Clinical trials: Sudden Deafness
Vestibular Disorder, Sudden Hearing Loss
Prognosis of Vestibular Dysfunction in Patients With Idiopathic Sudden Sensorineural Hearing Loss
Idiopathic sudden sensorineural hearing loss (ISSNHL) refers to idiopathic sensorineural hearing loss of at least 30 dB over at least three test frequencies occurring over a 72-hour period.
- Trial name
- NCT03951584
- Testing
- ISSNHL with vertigo
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Sudden Hearing Loss
Trans-round Window Membrane Intracochlear Steroid
Safety and efficacy of intracochlear injection of glucocorticoid through the round window membrane in patients with profound or complete sudden sensorineural hearing loss
- Trial name
- NCT07540728
- Testing
- Experimental: Group A: intracochlear triamcinolone acetonide injection, intracochlear injection of dexamethasone, intratympanic dexamethasone injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Hearing Loss, Sudden, Prednisone Acetate
Treatment of Sudden Deafness With Prednisone+Hyperbaric Oxygen and Prednisone+Somatosensory Stimulation
To study the effective treatment of sudden deafness by giving prednisone, hyperbaric oxygen and somatosensory stimulation to sudden deafness patients.
- Conditions
- Hearing Loss, Sudden, Prednisone Acetate, Hyperbaric Oxygen, Somatic Stimulus
- Trial name
- NCT04129983
- Testing
- Drugs and Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Dan Su
Sudden Hearing Loss
Efficacy and Safety of Intracochlear Injection of Glucocorticoid Through the Round Window Membrane in Patients With Profound or Complete Sudden Sensorineural Hearing Loss
Safety and efficacy of intracochlear injection of glucocorticoid through the round window membrane in patients with profound or complete sudden sensorineural hearing loss
- Trial name
- NCT07814677
- Testing
- intracochlear injection of triamcinolone acetonide through the round window membrane, intratympanic dexamethasone injection through the tympanic membrane
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Sudden Loss of Hearing
Bed Rest for Idiopathic Sudden Sensorineural Hearing Loss
sudden sensorineural hearing loss: idiopathic in most cases 5-20/100,000 new cases annually in the U.S no establishes pathogenesis treated with oral steroids in most cases ~50% improvement in hearing levels bed rest - acceptable…
- Trial name
- NCT00416143
- Testing
- bed rest, prednisone - oral corticosteroid 1mg/kg/D for 1 week
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Sensory Hearing Loss, Sensorineural Hearing Loss
The SeaSHeL National Prospective Cohort Study
Each year, approximately 15,000 people in the United Kingdom experience sudden loss of hearing that is sensorineural in nature. In the majority of cases, the cause is unknown despite investigation, and these cases are termed…
- Conditions
- Sensory Hearing Loss, Sensorineural Hearing Loss, Sensorineural Hearing Loss in Left Ear, Sensorineural Hearing Loss in Right Ear
- Trial name
- SeaSHeL (NCT04108598)
- Testing
- Quality of life questionnaire
- Where
- United Kingdom
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- University College, London
Hearing Loss, Sudden, Hearing Loss, Sensorineural
Assessment of The Efficacy of Intratympanic Platelet Rich Plasma for Treatment of Sensorineural Hearing Loss.
Assessment of the efficacy of Intratympanic platelet rich plasma injection for treatment of idiopathic suden sensorineural hearing loss
- Conditions
- Hearing Loss, Sudden, Hearing Loss, Sensorineural, Hearing Loss
- Trial name
- NCT05786378
- Testing
- Platelet Rich Plasma, local anesthesia in external auditory canal, Intratympanic Injection
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Assiut University
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Sensorineural Hearing Loss, Tinnitus
Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing Loss
The HEAR-RESTORE study is an exploratory clinical research program designed to evaluate new diagnostic and regenerative approaches for individuals experiencing inner ear injury, tinnitus, and temporary or permanent hearing loss.
- Conditions
- Sensorineural Hearing Loss, Tinnitus, Acoustic Trauma, Inner Ear Injury
- Trial name
- HEAR-RESTORE (NCT07472023)
- Testing
- Audiologic Monitoring, Investigational Regenerative Pharmacologic Therapy, Stem Cell Regenerative Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Truway Health, Inc.
Sensorineural Hearing Loss, Autoimmune Inner Ear Disease
A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
The purpose of this study is to determine if Anakinra (an interleukin-1 receptor antagonist) can improve hearing thresholds in those patients with Autoimmune Inner Ear Disease (AIED) that did not respond to oral steroid therapy…
- Trial name
- NCT01267994
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Andrea Vambutas
Idiopathic Sudden SNHL
Predictive Factors for Recovery in Idiopathic Sensory Neural Hearing Loss
Sudden sensorineural hearing loss (SSNHL) is an otological emergency that is defined as a hearing loss greater than 30 dB over three consecutive frequencies within 72 hours, with abnormalities of the cochlea, auditory nerve, or…
- Trial name
- NCT05112354
- Testing
- systemic and intratympanic injection of steoid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Sudden Sensorineural Hearing Loss, Hearing Loss, Sensorineural
Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss
The goal of this observational study is to describe the multi-omics characteristics and to learn about the prognostic factors in patients with idiopathic sudden sensorineural hearing loss (SSNHL).
- Conditions
- Sudden Sensorineural Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Sudden
- Trial name
- NCT06365775
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Dan Bing