Clinical trials: Surgical Procedures, Operative
Pain
SPRIX in 0 to 11 Year-Old Patients Undergoing Open Surgical Procedures
The purpose of this study is to evaluate the pharmacokinetics and safety of postoperative administration of SPRIX in pediatric patients (ages 0-11) undergoing open surgical procedures.
- Trial name
- NCT02102516
- Testing
- SPRIX(intranasal ketorolac tromethamine)
- Where
- 4 sites in Poland
- Volunteers
- 45 people
- Sponsor
- Egalet Ltd
Impacted Third Molar Tooth, Healing Surgical Wounds
Evaluation of Hydrogen Peroxide and Hyaluronic Acid (BMG0703) in the Healing of Post-extraction Sites
A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the healing of post-extraction sites of wisdom teeth by film forming action.
- Trial name
- NCT04438434
- Testing
- Filming Formulation of Hydrogen Peroxide and Hyaluronic Acid, Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- University of Milan
Surgical Wound Infection
Relation of Skin Closure Method to Groin Wound Infections After Proximal Femoral Artery Exposure.
This study aims to asses whether the rate of surgical wound infections in vascular surgery procedures involving exposure of the proximal femoral artery can be reduced using a different skin closure technique.
- Trial name
- NCT03468621
- Testing
- Wound closure
- Where
- 3 sites in Finland
- Volunteers
- 300 people
- Sponsor
- Turku University Hospital
Esophageal Atresia
Brazilian Multicenter Study on Esophageal Atresia
Esophageal atresia is a congenital malformation where the esophagus does not form properly, often associated with a tracheoesophageal fistula. This condition requires complex surgical treatment and intensive neonatal care.
- Trial name
- NEOBRA-EA (NCT07210736)
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- University of Sao Paulo General Hospital
Paediatric Surgery, Anaemia
South African Paediatric Surgical Outcomes Study 2
Preoperative anaemia has been shown to be associated with worse outcomes after surgery in both adults and children. Limited research has been done on how common preoperative iron-deficiency anaemia (IDA) is in children and how…
- Conditions
- Paediatric Surgery, Anaemia, Iron Deficiency Anemia, Iron
- Trial name
- SAPSOS2 (NCT05681871)
- Testing
- Ferrous gluconate syrup or ferrous fumarate/folic acid tablets
- Where
- 2 sites in South Africa
- Volunteers
- 755 people
- Sponsor
- University of Cape Town
Laparoscopic Surgery
A Comparative Study of Ventilation Strategies in Different Surgical Positions on Intracranial Pressure and Cerebral Blood Flow During Laparoscopic Surgery
The purpose of this clinical trial is to investigate the effects of laparoscopic surgery in the Trendelenburg and Reverse Trendelenburg positions, and variable tidal volume ventilation (V-VCV), pressure-regulated…
- Trial name
- NCT06805747
- Testing
- Variable tidal volume ventilation (V-VCV), Pressure-regulated volume-controlled ventilation (PRVC), Conventional volume-controlled ventilation (C-VCV)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Inner Mongolia Baogang Hospital
Unilateral Cleft Lip and Palate, Cleft Lip
Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients
The purpose of this study is to evaluate which surgical protocol for treating Unilateral Cleft Lip and Palate (UCLP), a single or two stage repair ( with hard palate late closure) will have less impact in mid facial growth.
- Conditions
- Unilateral Cleft Lip and Palate, Cleft Lip, Cleft Palate, Developmental Disabilities
- Trial name
- NCT02329509
- Testing
- two stage palate surgical repair, One stage Palate Surgical repair
- Volunteers
- 64 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Abdominal Pain
The Effect of Pain Medication in Children With Acute Abdominal Pain and Its Implication Over the Surgeon's Decision
Surgeons are the individuals who will operate on a patient if it is determined to be necessary after they present with abdominal pain.
- Trial name
- NCT00839787
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Carotid Artery Disease
CHOICE: Carotid Stenting For High Surgical-Risk Patients
The purposes of this study is to 1) Provide additional information that the commercially available Abbott Vascular Carotid Stent Systems and Embolic Protection Systems can be used successfully by a wide range of physicians under…
- Trial name
- NCT00406055
- Testing
- RX ACCULINK , RX ACCUNET , XACT , EMBOSHIELD and EMBOSHIELD Nav6
- Where
- United States
- Volunteers
- 18,855 people
- Sponsor
- Abbott Medical Devices
Shoulder Instability
Operative Treatment of Traumatic Anteroinferior Shoulder Instability in Young Male Patients
Glenohumeral joint is prone to instability, i.e. the humeral head may dislocate off the scapular glenoid plate especially in the anteroinferior direction.
