Clinical trials: Surgery-first
Healing Wound
Autologous Epidermal Cell Treat for Nonhealing Postoperative Wound
Postoperative incision healing (Postoperative incision non - ranging) occurred in the surgical incision more than 2 weeks after the operation is still not healing wounds.
- Trial name
- NCT06173908
- Testing
- cell treatment, control treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Thyroid Gland Disease, Surgery
TOETVA Feasibility and Complications - Single Center First Experience
All participants who underwent (or will undergo) a transoral endoscopic thyroidectomy via vestibular approach (TOETVA) at the investigators' center are observed for complications and feasibility of this surgery.
- Trial name
- NCT05396703
- Testing
- TOETVA
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Microtia
Long-Term Follow-Up Study of Unilateral Microtia Patients Implanted With AUR-201
Long-term follow-up of unilateral microtia patients implanted with AUR-201.
- Trial name
- AUR-201 (NCT06078566)
- Testing
- AUR-201
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Auregen Biotherapeutics, SA
Pancreatic Cancer
Gemcitabine With or Without Combination Chemotherapy and Radiation Therapy in Treating Patients With Nonmetastatic Pancreatic Cancer That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, fluorouracil, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00416507
- Testing
- fluorouracil, gemcitabine hydrochloride, liposomal cisplatin
- Volunteers
- 190 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Surgery
Immersive Care - Virtual Reality(VR) 360 Pediatric Surgery Preparation.
Context: This study is part of the larger Immersive Care project which (in short) seeks the connection between technology and care by conducting feasibility studies with promising technological interventions tailored to care.
- Trial name
- NCT04658030
- Testing
- VR 360 video surgery preparation, Care as usual
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Thomas More University of Applied Sciences
Osteosarcoma Metastatic, Pulmonary Disease
Osteosarcoma With Resectable Pulmonary Metastasis: A Retrospective Study
According to EURAMOS-1, 17% of osteosarcoma patients were considered to have metastases at diagnosis. In this selected cohort, the reported 5-year EFS from diagnosis of 28% compares well to previous results reported from…
- Conditions
- Osteosarcoma Metastatic, Pulmonary Disease, Resectable Sarcoma, Survival
- Trial name
- NCT04546243
- Testing
- resection group, radiotherapy group
- Where
- 2 sites in China
- Volunteers
- 127 people
- Sponsor
- Peking University People's Hospital
Congenital Heart Disease
Platelets or Fibrinogen as First-line Treatment for Bleeding During Pedatric Heart Surgery
The study aims to test whether platelet transfusion or fibrinogen concentrate is the most effective treatment of intraoperative bleeding, when performing open heart surgery with cardiopulmonary bypass on children with congenital…
- Trial name
- NCT04807621
- Testing
- Platelet transfusion, Fibrinogen concentrate
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Sahlgrenska University Hospital
Surgery, Anesthesia, Endotracheal
The Videolaryngoscopy in Small Infants
Complications related to infant (≤ 1 year) airway management are under-appreciated because of few rigorous and targeted studies.
- Trial name
- VISI (NCT03396432)
- Testing
- Video Laryngoscopy for ET placement, Direct Laryngoscopy for ET Placement
- Where
- 5 sites in United States, Australia
- Volunteers
- 566 people
- Sponsor
- Children's Hospital of Philadelphia
Abortion in First Trimester, Pain, Procedural
Ketamine Versus Fentanyl for Surgical Abortions
Ketamine is commonly used for procedural sedation and analgesia. It is widely used for trauma cases in the emergency department and is considered a superior agent in the outpatient setting due to its lack of respiratory and…
- Conditions
- Abortion in First Trimester, Pain, Procedural, Opioid Use
- Trial name
- NCT04871425
- Testing
- Ketamine, Fentanyl
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hepatocellular Carcinoma
Laparoscopic Surgery Versus Radiofrequency Ablation for Recurrent HCC
Hepatocellular carcinoma (HCC) is the fifth most common and the third leading cause of death from cancer worldwide1 . Hepatectomy is still the main effective treatment for HCC accompanying with well-preserved cirrhosis when liver…
- Trial name
- NCT02535117
- Testing
- Laparoscopic Surgery(LS), RFA
- Volunteers
- 216 people
- Sponsor
- Sun Yat-sen University
Dentofacial Deformities
Splintless Virtual Surgical Plan with Mandible-first Technique: 3D Accuracy Analysis
Accuracy assessment through three-dimensional superposition of the post-operative volumetric CT and the digital therapeutic project files.
