Clinical trials: Surgical Procedures, Operative
Sacrococcygeal Pilonidal Sinus
Effectiveness of Different Surgical Techniques for Curative Treatment of Pilonidal Sinus Disease in the Pediatric Population
Pilonidal sinus disease (PSD) in children is associated with significant morbidity and recurrence risk. Multiple surgical techniques are used, including excision with open healing, primary midline closure, off-midline closure…
- Trial name
- PiloPedia (NCT07470294)
- Testing
- Surgical treatment for pilonidal sinus disease, including various techniques including excision with or without primary closure, or endoscopic techniques.
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers
Laceration of Skin, Injury Skin
Assessment of DAFILON® Suture Material for Skin Closure
In this non-interventional study (NIS) a polyamide non-absorbable suture (Dafilon®) will be evaluated for skin closure in adult and pediatric patients.
- Trial name
- SKINDA (NCT04617041)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 115 people
- Sponsor
- Aesculap AG
Pharmacological-Aggravated Urticaria
Different Methods of Tranexamic Acid Application in Controlling Peri Operative Bleeding in Gynecomastia Surgery
Different Methods of Tranexamic Acid Application in Controlling Peri-Operative Bleeding in Gynecomastia Surgery
- Trial name
- NCT06509256
- Testing
- Tranexamic acid injection
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gastric Cancer
Robotic, Laparoscopic and Open Surgery for Gastric Cancer Compared on Surgical, Clinical and Oncological Outcomes
Gastric cancer represents a great challenge for health care providers and requires a multidisciplinary context in which surgery plays a main role.
- Trial name
- NCT02325453
- Testing
- Robotic Surgery, Laparoscopic Surgery, Open Surgery
- Where
- Italy
- Volunteers
- 7,000 people
- Sponsor
- International Study Group on Minimally Invasive Surgery for Gastric Cancer
Complex Congenital Heart Disease
Support for the Management of Parental Stress in Surgical Resuscitation of Congenital Heart Diseases
Half of children with congenital heart disease develop specific neurodevelopmental disorders. Neurodevelopmental disorders are the leading cause of morbidity in these children.
- Trial name
- Et APRéS Ca (NCT06884046)
- Testing
- Personalized support project
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Keloid
Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181
The objective of the study is to evaluate the initial safety and efficacy of MF-4181, a hydrogel scaffold, in the reduction of the volume, appearance, and/or symptoms associated with keloid scarring in subjects undergoing…
- Trial name
- NCT01446770
- Testing
- Hydrogel scaffold (MF-4181)
- Where
- The Bahamas
- Volunteers
- 19 people
- Sponsor
- Halscion, Inc.
Osteoarthritis
Feasibility Study: Effect of Patient Decision Aids for Total Joint Replacement on Surgical Referrals
Ministries of Health consider wait lists for total joint replacement a top priority. Research priorities to manage wait lists indicate the need to establish benchmarks that consider patient preferences.
- Trial name
- NCT00743951
- Testing
- 1 Patient decision aid, 2 Usual care
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Surgical Site Infection, Groin Hernia
Prophylactic Antibiotics in Groin Hernioplasty
The role of prophylactic antibiotics in preventing surgical site infections (SSI) for clean procedures like groin hernia repair remains controversial.
- Conditions
- Surgical Site Infection, Groin Hernia, Hernioplasty
- Trial name
- NCT07111702
- Testing
- Cefazolin
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Laceration
A Randomized Post-market Study to Evaluate Zip Device Compared to Sutures for Laceration Repair in Pediatrics and Adults
The Zip-009 clinical investigation will enroll 26 paediatric and adult subjects requiring laceration repair and fulfilling the eligibility criteria for the clinical investigation.
- Trial name
- NCT03199456
- Testing
- Zip surgical skin closure device, Standard of Care sutures
- Where
- 2 sites in Sweden
- Volunteers
- 26 people
- Sponsor
- ZipLine Medical Inc.
Obstructive Sleep Apnea of Child
Surgical Versus Nonsurgical Treatment on Quality of Life for Children With Controversial OSA Diagnoses
Obstructive sleep apnea (OSA) is a disease characterized by repeated partial or complete upper airway collapse during sleep, accompanied by arousals or oxygen desaturation.
