Clinical trials: Sudden Cardiac Arrest
Arrhythmias, Cardiac, Children, Only
Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children
The objective of this project is to evaluate the capability of a specific mobile electrocardiogram monitoring of detecting arrhythmic events in children with history of palpitation and or syncope.
- Conditions
- Arrhythmias, Cardiac, Children, Only, Congenital Heart Disease, Sudden Cardiac Death
- Trial name
- NCT05140343
- Testing
- KARDIA Mobile ECG Monitoring (KMCM)
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Centro Medico Teknon
Sudden Cardiac Death
The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest
Sudden cardiac death (SCD) remains a major cause of mortality within developed nations despite aggressive efforts to reduce its societal burden.
- Trial name
- EPS ARREST (NCT03079414)
- Testing
- Invasive Electrophysiology Study
- Where
- 21 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- Western University, Canada
Cardiac Arrest, Sudden, Ventricular Tachycardia
Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm
In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer…
- Conditions
- Cardiac Arrest, Sudden, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- DEFI-2022 (NCT04691089)
- Where
- France
- Volunteers
- 285 people
- Sponsor
- French Defence Health Service
Myocarditis, Sudden Cardiac Death
Occurrence, Trends, Management and Outcomes of Patients Hospitalized With Myocarditis
The epidemiology of myocarditis is largely unknown and based mainly on small single-center studies. The study aim to evaluate the current incidence, clinical characteristics and outcomes of patients hospitalized due to…
- Conditions
- Myocarditis, Sudden Cardiac Death, Cardiomyopathies, Arrythmia
- Trial name
- MYO-PL (NCT04827706)
- Where
- Poland
- Volunteers
- 19,978 people
- Sponsor
- Medical University of Warsaw
Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation
PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)
The PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE) study is a pilot feasibility trial evaluating the implementation of pre-hospital targeted temperature management (TTM) using a wearable surface…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation, Death, Sudden, Cardiac, Therapeutic Hypothermia
- Trial name
- PRECEDENCE (NCT07421882)
- Testing
- CarbonCool® Cooling Vest
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Sudden Cardiac Death, Cardiac Arrhythmias
Cardiovascular Pre-participation Screening in Children and Adolescents
Sports participation is strongly encouraged in children and adolescents, but intense training at early ages may reveal hidden heart conditions that increase the risk of sudden cardiac death.
- Trial name
- NCT07862504
- Testing
- Pre-participation clinical evaluation, Diagnostic Test: Resting 12-lead electrocardiogram, Diagnostic Test: Step test (Harvard step test)
- Where
- Brazil
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Ventricular Tachycardia, Ventricular Fibrillation
DF4 Connector System Post-Approval Study
The purpose of this study is to evaluate long-term performance of the DF4 Connector System. This evaluation is based on the number of DF4 lead-related complications occurring during the study compared to the number of leads…
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death, Heart Failure
- Trial name
- NCT01638897
- Where
- 78 sites in United States, Canada and 1 more
- Volunteers
- 1,778 people
- Sponsor
- Medtronic
Heart Failure, Sudden Cardiac Death
Longitudinal Surveillance Registry
Boston Scientific CRM's Longitudinal Surveillance Registry (LSR) will serve as an active ongoing source of updated information on the long-term reliability and performance of BSC commercially available leads and LATITUDE-enabled…
- Trial name
- LSR (NCT00636272)
- Volunteers
- 2,500 people
- Sponsor
- Boston Scientific Corporation
Sudden Cardiac Death
S-ICD Implantation: US Based Pilot Study
This trial investigates two key aspects of the S-ICD implantation process. 1) For S-ICD implantation a pre-operative x-ray-based assessment of the anatomy and location of the heart is required.
- Trial name
- SUSTAIN S-ICD (NCT06771700)
- Testing
- Intraoperative PRAETORIAN Score
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Köln
Primary Prevention of Sudden Cardiac Arrest, Secondary Prevention of Sudden Cardiac Arrest
S-ICD® System Post Approval Study
The purpose of the S-ICD Post Approval Study is to document long term safety and effectiveness outcomes associated with the implantation of the SQ-RX pulse generator and Q-TRAK electrode in a commercial clinical setting.
- Trial name
- NCT01736618
- Testing
- S-ICD System
- Where
- 87 sites in United States
- Volunteers
- 1,766 people
- Sponsor
- Boston Scientific Corporation
Sports Accident, Athletes Heart
Lithuanian Atletes' Aortic Diameter
Recent developments in football have seen the sudden death of young football player due to aortic rupture hence reinforcing the controversy of football as a field with substantial risk for sudden cardiac arrest and death.
