (Not Dependent), Substance Use
Preventing Prescription Drug Abuse in Middle School Students
This project is designed to test a primary prevention approach to the problem of prescription drug misuse and abuse (PDA) among middle school students.
- Conditions
- Prescription Drug Abuse (Not Dependent), Substance Use, Substance Abuse
- Trial name
- MSPDA (NCT03129334)
- Testing
- LST Middle School Online
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- National Health Promotion Associates, Inc.
Depression, Dual Diagnosis
Open-Label Creatine Study for Female Meth Users
Study Purposes and Objectives: The objectives should be stated in such a way that the reader can determine the appropriateness of the study design. If appropriate, state the specific hypotheses being tested and/or study aims.
- Conditions
- Depression, Dual Diagnosis, Substance Use
- Trial name
- NCT02189915
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw
Gambling, Alcohol Consumption
Web-based vs In-person Personalized Feedback Intervention for Comorbid Substance Use and Disordered Gambling
Rates of gambling and substance use behaviors are elevated among emerging adults (ages 18-24), and these behaviors are individually and jointly associated with a host of negative consequences.
- Conditions
- Gambling, Alcohol Consumption, Cannabis
- Trial name
- NCT01529047
- Testing
- Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 361 people
- Sponsor
- University of Washington
Vaping, E Cig Use
A Hybrid Program to Prevent Substance Use Risk Among Upper Elementary School Students Using a Positive Youth Development Approach
The goal of this randomized controlled trial is to evaluate a psychosocial school-based hybrid intervention which includes traditional classroom sessions and online e-learning modules to reduce risk of vaping and prescription…
- Conditions
- Vaping, E Cig Use, Prescription Drug Misuse
- Trial name
- NCT07162155
- Testing
- School-based Hybrid Intervention to Prevent Vaping and Prescription Drug Misuse
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Christopher Williams
Fetal Alcohol Spectrum Disorders
Alcohol Use During Pregnancy in Finland According to Meconium Samples
Meconium samples are collected anonymously from newborns in Helsinki University Hospital maternity ward. The study tries to to find how many women continue to use alcohol during the second half of the pregnancy.
- Trial name
- RASMEK21 (NCT04918043)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hanna Kahila
Smoking, Tobacco Use Disorder
QuitAdvisorMD: A Point-of-care Tool for Brief Smoking Cessation Interventions
QuitAdvisorMD: A point-of-care tool for brief smoking cessation interventions Under a Phase II SBIR grant supported by NIH/NIDA, we are developing QUITAdvisorMD: a point-of-care, patient-centered resource for counseling patients…
- Trial name
- NCT01065493
- Testing
- QuitAdvisorMD Software Algorithm, Standard Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Silverchair Science & Communications, LLC
Substance-Related Disorders, Alcohol-Related Disorders
Computer-delivered Psychosocial Intervention for Adolescent Substance Use Disorders
The purpose of this study is to develop and evaluate the acceptability and preliminary efficacy of a web-based, skills training program for adolescents with substance use disorders.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Marijuana Abuse
- Trial name
- NCT00957775
- Testing
- Usual care, Computer-delivered ACRA
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- National Development and Research Institutes, Inc.
Tobacco Use Behavior, Nicotine Dependence Tobacco Product
§SMOKE Nicotine and Tobacco Youth Cohort
The §SMOKE Cohort Study aims to improve understanding of tobacco and nicotine use among adolescents and young adults in Denmark.
- Conditions
- Tobacco Use Behavior, Nicotine Dependence Tobacco Product, E-Cigarette Use, Smoking ( Cigarette)
- Trial name
- NCT07910331
- Where
- Denmark
- Volunteers
- 10,000 people
- Sponsor
- University of Southern Denmark
Substance-Related Disorders
Field Trial of a Relapse Prevention Program for Adolescents Receiving Substance Use Treatment
The purpose of this study is to provide a comprehensive evaluation of the new, Navigating my Journey program for adolescents receiving treatment in an outpatient substance abuse center.
- Trial name
- NCT02125539
- Testing
- Navigating my Journey program, Attention Control
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Inflexxion, Inc.
Adolescent Drinking, Adolescent Problem Behavior
Mindfulness Mobile App to Reduce Adolescent Substance Use
Substance-abusing youth - especially those who are involved in the juvenile justice system - are at higher risk than nonusers for mental health problems, including depression, conduct problems, personality disorders, suicidal…
- Trial name
- Qlarity (NCT04027075)
- Testing
- Qlarity app users
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.