Clinical trials: Surgery- Complications
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Nonfunctional Kidney, Renal Cancer
Single-layer Robot-assisted Transperitoneal Retroperitoneal Tubeless Radical Nephrectomy
To investigate the effect of single-layer robot-assisted retroperitoneal approach for radical nephrectomy without tubularization
- Trial name
- NCT06565598
- Testing
- Single-layer robot-assisted transperitoneal retroperitoneal tubeless radical nephrectomy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The First People's Hospital of Xiushui
Morbidly Adherent Placenta
Morbidly Adherent Placenta, Diagnosis and Proper Management
The main idea of this study is to establish the diagnostic criteria for cases of morbidly adherent placenta (MAP) using different ultrasonographic modalities and compare this with intra-operative findings and postoperative…
- Trial name
- NCT05307016
- Testing
- Two dimensional ultrasonography power and color doppler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Colorectal Cancer
Does Administration of Antibiotics in Patients Undergoing Surgery for Colorectal Cancer Result in Less Complications and Better Prognosis?
The primary objectives of this randomized clinical trial are to evaluate if perioperative SDD can reduce clinical anastomotic leakage rate and its septic consequences as well as other infectious complications.
- Trial name
- SELECT (NCT01740947)
- Testing
- Selective decontamination of the digestive tract (SDD) (colistin sulfate, tobramycin, amphotericin B)
- Where
- 5 sites in Netherlands
- Volunteers
- 485 people
- Sponsor
- H. Jaap Bonjer, PhD
Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery
Near Infrared Spectroscopy for the Detection of Acute Kidney Injury in Children Following Cardiac Surgery
One in a hundred children is born with a heart defect. Some children require heart surgery within the first few days of life, while others can wait until they are older.
- Conditions
- Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery, Children
- Trial name
- NCT01382758
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postoperative Nausea and Vomiting (PONV)
Dexamethasone for Prevention of Postoperative Vomiting After Laparoscopic Gynecologic Surgery
Postoperative nausea and vomiting (PONV) are common and distressing complications following laparoscopic gynecologic surgery. This randomized controlled trial evaluated whether a single preoperative intravenous dose of…
- Trial name
- PONV-DEX-GYN (NCT07421817)
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Rawalpindi Medical College
Enhanced Recovery After Surgery, Hospital Stay, Length of Stay in Hospital From Time of Surgery Till Discharge
Resumption of Enteral Feeding After Bowel Anastomosis
Resumption of oral feeding after small intestine surgery is a matter of controversy .Some surgeons advocate early resumption while others don't.early feeding is initiated as soon as the patient recovers from effects of…
- Conditions
- Enhanced Recovery After Surgery, Hospital Stay, Length of Stay in Hospital From Time of Surgery Till Discharge, Defecation, Vomiting, Postoperative
- Trial name
- NCT06906289
- Testing
- resumption of enteral feeding within 24 hours of surgery, resumption of enteral feeding after 24-48 hours
- Where
- Pakistan
- Volunteers
- 204 people
- Sponsor
- Khyber Teaching Hospital
Postoperative Pain, Spinal Fusion
Postoperative Pain Control Using Local Wound Infiltration in Adolescent Idiopathic Surgery
Non-opioid methods of pain management following posterior spinal fusion (PSF) have become increasingly popular given the rise of opioid abuse and opioid-related deaths.
- Trial name
- NCT04730531
- Testing
- Local infiltration with 0.25% bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Pain, Postoperative
Epidemiology Study and Risk Factor Analysis on Chronic Post-surgical Pain After Video-assisted Thoracic Surgery
This study is a nationwide multi-center study to investigate the incidence and risk factors of chronic post-surgical pain (CPSP) after receiving video-assisted thoracic surgery (VATS).
- Trial name
- NCT05473728
- Where
- China
- Volunteers
- 886 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Nephroblastoma With Vena Cava Thrombosis
Vascular Thrombus Involvement in Nephroblastoma
Nephroblastoma (Wilms tumor) is the most common kidney tumor in children. It is a malignant embryonic tumor with a good prognosis with more than 85% long-term survival with appropriate chemotherapy, surgery (which most often…
- Trial name
- VIN (NCT05195411)
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Complications, Cardiovascular Diseases
Comparing Traditional Risk Scores and an AI-Based Multimodal Model for Predicting Cardiovascular Events After Gastrointestinal Surgery
The goal of this observational study is to develop and evaluate an artificial intelligence (AI)-based multimodal model for predicting major cardiovascular events within 30 days after gastrointestinal surgery in adults at Bach Mai…
- Conditions
- Postoperative Complications, Cardiovascular Diseases, Digestive System Surgical Procedures
- Trial name
- GI-MACE-AI (NCT07539532)
- Where
- Vietnam
- Volunteers
- 5,000 people
- Sponsor
- Bach Mai Hospital
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Pain, Postoperative, Dental Pain
A Study of Acetaminophen for Post Surgical Dental Pain
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to…
- Trial name
- NCT04018612
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Hypotension, Hip Fractures
Heart and Renal Failure in Hip Fracture Surgery
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension.
- Conditions
- Hypotension, Hip Fractures, Renal Insufficiency, Heart Injuries
- Trial name
- NCT03532919
- Testing
- Serum Tropinin
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Sahlgrenska University Hospital
Emergence Agitation, Pain
Risk Factors for Pediatric Emergence Agitation and Analysis of Serum or Urine Metabonomics in Children With Agitation
It is known that some factors are associated with emergence agitation(EA), and investigators are still unable to predict accurately those who undergoing maxillofacial surgery are at great risks.This study intend to identify the…
- Conditions
- Emergence Agitation, Pain, Metabolomics
- Trial name
- NCT04807998
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Laparoscopic Surgery, Pediatrics
Effect of Palonosetron, Ondansetron and Dexamethasone in the Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is an important outcome for the patient; patients generally rate PONV as worse than postoperative pain.
- Conditions
- Laparoscopic Surgery, Pediatrics, Nausea and Vomiting, Postoperative, Antiemetics
- Trial name
- NCT05439798
- Testing
- Ondansetron+Dexamethasone, Palonosetron+Dexamethasone, Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Selcuk University
Vaginal Fistula
Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
This facility-based, multi-center randomized controlled trial (RCT) will test the non-inferiority of short-term (7 day) urethral catheterization compared to longer-term (14 day) urethral catheterization in terms of predicting…
- Trial name
- NCT01428830
- Testing
- 7-day catheterization following fistula repair surgery, 14 day catheterization
- Where
- 8 sites in Democratic Republic of the Congo, Ethiopia and 6 more
- Volunteers
- 524 people
- Sponsor
- EngenderHealth
Liver Transplantation
Application of in Vivo Splitting Technique in Adult Liver Transplantation
The feasibility of split liver transplantation (SLT) remains controversial. This study aimed to evaluate the outcomes of SLT in adult recipients and to identify specific areas of improvements.
- Trial name
- NCT06925828
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Postoperative Pain
Effect of Oral Melatonin on Postoperative Analgesia After Thoracotomy in Infants
Thoracotomy pain is one of the severest pain that should be taken seriously, especially in children. (1) Inadequate postoperative pain management can compromise respiratory function, delay postoperative extubation, increase the…
- Trial name
- NCT05141344
- Testing
- Melatonin 3 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
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