- Trial name
- NCT01998048
- Testing
- Latarjet, Bankart
- Where
- 8 sites in Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Intraocular Lens Dislocation
Late Dislocation of Intraocular Lens (IOL) Following Cataract Surgery: an Evaluation of Two Different Surgical Methods
A prospective randomized study on patients with late in the bag intraocular lens (IOL) dislocation, after cataract surgery. To obtain normal visual function, these patients needs surgery.
- Trial name
- NCT01784926
- Testing
- Intraocular lens repositioning by scleral suturing, Intraocular lens exchange with retropupillary iris-claw lens
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- Oslo University Hospital
Congenital Heart Disease
The Effect of 3D Heart Modelling on Family Quality of Life and Surgical Success
Introduction and Objective: In recent years, 3D (three-dimensional) modeling has been added to traditional and effective diagnostic methods such as Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and Echocardiography.
- Trial name
- NCT05852106
- Testing
- Surgical Simulation with 3D Heart Model and Parental Education with "Congenital Heart Disease Parent Education Booklet" and tailored 3D Heart Modeling
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Dexamethasone Administration, Post Extraction Complication
The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar
Evaluating the effectiveness of using a single immediate postoperative intramuscular Dexamethasone injection on pain, swelling, trismus and tissue healing in the first seven days.
- Trial name
- NCT06809855
- Testing
- Dexamethasone
- Where
- Iraq
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Yassir R. Al-khannaq
Gastroschisis
Music Therapy: An Adjunct To Gastroschisis Infants' Care
The investigators hope to determine if music therapy will have beneficial effects on physiologic parameters, behavioral states, and pain scale evaluations in infants with gastroschisis defects and if music therapy promotes…
- Trial name
- MAGIC (NCT01469208)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Surgical Bleeding
Topical Raplixa for Surgical Bleeding in Children
The purpose of the study is to determine if Raplixa plus Gelfoam is better than Gelfoam alone in stopping mild to moderate bleeding in children having surgery.
- Trial name
- NCT02117349
- Testing
- Raplixa, Gelfoam, Rescue treatment
- Where
- 13 sites in United States
- Volunteers
- 55 people
- Sponsor
- Mallinckrodt
Endometriosis, Pelvic Pain
The Safety and Effectiveness of Surgery With or Without Raloxifene for the Treatment of Pelvic Pain Caused by Endometriosis
Many women with lower abdominal pain have endometriosis. Endometriosis is a condition in which the lining of the uterus (endometrium) is found outside of the uterus. The diagnosis of endometriosis is usually made at surgery.
- Trial name
- NCT00001848
- Testing
- Raloxifene
- Where
- United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Glaucoma, Open-Angle
An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)
The purpose of this study is to evaluate the safety and effectiveness of the OMNI® Surgical System in subjects who have undergone canaloplasty and trabeculotomy using OMNI® Surgical System without any concomitant surgery in…
- Trial name
- NCT04872348
- Testing
- OMNI® Surgical System
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- Sight Sciences, Inc.
Surgical Site Infections
Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section
The efficacy and safety of a single dose of ampicillin/sulbactam compared to a single dose of cefuroxime at cord clamp for prevention of postcesarean infectious morbidity has not been assessed.
- Trial name
- NCT01138852
- Testing
- Ampicillin-sulbactam, Cefuroxime
- Volunteers
- 176 people
- Sponsor
- Attikon Hospital
Probiotics, Infant, Newborn
Probiotics Supplementation and Intestinal Microbiome in Neonates With Gastrointestinal Surgery
Congenital defects of the gastrointestinal tract commonly require surgical intervention in the neonatal period. Intestinal surgery during this critical period of microbiome acquisition results in aberrant colonization of the…
- Conditions
- Probiotics, Infant, Newborn, Surgical Procedures, Operative, Gastro-Intestinal Disorder
- Trial name
- ProPS (NCT03266315)
- Testing
- FloraBaby
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Calgary
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