Clinical trials: Support Persons
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
AI-Supported Therapy for Depression and Anxiety Compared With Standard CBT
This study is a pivotal, randomised, controlled, non-inferiority trial evaluating "Nook," an AI-delivered, neurosymbolic, clinician-supervised digital psychological intervention for depression and anxiety, compared with standard…
- Trial name
- NCT07620340
- Testing
- AI-Digital CBT, Cognitive Behavioural Therapy
- Volunteers
- 400 people
- Sponsor
- PsyScale
Multiple Chronic Conditions
Digitally Supported Person-centered Care Systems
The case history of patients with complex and long-term needs is often stored in fragments across many different care providers, each with a separate electronic health record.
- Trial name
- DignityCare (NCT07142616)
- Testing
- 03 - Summaries of and clinical notes from several providers, 01 - Clinical notes from one provider, 02 - Access to notes from primary and secondary care
- Where
- Norway
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Clinical High Risk for Psychosis (CHR), Suicidal Ideation
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis
Young people at clinical high risk for psychosis are more likely to experience suicide thoughts than the general population, but there are few suicide prevention programs designed specifically for them.
- Conditions
- Clinical High Risk for Psychosis (CHR), Suicidal Ideation, Psychosis, Suicidal Behavior
- Trial name
- NCT07756567
- Testing
- Suicide Prevention Intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder
Early Neurodivergent Developmental Trajectories in Autism and in Response to the ESDM Intervention
Early support is thought to be key to ensure a better quality of life for young children on the autism spectrum. Among early support, different evidence-based approaches have combined the principles of developmental and…
- Trial name
- NCT06494605
- Testing
- Early Start Denver Model (ESDM)
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Skin Condition, Cleft Lip and Palate
Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study
A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns…
- Conditions
- Skin Condition, Cleft Lip and Palate, Burns, Other Conditions Leading to a Visible Difference
- Trial name
- UNGFaceIT (NCT03165331)
- Testing
- Ung Face IT
- Where
- Norway
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Colorectal Polyp
The Accuracy of Human Endoscopic Detection of Submucosal Invasive Cancer in Colorectal Polyps
Colorectal cancer (CRC) is a leading cause of death in the Western world. It can be effectively prevented by removal of pre-malignant polyps (polypectomy) during colonoscopy.
- Trial name
- NCT05191095
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Ghent
Complex Care, Medical Complexity
Complexity in Health, Education, and Social Support for Children and Young People With Life-limiting Conditions.
Children and young people (CYP) with life-limiting conditions represent a growing population with complex care needs that span health, education, and social care systems.
- Conditions
- Complex Care, Medical Complexity, Pediatrics, Life-limiting Illness
- Trial name
- CHESS (NCT07102433)
- Testing
- Children and young people with life-limiting conditions, their parents/carers, and professionals across healthcare, education, and social care sectors.
- Where
- 5 sites in United Kingdom
- Volunteers
- 170 people
- Sponsor
- King's College London
Celiac Disease, Celiac Disease in Children
Supporting Children and Young People to Live Well with Coeliac Disease
Managing a strict gluten-free diet is crucial for children and young people with coeliac disease. However, this can have adverse effects on psychological well-being and quality of life.
- Trial name
- NCT06007898
- Testing
- Parent self-help psychological resource
- Where
- 3 sites in United Kingdom
- Volunteers
- 95 people
- Sponsor
- University of Surrey
Conduct Disorder, Mentalization Based Therapy
Using Mentalization Based Therapy to Support Children and Adolescents Referred to Specialist Mental Health Services in the NHS for Aggressive and/or Violent Behaviour
The MICA Study is a research project that has been designed to work out how helpful mentalisation based therapy is. This is a new type of support that helps young people make sense of their own behaviours and feelings, and those…
- Conditions
- Conduct Disorder, Mentalization Based Therapy, Violent Behavior, Aggressive Behaviour
- Trial name
- MICA (NCT07091721)
- Testing
- Mentalization based therapy (MBT), Support as usual
- Where
- 8 sites in United Kingdom
- Volunteers
- 632 people
- Sponsor
- Anna Freud
Smoking, Psychosis
A Usability Study of a Smoking Cessation Decision Aid in People With a Recent First Episode of Psychosis
The investigators propose to recruit patients who have experienced a recent first episode of psychosis who have a chart diagnosis of Schizophrenia, Schizophrenifom, Schizoaffective Disorder, Psychosis NOS, or Bipolar I Disorder…
- Trial name
- NCT01399112
- Testing
- Web-based computer program
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Northwell Health
Stroke, Stroke Rehabilitation
Volunteer Facilitated Discharge Assistance and Supports at Home (DASH) for People With Stroke
The goal of this clinical trial is to learn if a home visit by a trained volunteer can improve stroke recovery after a stroke survivor is discharged home from the hospital. The main questions it aims to answer are: 1.
