Clinical trials: Surgical Procedures, Operative
Prostate Cancer Surgery
Laparoscopic Vs. Open Prostatectomy Outcomes
This study is aimed at discovering the differences in outcomes, regarding quality of life issues(continence, impotence) of patients who have had either laparoscopic or open surgical technique for prostate cancer.
- Trial name
- NCT00695773
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Lahey Clinic
Cesarean Wound Disruption With Postnatal Complication
Impact of Preoperative Bathing on Post Caesarean Section Surgical Site Infection
Surgical site infection (SSI) is the commonest hospital-acquired infection globally, and prevalence is much higher in the low-income countries. Caesarean delivery carries a 5-20 fold risk for developing postpartum sepsis.
- Trial name
- SSI-MUST (NCT03544710)
- Testing
- preoperative bathing with antiseptic
- Where
- Uganda
- Volunteers
- 96 people
- Sponsor
- Mbarara University of Science and Technology
Postoperative Care/Methods, Drainage/Methods
The Effect of Manual Lymphatic Drainage on Swelling After Orthognathic Surgery - a Qualitative and 3D Facial Analysis.
Introduction / background Orthognathic surgery is an operation in which one or both jaws are fixed in a more favorable position performed by an osteotomy.
- Conditions
- Postoperative Care/Methods, Drainage/Methods, Edema/Prevention & Control, Orthognathic Surgical Procedures/Adverse Effects
- Trial name
- NCT03682159
- Testing
- manual lymphatic drainage
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Ghent
Breast Cancer
Trial Comparing Perioperative Care for Breast Cancer Patients at a Patient Hotel vs a General Surgical Ward
To explore the possible benefit of a patient hotel, a study was undertaken to test the hypothesis that perioperative care at a patient hotel would be valued better than care in a general ward.
- Trial name
- NCT02403973
- Testing
- IN2005E
- Volunteers
- 151 people
- Sponsor
- Danderyd Hospital
Solid Pseudopapillary Tumor
Safety of EUS-FNA for Pancreatic Solid-Pseudopapillary Neoplasm (SPN) Before Surgical Resection: the SPN-GRAPHE Series
Solid-pseudopapillary neoplasm (SPN) is a rare type of pancreatic neoplasm. A cytopathological diagnosis is often mandatory before performing surgical resection.
- Trial name
- SPN-GRAPHE (NCT03749941)
- Volunteers
- 149 people
- Sponsor
- Société Française d'Endoscopie Digestive
Fibula / Surgery, Surgical Flaps
Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
Stock reconstruction plates have been used for decades and represent a tried-and-true alternative to custom plating. Stock plates are readily available, are cost effective, and can be accurately bent before surgery, particularly…
- Conditions
- Fibula / Surgery, Surgical Flaps, Computer-Aided Design, Mandibular Reconstruction* / Methods
- Trial name
- NCT05672056
- Testing
- Computer guided placement of a stock plate pre-bent on a 3D printed model
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ultrasound Therapy; Complications, Transverse Diameter of Cricoid Cartilage
Ultrasound Measurements of Circular Cartilage Transverse Diameter
This study with children under 1 age of elective surgery as the research subjects, according to the cross diameter, compared with the traditional method of empirical catheter model, analyze the success rate, completion time of…
- Conditions
- Ultrasound Therapy; Complications, Transverse Diameter of Cricoid Cartilage, Endotracheal Intubation, Children
- Trial name
- NCT05273294
- Testing
- Portable color Doppler ultrasound system
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shengjing Hospital
Incisional Surgical Site Infections
Total Occlusive Ionic Silver-containing Dressing vs Mupirocin Ointment Application vs Conventional Dressing in Elective Colorectal Surgery: Effect on Incisional Surgical Site Infection
The patients were randomized into 3 groups: those patients undergoing a ionic silver-containing dressing (ISD) (Group 1), those undergoing a Mupirocin ointment application (MOA) (Group 2) and those using a conventional dressing…
- Trial name
- NCT02267122
- Testing
- ionic silver-containing dressing, Mupirocin ointment application
- Volunteers
- 147 people
- Sponsor
- Hospital General Universitario Elche
Congenital Heart Disease
Coronary Artery Assessement by TEE in Congenital Heart Disease
This study aims to establish normal coronary artery pulse Doppler flow patterns and velocities using transoesophageal echocardiography (TEE) in patients with a variety of congenital heart disease.
