Clinical trials: Surgical Procedures, Operative
Osteomyelitis, Infections
Surgical Treatment of Osteoarticular Infections Using Bioactive Bone Substitute
This prospective research project aims to evaluate the effectiveness and clinical outcomes of utilizing antibiotic-impregnated bioactive bone substitute (PerOssal®) in the surgical management of osteoarticular infections.
- Conditions
- Osteomyelitis, Infections, Fracture, Antibiotics
- Trial name
- NCT06402292
- Testing
- OSTEOMYELITIS SURGICAL TREATMENT WITH LOCAL ANTIBIOTICS AND PEROSSAL
- Volunteers
- 25 people
- Sponsor
- Federal University of São Paulo
Social Deprivation
Social Deprivation and Postoperative Mortality
Socioeconomic factors are associated with differences in health outcomes, but their impact on surgical patients is still not well understood, especially in low- and middle-income countries.
- Trial name
- NCT07621211
- Where
- 7 sites in Brazil
- Volunteers
- 45,000 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Female Genital Fistula, Incontinence
Adverse Outcomes Following Female Genital Fistula Repair
Following genital fistula repair, fistula repair breakdown and recurrence, persistent and incidence incontinence are major adverse outcomes, limiting women's health and wellbeing.
- Trial name
- Mulisa (NCT05437939)
- Where
- Uganda
- Volunteers
- 802 people
- Sponsor
- University of California, San Francisco
Progressive Scoliosis
Surgical Treatment of Progressive Scoliosis With "NEMOST" Growing Rod
The purpose of this study is to evaluate the performance of the device "NEMOST" on maintaining of the correction of the scoliosis with growth preservation and avoiding iterative surgeries.
- Trial name
- NEMOST (NCT02266667)
- Testing
- 2 NEMOST rods : bilateral vertebral-pelvic implantation, 1 NEMOST rod :unilateral vertebral-pelvic implantation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Diseases
TachoSil Paediatric Liver Trial (TC-019-IN)
The overall objective is to assess the haemostatic efficacy and safety of TachoSil for control of local bleeding in paediatric patients undergoing surgical resection of the liver with our without segmental liver transplantation.
- Trial name
- NCT00365248
- Testing
- Fibrinogen human (TachoSil)
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Nycomed
Balance Control
Impact of Physical Activities on Balance in Patient With Strabismic Amblyopia
The aim of this study is to determine the effect of physical activities on balance in patient with amblyopia after strabismus surgery.
- Trial name
- NCT06758063
- Testing
- exercises therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid
Carbon Dioxide
The Effect of Wearing Masks on End-tidal Carbon Dioxide and Pulse Oximetry
An Interventional Study is planned with the primary purpose of screening for changes in end-tidal carbon dioxide (ETCO2), inspired carbon dioxide (ICO2), and other vital signs that may develop after donning a disposable surgical…
- Trial name
- NCT05114993
- Testing
- wearing a disposable surgical mask
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Patrick Brooks
Surgical Simulation Education
Development and Evaluation of Low-Cost Non-Animal Biological Simulation Models for Undergraduate Surgical Training in Trauma Tissue Reconstruction
This study evaluated two low-cost, non-animal biological simulation models for teaching basic surgical skills to undergraduate medical students.
- Trial name
- NCT07820345
- Testing
- Suturing Simulation Training, Tendon Repair Simulation Training
- Where
- India
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Sphenopalatine Ganglion Block, General Anesthesia
Sphenopalatine Ganglion Block as Adjuvant to General Anesthesia Regarding the Quality of Surgical Field in Trans-Sphenoidal Endoscopic Hypophysectomy
This study aims to evaluate the efficacy of ultrasound guided sphenopalatine ganglion block (SPGB) through the suprazygomatic approach in optimizing the quality of surgical field as well as its effect on postoperative pain relief…
- Conditions
- Sphenopalatine Ganglion Block, General Anesthesia, Quality of Surgical Field, Trans-Sphenoidal Endoscopic Hypophysectomy
- Trial name
- NCT07569952
- Testing
- Sphenopalatine ganglion block using bupivacaine + dexamethasone, General anesthesia
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Surgical Procedure
Postponement Rate of Elective Surgical Procedures
Postponement of elective surgical procedures is a major issue in health care facilities. It increases burden on hospitals and healthcare systems as well as misery of the patients and their family members.