- Trial name
- MandiFirst (NCT06907745)
- Testing
- Bimaxillary Osteotomy
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Osteoarthritis, Hip Dislocation
Supine Sleeping After Total Hip Replacement
Aim of the current study is to test the non-inferiority hypothesis of differences in early hip dislocation between a group of patients who will be restricted to sleep in supine position and a group without restricted sleeping…
- Trial name
- NCT02107248
- Testing
- Sleep position: no restrictions, Sleep position: supine
- Where
- Netherlands
- Volunteers
- 456 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Anxiety, Pain
Effectiveness of Virtual Reality in Reducing Anxiety and Pain During the First Postoperative Orthopedic Dressing Change in Pediatric Patients
The goal of this randomized clinical trial is to learn whether immersive virtual reality can reduce anxiety and pain in children and adolescents undergoing postoperative orthopedic dressing changes.
- Conditions
- Anxiety, Pain, Post Operative
- Trial name
- VR OrthoPed (NCT07729020)
- Testing
- Immersive Virtual Reality Distraction, Standard Postoperative Dressing Care
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Gianluca Catania
Lymphadenopathy, Stage I Testicular Seminoma
Retroperitoneal Lymph Node Dissection in Treating Patients With Testicular Seminoma
This phase II trial studies how well retroperitoneal lymph node dissection (RPLND) works in treating patients with stage I-IIa testicular seminoma.
- Conditions
- Lymphadenopathy, Stage I Testicular Seminoma, Stage II Testicular Seminoma
- Trial name
- NCT02537548
- Testing
- Laboratory Biomarker Analysis, Retroperitoneal Lymph Node Dissection
- Where
- 14 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Southern California
MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye
A Comparison of Patient Perceptions Undergoing Manual Cataract Surgery (MCS) vs Refractive Laser-assisted Cataract Surgery (ReLACS) in First and Second Eyes
The focus of this study is to assess how pain can be mitigated for patients undergoing cataract surgery through the early application of anesthesia prior to the surgery as compared to the standard timing, and by using the ReLACS…
- Conditions
- MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye, Early Anesthesia vs Standard Anesthesia
- Trial name
- NCT04623229
- Testing
- MCS, ReLACS Early, ReLACS Standard
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Malocclusion, Angle Class III
Evaluation of Surgical Outcomes of Patients Treated With the Surgery First Approach and Aligners
The purpose of this prospective study is to compare treatment outcomes and the quality of life of skeletal Class III patients treated with conventional fixed appliances and aligners undergoing Surgery-first approach.
- Trial name
- NCT05822271
- Testing
- Orthognathic Surgery
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Surgically Repaired Unilateral Cleft Lip and Palate
Evaluation of Arch Dimensions of Children With Surgically Repaired Unilateral Cleft Lip and Palate
The aim of the study is to assess arch dimensions among children with surgically repaired unilateral cleft lip and palate.
- Trial name
- NCT03219021
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Menna Allah Mohammed Awad
Minimally Invasive Surgery Basic Skills
Goal-directed MIS Simulation Training With the LTB-Curriculum Prior to First Operations on Patients: Study Protocol for a Multi-centre Randomized Controlled Validation Trial (NOVICE)
Background: Laparoscopic surgical procedures have become increasingly established in operative medicine. They require special motor, haptic, and spatial-visual skills to perform the interventions safely and effectively.
- Trial name
- NOVICE (NCT03040544)
- Testing
- LTB-Curriculum, Laparoscopic cholecystectomy
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
CHD - Congenital Heart Disease
Feasibility of Home Telemonitoring of Infants With Congenital Heart Disease Awaiting Surgery During the First Year of Life
Actually, there is no telemonitoring program that includes newborns or infants with congenital heart disease awaiting cardiac intervention.
- Trial name
- Blue-Line (NCT06998290)
- Testing
- Blue-Line home telemonitoring program
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Hallux Rigidus, Orthopedic Disorder
Risk for Reoperation After First MTP Joint Arthrodesis
We will screen all first metatarsophalangeal joint arthrodeses performed between 2010 and 2022 in Helsinki University Hospital. Information about demographics and additional diagnoses will be yielded from data pool of medical…
- Conditions
- Hallux Rigidus, Orthopedic Disorder, Surgery, Complication of Surgical Procedure
- Trial name
- NCT05795127
- Testing
- First metatarsophalangeal joint arthrodesis
- Where
- Finland
- Volunteers
- 1,213 people
- Sponsor
- Hospital District of Helsinki and Uusimaa