- Trial name
- NCT03656861
- Testing
- Physical load
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Agne Slapsinskaite
Congenital Heart Disease, Coronary Artery Anomaly
European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries
Anomalous aortic origin of a coronary artery (AAOCA) is a group of rare congenital heart defects with various clinical presentations.
- Conditions
- Congenital Heart Disease, Coronary Artery Anomaly, Sudden Cardiac Death, Surgical Procedure, Unspecified
- Trial name
- EUROAAOCA (NCT06089902)
- Testing
- unroofing or other surgery if needed
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 500 people
- Sponsor
- University of Padova
Inherited Cardiac Arrhythmias, Long QT Syndrome
Long Term Monitoring for Risk of Sudden Death
Risk prediction in in inherited heart rhythm conditions that may cause sudden cardiac arrest or death is difficult. Sometimes the risks may be low but the loss of life in an otherwise healthy young individual is catastrophic.
- Conditions
- Inherited Cardiac Arrhythmias, Long QT Syndrome, Arrhythmogenic Right Ventricular Cardiomyopathy, Brugada Syndrome
- Trial name
- NCT04124237
- Where
- Canada
- Volunteers
- 1,051 people
- Sponsor
- University of British Columbia
Ventricular Tachyarrhythmia, Sudden Cardiac Death
Domperidone and Risk of Serious Cardiac Events in Postpartum Women
The purpose of this study is to determine whether the use of domperidone is associated with an increased risk of serious cardiac events among postpartum women in the six months following delivery.
- Conditions
- Ventricular Tachyarrhythmia, Sudden Cardiac Death, Lactation, Breast Feeding
- Trial name
- NCT04024865
- Testing
- Domperidone, No domperidone
- Where
- Canada
- Volunteers
- 184,929 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Death, Sudden, Cardiac
An Observational Study to Assess the Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Users of Proton Pump Inhibitors, and Users of Metoclopramide
The purpose of this observational study is to assess the risk of out-of-hospital Sudden Cardiac (heart) Death (SCD) associated with current use of domperidone compared to current use of a Proton Pump Inhibitor (PPI), current use…
- Trial name
- NCT01907633
- Testing
- No intervention
- Volunteers
- 15,000 people
- Sponsor
- Janssen Research & Development, LLC
Tetralogy of Fallot, Ventricular Tachycardia
Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot
Individuals with repaired Tetralogy of Fallot (rTOF) remain at risk for sudden cardiac death from ventricular tachycardia (VT). Transcatheter pulmonary valve replacement (TPVR) indications continue to broaden, yet its capability…
- Conditions
- Tetralogy of Fallot, Ventricular Tachycardia, Sudden Cardiac Death
- Trial name
- NCT05236153
- Testing
- Electroanatomic substrate mapping
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Primary Prevention of Sudden Cardiac Arrest, Secondary Prevention of Sudden Cardiac Arrest
Longitudinal Surveillance Study of the 4-SITE Lead/Header System
Post-approval studies of implanted leads provide an opportunity to observe and assess patient outcomes and technology performance in a real-world setting.
- Trial name
- LSS of 4-SITE (NCT01596595)
- Where
- 111 sites in United States, Australia and 1 more
- Volunteers
- 1,820 people
- Sponsor
- Boston Scientific Corporation
Defibrillators, Implantable, Sudden Cardiac Death Due to Cardiac Arrhythmia
French COhoRte Extra-Vascular Implantable CardiovErter DefibrillatoR
Implantable cardioverter-defibrillators (ICDs) are widely recognized for their efficacy in reducing the risk of sudden cardiac death in high-risk patients.
- Trial name
- FOREVER (NCT06739239)
- Testing
- Extra-Vascular Implantable Cardioverter Defibrillator
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Paris Sudden Death Expertise Center
Sudden Cardiac Arrest
HeartStart FRx Defibrillator Event Registry
This post market clinical follow-up study is a multi-center, non-randomized, unblinded, observational registry of the performance of the FRx Automated external defibrillator (AED) used in conjunction with electrodes with or…
- Trial name
- NCT04250857
- Testing
- HeartStart FRX
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Heartstream US LLC
Out-of-Hospital Cardiac Arrest, Death, Sudden, Cardiac
The Use of Mobile Phones in Out of Hospital Cardiac Arrest to Increase Bystander CPR
Death from cardiac disease is one of the most common causes of death in the western world. The majority of these deaths takes place outside hospital as sudden cardiac death.
- Conditions
- Out-of-Hospital Cardiac Arrest, Death, Sudden, Cardiac, Heart Diseases, Ventricular Fibrillation
- Trial name
- RUMBA (NCT01789554)
- Testing
- MLS dispatch for bystander CPR
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Karolinska Institutet