- Trial name
- Postponement (NCT05352984)
- Where
- Pakistan
- Volunteers
- 1,221 people
- Sponsor
- Hayatabad Medical Complex
Influenza Human
Face Masks for Preventing Influenza Transmission
This work aims to measure the effectiveness of face mask worn by a patient with flu to avoid transmission to other persons in the household.
- Trial name
- GRIPMASK (NCT00774774)
- Testing
- control, Face mask
- Where
- France
- Volunteers
- 372 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Congenital Heart Disease in Children
Left Ventricular Dysfunction Post-surgical Patent Ductus Arteriosus Ligation in Children: Predictor Factors Analysis
Background: PDA is viewed as a standout amongst the most widely recognized congenital heart defects in children and its closure is responsible for many hemodynamic changes that require intervention and care.
- Trial name
- NCT04018079
- Volunteers
- 50 people
- Sponsor
- South Valley University
Endometritis, Wound Infection
Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
The Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) study is a large pragmatic multi-center randomized clinical trial designed to evaluate the comparative effectiveness and safety of azithromycin-based extended-spectrum…
- Conditions
- Endometritis, Wound Infection, Abscess, Surgical Site Infection
- Trial name
- C/SOAP (NCT01235546)
- Testing
- Azithromycin and standard of care
- Where
- 9 sites in United States
- Volunteers
- 2,013 people
- Sponsor
- Alan Tita
Surgery
Knot Tying Surgical Simulator for Vessel Ligation
The investigators developed a bench-top knot tying simulator (KNOTI), with computer acquired assessment. Fifteen attending surgeons and 30 first year surgical residents were recruited to the study held at tertiary medical center…
- Trial name
- NCT03688997
- Testing
- Simulator training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Scoliosis, Kyphosis
The Spinal Navigation Trial - Surgical Navigation or Free Hand Technique in Spine Surgery
The spinal navigation trial (SPINAV) is a randomized controlled trial (RCT) evaluating the use of computer-assisted navigation in surgery for spinal deformity
- Trial name
- SPINAV (NCT05107310)
- Testing
- Pedicle screws insertion by free hand technique, Pedicle screws insertion using ARSN, Pedicle screws insertion using IRSN
- Where
- Sweden
- Volunteers
- 62 people
- Sponsor
- Karolinska Institutet
Surgical Site Infections, Hypothermia
Feedback on Perioperative Temperature Management and Patient Outcomes: Three-arm Trial to Compare Feedback
The investigators aim to assess the impact of benchmarked and ranked feedback on anesthesiologists' perioperative temperature management and subsequent patient outcomes.
- Trial name
- NCT02414191
- Testing
- Benchmarked Feedback, Ranked Feedback
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Idiopathic Toe-walking
Efficacy of Surgery for Idiopathic Toe Walking
BACKGROUND: For children who walk on their tip toes, surgery is often done to lengthen their Achilles Tendon. However, there is little research to help children's surgeons choose which children with idiopathic toe walking should…
- Trial name
- FOREFOOT (NCT06610591)
- Testing
- Achilles Lengthening Surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Hydrocephalus
Role of Endoscopic Third Ventriculostomy Imanagement of Hydrocephalus in Pediatric Age Group; Clinical and Surgical Outcome
Endoscopic third ventriculostomy in cases of hydrocephalus provide less invasive and safe technique than ventriculoperitoneal Shunt also decrease complications of ventriculoperitoneal Shunt
- Trial name
- NCT07694518
- Testing
- Fenestration of the floor of the third ventricle, Endoscopic third ventriculostomy of the brain third ventricle, Endoscopic third ventriculostomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
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