- Trial name
- NCT03370731
- Testing
- adenotonsillectomy, Nonsurgical management
- Where
- 4 sites in China
- Volunteers
- 60 people
- Sponsor
- Beijing Tongren Hospital
Hemorrhage, Surgical, Tonsillar Bleeding
TEAPOT Study Multisite
After a child has their tonsils removed, sometimes they might bleed which can be a problem. There is a special mist medicine called nebulized tranexamic acid (TXA) that might help stop the bleeding without having to touch the…
- Trial name
- TEAPOT (NCT07565753)
- Testing
- Tranexamic Acid Injectable Product, Normal Saline
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Heart Ischemia, Cerebral Ischemia
Organ Protection by Remote Ischemic Preconditioning for Surgical Treatment of Pediatric Congenital Heart Disease
Cardiac surgery is associated with risk of perioperative inflammation and ischemia leading to cerebral and myocardial morbidity and mortality.
- Trial name
- RIPHeart (NCT01312623)
- Testing
- Remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- University Hospital Schleswig-Holstein
Mucositis Oral
Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis in Peri-implant Mucositis
Peri-implant disease is an inflammatory process of bacterial etiology that can affect the tissues around the implants and can be classified as peri-implant mucositis or peri-implantitis.
- Trial name
- Mucosite prob (NCT04187222)
- Testing
- Mechanical debridements, Bifidobacterium animalis subsp. lactis
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pain, Acute Post-Operative, Ambulatory Surgical Procedures
Machine Learning-Based Prediction of Postoperative Pain After Pediatric Ambulatory Surgery
This study aims to predict pain after surgery in children of ages 1 to 3 years by using computer programming (machine learning). Participant children will be observed before, during, and after surgery.
- Conditions
- Pain, Acute Post-Operative, Ambulatory Surgical Procedures, Pediatric Pain, Pediatric Patient (1m-21y)
- Trial name
- NCT07274995
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Anxiety, Fear
Smartphone-Based Cartoon Distraction During Cast Removal in Children
Cast removal can cause considerable fear and anxiety in children despite being a generally painless procedure. This randomized controlled trial evaluated whether watching a cartoon on a smartphone during circumferential…
- Trial name
- CAST-REMOVE (NCT07842627)
- Testing
- Smartphone-Based Cartoon Distraction, Standard Cast Removal Care
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Caner Oguk
Peer Review, Research
Scheduled Elective Surgical Case Cancellation in Siriraj: Evaluation and Identification of the Reasons
A retrospective cross-sectional analytic study to evaluation and identification of the reasons about Scheduled elective surgical case cancellation in Siriraj Hospital, reason of cancellation will be extracted from hospital…
- Trial name
- NCT02816281
- Where
- Thailand
- Volunteers
- 2,760 people
- Sponsor
- Siriraj Hospital
Scoliosis
Surgical Outcomes Using Variable Rod Diameters in the Treatment of Idiopathic Scoliosis
There are two rod sizes routinely used for the correction of juvenile and adolescent idiopathic scoliosis, 5.5mm and 6.35mm, typically stainless steel.
- Trial name
- NCT00510575
- Testing
- Spinal rod
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Shriners Hospitals for Children
Osteoarthritis, Knee, Arthropathy of Knee
Comparative Outcomes Between Image-based Versus Imageless Robot-assisted Unicondylar Knee Arthroplasty
This prospective cohort study was conducted with the aim of comparing relevant clinical outcomes which included intra (surgical time and blood loss), post-operative outcomes (range of motion, function, complications and…
- Trial name
- NCT03954912
- Testing
- MAKO assisted unicondylar knee arthroplasty, NAVIO assisted unicondylar knee arthroplasty
- Volunteers
- 33 people
- Sponsor
- Ramathibodi Hospital
Liver Transplantation
Application of in Vivo Splitting Technique in Adult Liver Transplantation
The feasibility of split liver transplantation (SLT) remains controversial. This study aimed to evaluate the outcomes of SLT in adult recipients and to identify specific areas of improvements.
- Trial name
- NCT06925828
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Stroke, Acute, Stroke, Complication
Feasibility of Stroke Screening Tools in Cardiac Surgery Patients
Patients undergoing cardiac surgery have a higher risk of postoperative stroke than patients undergoing non-cardiac surgery. Our ability to detect postoperative stroke in this population lags behind other postoperative…
- Conditions
- Stroke, Acute, Stroke, Complication, Surgical Complication
- Trial name
- PESST-Cardiac (NCT05447728)
- Testing
- Modified National Institutes of Health Stroke Scale, PRESTO
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
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