Clinical trials: Surgical Bleeding
Bleeding, Site Infection
Outcome of Plastibell Circumcision Versus Open Method Circumcision
To compare the outcomes of plastibell circumcision method with open surgical technique in infants presenting at tertiary care hospital.
- Trial name
- NCT06366984
- Testing
- plastibell, open method
- Where
- Pakistan
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Infection
Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery
There was no evidence to judge the effects of preventative antibiotics for extractions of severely decayed teeth, teeth in diseased gums, or extractions in patients who are sick or have low immunity to infection.
- Trial name
- NCT03844776
- Testing
- Co-Amoxiclav, Paracetamol, Chlorhexidine mouthwash
- Where
- Saudi Arabia
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Taibah University
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Post-Op Complication
A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery
The purpose and objectives of this study is to investigate whether reducing the existing arm restrictions on patients who receive Cardiac Implantable Electronic Devices (CIED) will result in an improved patient experience post…
- Trial name
- LENIENT (NCT04915261)
- Testing
- Lenient Arm Restriction, Strict Arm Restriction
- Where
- Canada
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Hypotension During Surgery, Blood Loss, Surgical
Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered.
- Trial name
- NCT05474027
- Testing
- Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Epistaxis
Nasal Intubation Using a Parker Flex-tip Endotracheal Tube Compared to a Nasal RAE Tube
The purpose of this study is to determine the degree of epistaxis following nasal intubation with either a nasal endotracheal (RAE) tube with bevel facing left or Parker Flex-Tip endotracheal tube with bevel facing posteriorly…
- Trial name
- NCT02315677
- Testing
- Nasal Intubation with nasal RAE endotracheal tube, Nasal Intubation with Parker Flex-Tip endotracheal tube
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Surgical Blood Loss, Surgical Hemorrhage
TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss
The research team proposes a prospective, observational study to better understand how TEG can be useful in guiding clinical practice in the Main OR for subject's undergoing high transfusion risk surgeries.
- Conditions
- Surgical Blood Loss, Surgical Hemorrhage, Post Operative Hemorrhage
- Trial name
- NCT05379530
- Testing
- Thromboelastography (TEG), Anesthesia Provider Survey
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Placenta Previa
Balloon Tamponade Vs B-Lynch In Placenta Previa
Patients were allocated to group A and B. In group A, balloon tamponade (using Foley catheter 28 Fr) was used intra-operatively to prevent post-partum hemorrhage.
- Trial name
- NCT05133167
- Testing
- Balloon Tamponade or B-Lynch
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CMH Jhelum
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Morbid Obesity, Pulmonary Embolism
Laparoscopic Bariatric Surgery: Two Regimens of Venous Thromboprophylaxis: Prospective Randomized Study
Obese patients undergoing bariatric surgery warrant VTE prophylaxis because they are at high risk for developing a fatal pulmonary embolism or postthrombotic syndrome.
- Trial name
- NCT02128178
- Testing
- Enoxaparin 40 mg 2 hours before arm, Enoxaparin 40 mg 12 hours before arm
- Where
- Egypt
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Controlling Mild to Moderate Bleeding During Surgery
The EVARREST® Pediatric Mild or Moderate Liver and Soft Tissue Bleeding Study
The objective of this study is to evaluate the safety and hemostatic effectiveness of EVARREST as an adjunct to controlling mild to moderate soft hepatic parenchyma or soft tissue bleeding during open hepatic, abdominal, pelvic…
- Trial name
- NCT03255174
- Testing
- EVARREST® Fibrin Sealant Patch
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Blood Loss, Surgical
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
The uterine fibroids are the most common benign tumors found in the female reproductive system. Uterine fibroids commonly cause heavy menstrual periods.
- Trial name
- NCT07721623
- Testing
- Carbetocin
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Alex Ekwueme Federal University Teaching Hospital
Clotting and Bleeding Disorders, Child Development
Determination of ClotPro Paediatric Reference Range Study
A new thromboelastometry analyser (ClotPro, Enicor GmbH, Munich, Germany) with improved technology was developed. This device has an improved new-generation viscoelastometric testing technique and enables the detection and…
- Conditions
- Clotting and Bleeding Disorders, Child Development, Infant Development, Coagulopathy
- Trial name
- NCT04190615
- Testing
- thromboelastometry test (TEM test)
- Where
- Slovakia
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- National Institute of Children's Diseases, Slovakia
Hypothermia; Anesthesia
Body Temperature and Perioperative Bleeding in Adolescent Idiopathic Scoliosis Surgery
In this study, patient groups in which normothermia is preserved by using multiple active warming methods in the intraoperative period in AIS surgery, followed by a single compressed air blowing system and allowed mild to…
- Trial name
- NCT04686214
- Testing
- heating
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL
This study aims to analyze the efficacy of intravenous tranexamic acid (TXA) in patients undergoing total hip arthroplasty (THA).
- Conditions
- Blood Loss, Surgical, Tranexamic Acid Adverse Reaction, Hip Replacement
- Trial name
- NCT03019198
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Brazil
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Tranexamic Acid, Orthognathic Surgery
The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery
This study seeks to answer the question: Does a single pre-operative dose of tranexamic acid have a statistically significant reduction in blood loss during orthognathic surgery? If it does, this drug may begin to be used…
- Trial name
- TXA-OMFS (NCT03433144)
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nick Emanuele
Adolescent Idiopathic Scoliosis
Does Tranexamic Acid Decrease Blood Loss in Pediatric Idiopathic Scoliosis Surgery?
Adolescent idiopathic scoliosis surgery is an extensive procedure associated with significant blood loss frequently requiring the transfusion of blood.
- Trial name
- NCT01813058
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Nails, Ingrown, Coagulation Defect; Bleeding
Hemostasis Assesment After Application of Lyophilisate Collagen in Nail Surgery
The objective of this study is to evaluate the hemostatic capacity of two types of collagen hemostatic sponges in nail surgery. It is a randomized triple-blind clinical trial with two experimental groups (medium porosity collagen…
- Trial name
- NCT05140161
- Testing
- collagen
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Seville
Cardiac Surgery, Bone Wax, NU-KNIT, Median Sternotomy, Deep Sternal Wound Infection, Surgical Site Infection
Surgicel NU-KNIT Vs Bone Wax on Median Sternotomy
Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
- Trial name
- NBCS (NCT06869772)
- Testing
- Closure of sternotomy
- Where
- Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Hysterectomy (MeSH nr: E04.950.300.399)
Transforming Global Surgery Capacity and Capability Through Affordable Virtual Reality
The goal of this randomized controlled trial was to evaluate whether Deliberate Virtual Reality (VR) training can improve surgical skills, knowledge, and confidence in performing postpartum hysterectomy among junior-level Zambian…
- Trial name
- NCT07403526
- Testing
- Deliberate Virtual Reality (VR) Training, Standard Clinical Training
- Where
- Zambia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University