Clinical trials: Surgical Procedure, Operative
Intrabony Periodontal Defects
Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
- Trial name
- NCT07722390
- Testing
- Injectable PRF, MINST
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nails, Ingrown
Nonrandomized Assessment of Ingrown ToenaiLs Treated by Excision of Skinfold Rather Than Toenail
Ingrown toenails occur when the nail grows into the surrounding skin, resulting in pain and infection. The most common procedure to treat this problem is a wedge excision (removal of part of the toenail) and matricectomy…
- Trial name
- NAILTEST (NCT02067897)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Michael Livingston
Hypoxemia, Ventilator Lung
Driving Pressure-guided Lung Protective Ventilation
The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving…
- Trial name
- DPV (NCT06361420)
- Testing
- Driving pressure-guided positive end expiratory pressure, Optimal oxygenation-guided positive end expiratory pressure, Ventilation strategy
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Yong Lin, PhD
Infections
Role of Oxidized Regenerated Cellulose (ORC) Applied to "Dirty" Surgical Wounds
The purpose of this study is to determine whether oxidized regenerated cellulose (ORC) is effective to reduce the risk of surgical site infections (SSI).
- Trial name
- ORC (NCT00947089)
- Testing
- oxidized regenerated cellulose (Fibrillar SURGICEL), iodoform gauze
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- Catholic University of the Sacred Heart
Periodontal Diseases, Peri-implantitis
Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment
Peri-implantitis is a infectious disease that resides in the mucosa surrounding dental implants and also affects the supporting bone.
- Trial name
- NCT01852253
- Testing
- 2% chlorhexidine, 0.12% chlorhexidine
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- University Medical Center Groningen
Osteoarthritis, Hallux Rigidus
Artelon Metatarsophalangeal (MTP) Spacer
The aim of this prospective, case series is to evaluate the surgical treatment of painful and disabling osteoarthrosis in the MTP-I joint by insertion of an Artelon MTP Spacer.
- Trial name
- NCT01028469
- Testing
- Artelon MTP Spacer
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Artimplant AB
Tonsillectomy, Adenotonsillectomy
Celecoxib for Pediatric Adenotonsillectomy
The investigators' study will involve the administration of either placebo or celecoxib to children aged 2 to 18 years of age undergoing tonsillectomy and assessing pain relief, impact on quality of life and side effect profile.
- Conditions
- Tonsillectomy, Adenotonsillectomy, Pain, Postoperative
- Trial name
- NCT00849966
- Testing
- Celebrex suspension
- Where
- Canada
- Volunteers
- 282 people
- Sponsor
- Children's Hospital of Eastern Ontario
Hirschsprung Disease
Minimally Invasive Surgical Intervention for Hirschsprung's Disease in Pediatric Patients
Hirschsprung's disease (HD) is a congenital disorder characterized by the absence of enteric ganglion cells in the distal bowel, leading to functional obstruction, delayed meconium passage in neonates, and chronic defecation…
- Trial name
- NCT06874686
- Testing
- Minimally invasive laparoscopic pull-through surgery
- Where
- Vietnam
- Volunteers
- 1,050 people
- Sponsor
- National Children's Hospital, Vietnam
Maxillofacial Abnormalities
Mandibular Stability and Dentofacial Deformity
The present study intends to clarify whether there is positional mandibular stability in patients to be submitted to orthognathic surgery.