- Trial name
- NCT04194502
- Testing
- Transesophageal echocardiogram (TEE)
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- The Hospital for Sick Children
Nephrolithiasis, Kidney Stone
Observational Approach Versus Surgical Intervention for Stones
The aims of the Observational Approach versus Surgical Intervention for Asymptomatic Stone (OASIS) trial are: 1) to determine whether observation compared to upfront surgery results in less healthcare-related life disruption due…
- Trial name
- OASIS (NCT07718802)
- Testing
- Surgery, Observation
- Where
- 4 sites in United States
- Volunteers
- 1,658 people
- Sponsor
- Children's Hospital of Philadelphia
Mitral Regurgitation (MR), Pediatric Cardiac Surgery
A Prospective Multicenter Cohort Study on Surgical Treatment Strategies for Pediatric Mitral Regurgitation
This prospective, multicenter cohort study aims to evaluate the outcomes of surgical repair for pediatric mitral regurgitation (MR) in China.
- Trial name
- NCT07284212
- Testing
- conventional mitral valve repair, standardized mitral valve repair
- Where
- China
- Volunteers
- 427 people
- Sponsor
- China National Center for Cardiovascular Diseases
Epilepsy
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
Objectives: The overall study objective is to compare the sensitivities and specificities of morphometric analysis techniques using structural MRI images based on pre- and postsurgical localization of epileptic foci in patients…
- Trial name
- NCT02107989
- Testing
- MRI, MEG
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Vaginal Prolapse
Surgical Outcomes of Vaginal Prolapse Repair With Elevate
The purpose of this study is to evaluate outcomes in patients having vaginal prolapse repair with the Elevate prolapse repair kit and compare these outcomes to patients who had a repair with Prolift. .
- Trial name
- NCT01190618
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- Larry Sirls
Pupillary Block After DMEK, Laser Iridotomy / Surgical Iridectomy
Impact of Iridotomy/Iridectomy Size on Postoperative Pupillary Block and Dysphotopsia Following DMEK
Descemet membrane endothelial keratoplasty (DMEK) is the standard surgical treatment for corneal endothelial disorders. A postoperative pupillary block may occur despite routine preoperative laser iridotomy or intraoperative…
- Conditions
- Pupillary Block After DMEK, Laser Iridotomy / Surgical Iridectomy, Dysphotopsia, Descemet Membrane Endothelial Keratoplasty (DMEK)
- Trial name
- NCT07577635
- Testing
- Anterior Segment Optical Coherence Tomography (AS-OCT), Dysphotopsia Questionnaire
- Volunteers
- 100 people
- Sponsor
- University of Leipzig
Hemophilia
Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery
This is an interventional, prospective, international, multicenter, single-arm, Phase 3, and sequential efficacy and safety study in adolescents and adults with congenital hemophilia A or B with inhibitors to factor VIII (FVIII)…
- Trial name
- SCOPE HIM (NCT05695391)
- Testing
- Coagulation Factor VIIa (Recombinant)
- Where
- 15 sites in United States, Malaysia and 4 more
- Volunteers
- 2 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Clift Lip, Cleft Palate
Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone)
Study Objective The objective of this study was to evaluate and compare postoperative pain and hospital costs in pediatric patients with cleft lip and palate undergoing alveolar bone grafting surgery.
- Conditions
- Clift Lip, Cleft Palate, Alveolar Bone Loss, Postoperative Pain
- Trial name
- NCT07734974
- Testing
- Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Sirio-Libanes
Chorioamnionitis, Pregnancy Complications, Infectious
Closure of Skin in ChorioAmnionitis Research Pilot Study
The purpose of the CSCAR pilot study is to improve the design of a full-scale trial by determining the patient recruitment rate and participation rate.
- Conditions
- Chorioamnionitis, Pregnancy Complications, Infectious, Complications; Cesarean Section, Postoperative Complications
- Trial name
- CSCAR (NCT01988168)
- Testing
- Suture closure, Staples closure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Pediatric Liver Transplanted Recipients, Healthy Donors
Living Donor Liver Transplantation in Children
Evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein reconstruction, ABO-compatibility and impact of maternal donation on graft acceptance.
- Trial name
- NCT02124382
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Myocardial Bridge of Coronary Artery
Correlates of Left Ventricular Global Longitudinal Strain and Surgical Intervention on Myocardial Bridges
To examine the changes in left ventricular (LV) global longitudinal strain (GLS), using two-dimensional speckle tracking analysis, after left anterior descending (LAD) unroofing, in myocardial bridges (MBs) refractory to optimal…
- Trial name
- NCT04082546
- Testing
- Surgical unroofing of muscle-briged coronary artery
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Endocarditis
Outcomes Following Medical or Surgical Management of Endocarditis
Infective endocarditis is a rare disease, and while there have been several large reviews of the incidence of endocarditis in the pediatric patient population, relatively little has been published regarding the short and…
- Trial name
- NCT00166023
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
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