- Conditions
- Stroke, Stroke Rehabilitation, Transitional Care
- Trial name
- DASH (NCT07590076)
- Testing
- Discharge Assistance and Supports at Home (DASH)
- Where
- 6 sites in Canada
- Volunteers
- 840 people
- Sponsor
- Bruyère Health Research Institute.
Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation
Taking Out All Teeth and Replacing Them With Dentures That Rest on Implants in People With Type 2 Diabetes
Gum disease and type 2 diabetes are common chronic diseases that affect each other. Diabetes is increasing, especially in Pakistan. People with diabetes have a greater risk for gum disease.
- Conditions
- Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation, Dental Implant Failed
- Trial name
- NCT01774942
- Testing
- Procedure/Surgery
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Traumatic Brain Injury
A Health and Wellness Lifestyle Program to Support Community-Dwelling Persons With Traumatic Brain Injury
To evaluate the efficacy of an adapted telehealth-based, health and wellness lifestyle program on promoting healthy lifestyle behaviors and improving health outcomes.
- Trial name
- POWERS-TBI (NCT04288258)
- Testing
- Telehealth-Based Health and Wellness Program (POWERS-TBI)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Alabama at Birmingham
Insomnia
SleepFix for Youth: Digital Behavioural Therapy for Insomnia With E-Psychologist Support
This pilot randomised, open-label, parallel-group controlled trial will evaluate the feasibility, acceptability and effects of a psychologist-supported digital behavioural therapy for insomnia (dBTi) compared to a wait-listed…
- Trial name
- iSLEEPY (NCT07405775)
- Testing
- SleepFix + e-psychologist support calls, Sleep Health Education (Active control)
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Woolcock Institute of Medical Research
Rett Syndrome
Technology-supported Motor Rehabilitation for People With Rett Syndrome
This study focuses on improving purposeful arm use while simultaneously reducing engagement in stereotypies. It is typically expected that the training period for this study will last about 6 months.
- Trial name
- TeMoRett (NCT07418905)
- Testing
- computer gaming
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Georgetown University
Family Conflict, Family Relations
Parent Web - Support for Families With Young People
To test an online parent training program. Relative to a randomized wait-list control group, those in the Parent Web (PW) will show benefits on well-being, parenting, stress, youth mental health.
- Conditions
- Family Conflict, Family Relations, Family Dysfunction
- Trial name
- PWS2 (NCT06533735)
- Testing
- Parent Web
- Where
- Sweden
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Testicular Cancer, Testis Cancer
Helping Young People With Testicular Cancer Using Virtual and Extended Reality
TRANSCEND-XR is a European research project designed to better support adolescents and young adults who have been cured of testicular cancer.
- Conditions
- Testicular Cancer, Testis Cancer, AYA Cancer Survivors, Survivor Patients
- Trial name
- TRANSCEND-XR (NCT07571499)
- Testing
- Digital tool using extended reality
- Volunteers
- 245 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Unmet Need for Contraception, Uptake of HIV Prevention
Mobile Health Supported Self-care Among Tertiary Education Students in Zimbabwe
Young people of ages 15-24 years, particularly those in Sub-Saharan Africa, do not optimally take up HIV services (HIV testing, HIV prevention and HIV treatment) and contraception.
- Conditions
- Unmet Need for Contraception, Uptake of HIV Prevention, Healthy Participants
- Trial name
- MASCOT (NCT07403318)
- Testing
- MASCOT
- Where
- Zimbabwe
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Arrhythmias
Determination and Comparison of Short-term Effectiveness of Three Methods Used for Recognition of Arrhythmias in People With Different Degrees of Medical Training (Advanced Life Support Workshop Participants-ALS): Randomized Controlled Educational Experiment.
Background: Arrhythmia recognition is a fundamental skill for the provider of advanced life support (ALS). Acquire it is difficult, leading to the birth of systematic methods in an attempt to simplify and optimize, however, it…
- Trial name
- NCT02664779
- Testing
- Arrhythmia diagnosis with the 10 steps method, Arrhythmia diagnosis with the 6 steps method, Arrhythmia diagnosis with the 4 steps method
- Where
- Colombia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Coronary Artery Disease
Decision Support Tool for Revascularisation Options in Coronary Artery Disease
Together with patients and healthcare professionals, we want to design a Decision Support Tool (DST) that will help people with coronary artery disease to understand and choose treatments that best reflect their preferences and…
- Trial name
- DECIDE-CAD (NCT06567626)
- Testing
- Decision Support Tool (DECIDE-CAD)
- Where
- 2 sites in United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Leicester