Clinical trials: Supportive Therapy
Undernutrition, Healthy Nutrition
Women Supporting Women to Improve Infant and Child Feeding Practices
Undernutrition in the first 2 years of life is the largest preventable cause of death before age 5. Among those who survive, stunting before age two leaves millions with lifelong physical and cognitive deficits, which are…
- Conditions
- Undernutrition, Healthy Nutrition, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05473312
- Testing
- Community Sensitization, 28-day PD/Hearth Sessions, Supplemental Print Information
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Aga Khan University
HIV
Evaluation of Use of Clinical Decision Support System in HIV Care in Resource Constrained Settings
The purpose of this study is to determine whether the use of a Computerized Decision Support System (CDSS) in form of alerts to clinicians enhances early detection of immunological treatment failure in HIV patients.
- Trial name
- CDSS (NCT01634802)
- Testing
- EMR Only, EMR+CDSS
- Where
- Kenya
- Volunteers
- 1,460 people
- Sponsor
- Kenya Medical Research Institute
Oral Mucositis Due to Chemotherapy, Hematolymphoid Malignancies
Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid Malignancies
Chemotherapy induced oral mucositis is a common and debilitating complication in pediatric patients receiving chemotherapy for hematolymphoid malignancies.
- Trial name
- BEAM (NCT07605234)
- Testing
- Photobiomodulation Therapy
- Volunteers
- 46 people
- Sponsor
- Tata Memorial Hospital
Emotional States, Therapeutic Communication in Pediatric ICU
Therapeutic Communication Techniques for Children Aged 7-12 in Intensive Care
Summary of the Research Children may need to stay in intensive care for a period of time due to acute or chronic illnesses in their lives.There may be anxiety, fear and concerns in intensive care.
- Conditions
- Emotional States, Therapeutic Communication in Pediatric ICU, Child Emotional Well-being in ICU
- Trial name
- NCT06956586
- Testing
- Therapeutic communication techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uşak University
Pediatric Respiratory Diseases, Asthma
Analysis of Lung Sounds Collected by RESP Biosensor to Support Decision Making in Monitored Hospitalized Pediatric Patients
This observational clinical trial is designed to confirm whether RESP™ Biosensor could be deployed to support clinical decision making in challenging pediatric cases, minimize clinician-to-clinician variability in lung sound…
- Conditions
- Pediatric Respiratory Diseases, Asthma, RSV Infection, COVID-19
- Trial name
- NCT05661422
- Testing
- RESP™ Biosensor
- Where
- United States
- Sponsor
- Strados Labs, Inc.
Performance Enhancement, Supportive Care
Effects of Wrestling Training on Psychological Well-Being, Anxiety, and Resilience in Adolescent Sedanter Boys
This randomized controlled study investigated the psychological effects of a six-week, non-competitive wrestling training program in sedentary adolescent boys.
- Trial name
- NCT07193121
- Testing
- Wrestling Group, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Dental Caries
Fluoride Varnish For Childsmile Nursery School Attenders
The study will compare the effectiveness of Duraphat® fluoride varnish in preventing any further dental decay among 3-4 year old children in nursery schools.
- Trial name
- PT@3 (NCT01674933)
- Testing
- Duraphat® Fluoride Varnish, treatment as usual
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,610 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Opioid Use Disorder
Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD
Despite rising rates of fatal opioid overdoses in the United States, adolescents with OUD are far less likely than adults to receive and be retained on medication for opioid use disorder (MOUD).
- Trial name
- YORS (NCT06774248)
- Testing
- Youth Opioid Recovery Support (YORS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Potomac Health Foundations
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
AI-Supported Therapy for Depression and Anxiety Compared With Standard CBT
This study is a pivotal, randomised, controlled, non-inferiority trial evaluating "Nook," an AI-delivered, neurosymbolic, clinician-supervised digital psychological intervention for depression and anxiety, compared with standard…
- Trial name
- NCT07620340
- Testing
- AI-Digital CBT, Cognitive Behavioural Therapy
- Volunteers
- 400 people
- Sponsor
- PsyScale
Anorexia Nervosa
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
The goal of this clinical trial is to learn if psilocybin, given with psychological support, is safe and helps treat anorexia nervosa in young adults.
- Trial name
- psiAN (NCT07169747)
- Testing
- Psilocybin
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
Suicide
Alliance With Therapeutic Entourage in Support of Young Suicidal
Regardless of age, the quality of hospital care, the confidence that the young can have in the health care team, joining parents are pivotal elements and influence followed.
