Clinical trials: Surgical Procedures, Operative
Hyperoxia
Hyperoxygenation in Anesthetized Children
This study is aiming at assessing the effect of inspired oxygen fraction during general anesthesia on children's lung mechanics and volume.
- Trial name
- OXPED (NCT02384616)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Walid HABRE
Neuromuscular Blockade
Depth of Neuromuscular Blockade and the Perioperative Conditions in Laparoscopic Surgery in Pediatric Population
This randomized study prospectively evaluates our experience with administration of cisatracurium and rocuronium antagonized by sugammadex and evaluates the effects of various depths of neuromuscular blockage on providing optimal…
- Trial name
- PedLapBlock (NCT02546843)
- Testing
- Rocuronium, Cisatracurium, Nonspecific Neuromuscular Blockade reversal
- Where
- Czechia
- Volunteers
- 66 people
- Sponsor
- Brno University Hospital
Wrist Fracture, Distal Radius Fracture
Defining Displacement Thresholds for Surgical Intervention for Distal Radius Fractures - a Delphi Study
Wrist (distal radius fractures) are very common injuries. Despite this there is still much controversy about the best way to treat them and in particular which ones require intervention.
- Trial name
- NCT03126474
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Gynecologic Laparoscopic Surgery, Minimally Invasive Surgical Procedures
Impact of a Preoperative Instructional Video on Patient Preparedness
In this study, the investigators will evaluate the impact of a pre-operative instructional video for patients undergoing minimally invasive gynecologic surgery.
- Trial name
- NCT07364968
- Testing
- Study group of patients will receive standard of care
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Necrotising Enterocolitis Neonatal
Neonatal Laparotomy - A Trial Investigating the Impact of Location of Surgery
This is a pilot randomised trial allocating neonates requiring emergency laparotomy to surgery either on the neonatal unit or in the operating theatre.
- Trial name
- NeoLap (NCT07754435)
- Testing
- IN theatre, ON unit
- Volunteers
- 15 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Idiopathic Scoliosis
Skeletal Muscle and Adipose Tissue Study
The purpose of this research study is to compare the current standard of care for prophylactic Cefazolin administered every 3 hours intravenously with continuous infusion of Cefazolin during pediatric spinal surgery.
- Trial name
- NCT03190668
- Testing
- Bolus dose of Cefazolin, Continuous Cefazolin drip, Paraspinal muscle microdialysis catheters
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
COVID-19, Complication of Anesthesia
Association Between Post-covid Infection Status and Perioperative Morbidity: A Ambispective Cohort Study
With the knowledge of currently transmitted omicron variant being less virulent, over 90 percent of the Chinese population is fully vaccinated, and the Chinese health workers have sufficient experience treating the illness.
- Conditions
- COVID-19, Complication of Anesthesia, Complication of Surgical Procedure, Complication,Postoperative
- Trial name
- NCT05689840
- Testing
- Receiving inpatient surgical intervention
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Peking Union Medical College Hospital
Non Surgical Periodontal Therapy
Effect of Nonsurgical Periodontal Therapy on Salivary Biomarkers Related to Bone Turnover in Smoker and Nonsmoker Periodontitis Patients
1. To assess the alteration in the level of salivary osteopontin (OPN), osteonectin(ON) and histatin-1 following NSPT in smoker and nonsmoker unstable periodontitis patients at different time intervals(one month and three months)…
- Trial name
- NCT06270004
- Testing
- nonsurgical periodontal therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Aortic Dissection
Aortic-Stent-Register
The aims of the aorta-stent-Registry are: participating hospitals (with audit) document all consecutive patients diagnosed with a disease of the distal thoracal aorta that receive one of the following therapies:
- Trial name
- NCT01197651
- Where
- 8 sites in Germany
- Volunteers
- 199 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Genu Valgus
Comparison of Two Surgical Techniques to Treat Knock Knees in Children
Knock knees or genu valgus necessitates in some children corrective surgery with partial closure of the growth plate at level of the knee.