- Trial name
- NCT01486069
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anxiety, Fear
Smartphone-Based Cartoon Distraction During Cast Removal in Children
Cast removal can cause considerable fear and anxiety in children despite being a generally painless procedure. This randomized controlled trial evaluated whether watching a cartoon on a smartphone during circumferential…
- Trial name
- CAST-REMOVE (NCT07842627)
- Testing
- Smartphone-Based Cartoon Distraction, Standard Cast Removal Care
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Caner Oguk
Tonsillectomy, Hemorrhage
HemORL: Monocentric, Prospective, Comparative Study on the Use of a Haemostatic Vacuum Device During Tonsillectomy in Children
The long-term objective of this study is to prove: the equivalence of the number of post-operation hemorrhages, and maybe a decrease of the number of secondary hemorrhages the decrease of pain and quicker re-feeding an easier…
- Conditions
- Tonsillectomy, Hemorrhage, Postoperative Complications
- Trial name
- HemORL (NCT01904461)
- Testing
- Vacuum device, Conventional surgery
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
Aorto Iliac Occlusive Disease
Laparoscopic Surgical Treatment of Aorto-iliac Occlusive Disease
Patients with aorto-iliac occlusive disease (TASC, type D) operated with a totally laparoscopic aortobifemoral bypass operation and open aortobifemoral bypass operation will be followed up and the results will be compared between…
- Trial name
- LAS (NCT01259908)
- Testing
- Laparoscopic vs open Ygraft
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Infertility
Fresh Vs Frozen Surgical Sperm in IVF
The primary objective of this study is to determine if the use of frozen surgical testicular sperm specimens for ICSI lead to different IVF outcomes when compared with the use of fresh surgical testicular sperm for ICSI.
- Trial name
- NCT03361982
- Testing
- Slow Freezing and Thawing
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Cleft Palate Lip
Cleft Palate Surgical Simulator: Improvement in Surgical Trainees' Knowledge and Confidence.
Trainees' experience in cleft surgery is limited due to the high-risk nature of the surgery and centralization of cleft care. Simulations allow trainees to learn complex surgical skills whilst ensuring patient safety.
- Trial name
- NCT04489680
- Testing
- Educational
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Osteoarthritis
Comparison of Ways to Prepare Patients for Decisions About Joint Replacement Surgery
Ministries of Health consider wait lists for total joint replacement a top priority. Research priorities to manage wait lists indicate the need to establish benchmarks that consider patient preferences.
- Trial name
- NCT00911638
- Testing
- Patient decision aid, Usual care
- Where
- 2 sites in Canada
- Volunteers
- 343 people
- Sponsor
- Ottawa Hospital Research Institute
Appendicitis, Perforated Appendicitis
Comparative Study Between Laparoscopic and Open Appendectomy of Complicated Appendicitis
Acute appendicitis is one of the most common surgical emergencies in children. In complicated cases, where the appendix has perforated, become gangrenous, or caused peritonitis and purulent contamination, determining the optimal…
- Conditions
- Appendicitis, Perforated Appendicitis, Gangrenous Appendicitis, Peritonitis
- Trial name
- NCT07879235
- Testing
- Laparoscopic Appendectomy, Open Appendectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Pancreatitis
Late Phase Acute Pancreatitis: a Tailored Step-up Approach
Several interventional and surgical procedures are available to treat moderate-to-critical acute pancreatitis (AP) in its late phase.
- Trial name
- TSA (NCT04870268)
- Testing
- percutaneous drainage, endoscopic approach, surgical internal derivation of WON
- Volunteers
- 47 people
- Sponsor
- University of Pisa
Congenital Afibrinogenemia, Hypofibrinogenemia
FIB Grifols Congenital Deficiency for On-demand Treatment and Surgical Prophylaxis
This is a phase 3, multi-center, prospective, open-label, single-arm, clinical trial to be carried out in subjects with congenital fibrinogen deficiency manifested as afibrinogenemia or severe hypofibrinogenemia.
- Trial name
- NCT04636268
- Testing
- FIB Grifols
- Sponsor
- Instituto Grifols, S.A.
Chronic Calculous Cholecystitis
Extent of Surgical Trauma in Open and Laparoscopic Cholecystectomy
The aim of this work is to evaluate which of the two types of operation (traditional/open and laparoscopic) has more impact on patients who were operated electively due to their chronic calculous cholecystitis.
- Trial name
- ESTOLC (NCT01077115)
- Testing
- Laparoscopic cholecystectomy, Open Surgery
- Where
- Montenegro
- Volunteers
- 120 people
- Sponsor
- Ministry of Health, Montenegro
Colorectal Surgical Procedures
A Study of the ECHELON Contour Curved Cutter Stapler Device in Colorectal Procedures
The purpose of this study is to prospectively generate device-specific clinical data related to the performance of Echelon Contour per its instructions for use (IFU).
- Trial name
- NCT05133141
- Testing
- Echelon Contour
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Ethicon Endo-Surgery
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