- Trial name
- IPSI2 (NCT02524535)
- Testing
- Therapeutic alliance
- Where
- France
- Volunteers
- 292 people
- Sponsor
- University Hospital, Caen
Workplace Culture, Help-Seeking Behavior
Evaluating a Physician Opinion Leader Intervention to Increase Utilization of Coaching/Therapy During Residency
Investigators will assess the efficacy of a physician popular opinion leader-led intervention to increase awareness and utilization of existing evidence-based coaching or therapy among post-graduate clinical trainees at Stanford.
- Conditions
- Workplace Culture, Help-Seeking Behavior, Social Stigma, Education, Medical, Continuing
- Trial name
- POL (NCT05499468)
- Testing
- Popular-Opinion Leader-led encouragement during training meetings and informal conversation
- Where
- United States
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- Stanford University
Penicillin Allergy, In-hospital Process Optimization
A Digital Stewardship Strategy for Patients With Reported Penicillin Allergy
The goal of this clinical study is to evaluate whether a digital decision support tool integrated into the electronic medical record improves antibiotic prescribing in hospitalized patients with a reported allergy to penicillin.
- Trial name
- Digitalpen (NCT07604597)
- Where
- Spain
- Volunteers
- 182 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Diabetes Mellitus, Artificial Intelligence (AI)
Artificial Intelligence-Supported Mobile Application For Diabetes Self-Management
Patients in the AI-supported mobile application group will be able to log in with a username and password that will be defined specifically for them.
- Conditions
- Diabetes Mellitus, Artificial Intelligence (AI), Self-management
- Trial name
- NCT06650098
- Testing
- artificial intelligence-supported mobile application, WEB based application
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Uludag University
Anemia, Leukemia
Epoetin Alfa or Epoetin Beta With or Without Iron Infusion in Treating Anemia in Patients With Cancer
RATIONALE: Epoetin alfa and epoetin beta may cause the body to make more red blood cells. Red blood cells contain iron that is needed to carry oxygen to the tissues.
- Conditions
- Anemia, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00482716
- Testing
- epoetin alfa, epoetin beta, iron dextran complex
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- St. Bartholomew's Hospital
Telemedicine, Pediatrics
Improving Nighttime Access to Care and Treatment; Part 4-Haiti
Children in resource-limited settings who develop illness at night are often isolated from care, resulting in progression to an emergency.
- Trial name
- INACT4-H (NCT05480930)
- Testing
- paper-based clinical decision support (dCDS) tool, digital clinical decision support (dCDS) tool
- Where
- Haiti
- Volunteers
- 7,124 people
- Sponsor
- University of Florida
Multiple Chronic Conditions
Digitally Supported Person-centered Care Systems
The case history of patients with complex and long-term needs is often stored in fragments across many different care providers, each with a separate electronic health record.
- Trial name
- DignityCare (NCT07142616)
- Testing
- 03 - Summaries of and clinical notes from several providers, 01 - Clinical notes from one provider, 02 - Access to notes from primary and secondary care
- Where
- Norway
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Parent-Child Relations, Parenting
Examine the Feasibility and Acceptability of Project Support
In this study, the investigators will conduct a proof-of-concept pilot trial of delivering the Project Support Positive Parenting Module (Project Support) to n = 30 families waiting for trauma-focused services.
- Conditions
- Parent-Child Relations, Parenting, Child Mental Disorder
- Trial name
- NCT06391229
- Testing
- Project Support
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medical University of South Carolina
Unspecified Childhood Solid Tumor, Protocol Specific
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00003194
- Testing
- filgrastim, carboplatin, cyclophosphamide
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Seattle Children's Hospital
Hemorrhage, Coagulopathy
Implementing Treatment Algorithms for the Correction of Trauma Induced Coagulopathy
This trial compares the haemostatic effect of viscoelastic haemostatic assay (VHA)-guided transfusion strategy versus non-VHA guided transfusion strategy in haemorrhaging trauma patients.
- Conditions
- Hemorrhage, Coagulopathy, Trauma
- Trial name
- iTACTIC (NCT02593877)
- Testing
- VHA algorithm
- Where
- 7 sites in Denmark, Germany and 3 more
- Volunteers
- 412 people
- Sponsor
- Queen Mary University of London