- Trial name
- NCT01641354
- Testing
- Hemiepiphysiodesis
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Aarhus University Hospital
Nasolacrimal Duct Obstruction
Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old
The purpose of this study is: To report the success proportions of simple probing within different age groups of patients under 24 months of age.
- Trial name
- NLD1 (NCT00315289)
- Testing
- Nasolacrimal balloon catheter duct dilation, Nasolacrimal intubation, Simple Nasolacrimal duct probing
- Where
- 2 sites in United States
- Volunteers
- 973 people
- Sponsor
- Jaeb Center for Health Research
Congenital Heart Defect
Use of ROTEM® in Pediatric Cardiac Surgical Patients
Cardiac surgery requiring use of a heart-lung machine, also known as cardiopulmonary bypass (CPB) can induce abnormalities in blood coagulation (clotting) that lead to excessive blood loss during and after operation.
- Trial name
- PedsROTEM (NCT01212289)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Weill Medical College of Cornell University
Ruptured Abdominal Aortic Aneurism
START - Early Thrombocyte Administration to Patients With Ruptured Abdominal Aortic Aneurism
The purpose of this study is to investigate the effect of platelet infusion prior to transfer to a vascular surgical department in patients with a ruptured abdominal aortic aneurism.
- Trial name
- rAAA (NCT01291290)
- Testing
- Platelet
- Where
- Denmark
- Volunteers
- 420 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Dehydration in Children, Fluid Therapy
Boluses of Ringer's in Surgical Kids (BRiSK Study)
Traditional protocols for intravenous fluid administration in children who have undergone a major abdominal or thoracic operation are based on a landmark paper published in 1957 by Holliday and Segar.
- Trial name
- BRiSK (NCT05285371)
- Testing
- Urinalysis (UA), Complete Metabolic Panel (CMP), Glucose Stick Test (d-Stick)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Surgical Procedure, Unspecified
Recovery After Total Intravenous Anesthesia With Ketofol Versus Mixture of Ketofol and Lidocaine for Short Pediatric Surgery
Two hundred children aged 1-12 years undergoing short surgery will be randomized into two groups. Ketofol will be used for induction and maintenance of anesthesia in group l. .Ketofol with lidocaine will be prepared for group ll.
- Trial name
- Lidoketofol (NCT04467424)
- Testing
- ketamine, propofol, ketamine, propofol, lidocaine
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University Hospital of Split
Retinoblastoma, Retinal Neoplasms
Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma
Retinoblastoma is an unusual cancer of early childhood involving tumor is both eyes or, in certain circumstances, one eye only. This condition is the result of an abnormal gene which makes both retinas (the back of the eye)…
- Trial name
- NCT00179920
- Testing
- Carboplatin, VP-16, Local Surgery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pain, Postoperative
Short and Long-term Effects of Surgical Repair of Pectus Deformities
A large number of institutions have reported their early results with minimally invasive repair of pectus excavatum and open repair of pectus carinatum, but only few have addressed the outcomes relevant to the concerns of the…
- Trial name
- NCT01329120
- Testing
- Minimally invasive repair of pectus excavatum, Open surgical repair of pectus carinatum
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
Postoperative Complications, Children
Latin American Surgical Outcomes Study in Pediatric Patients
This prospective, international, multicenter observational study will include hospitals performing pediatric surgery in participating Latin American countries.
- Conditions
- Postoperative Complications, Children, Neonate, Infant
- Trial name
- LASOS-Peds (NCT05934682)
- Testing
- Surgery
- Where
- Brazil
- Volunteers
- 10,000 people
- Sponsor
- University of Sao Paulo
Colorectal Peritoneal Carcinomatosis
Study Comparing the Role of the Laparoscopy Surgical Staging in the Peritoneal Carcinomatosis to Laparotomic Approach
The peritoneum is the second most common site of recurrence in patients with colorectal cancer. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy improve the prognosis of these patients and incorporates…
- Trial name
- COELIOCHIP (NCT02829788)
- Testing
- Non interventional
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.