Clinical trials: Surgical Wound Infiltration
Breast Cancer, Pain
CWI and Discharge After Breast Cancer Surgery
The objectives of this work are threefold: 1. To evaluate the analgesic efficacy of CWI in women discharged within 23 hours of major breast cancer surgery 2.
- Trial name
- NCT02897934
- Testing
- Bupivacaine continuous infusion
- Where
- Ireland
- Volunteers
- 10 people
- Sponsor
- University College Cork
Appendectomy, Laparoscopy
TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study
Effectiveness of the TAP block compared to wound infiltration in controlling pain after laparoscopic appendectomy in children
- Conditions
- Appendectomy, Laparoscopy, Anesthesia, Conduction, Child, Preschool
- Trial name
- NCT04294537
- Testing
- TAP Block, LIA local infiltration, General anesthesia
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Cleft Palate Children, Block
Suprazygomatic Nerve Block vs Surgical Site Infiltration in Cleft Palate Repair
The aim of this study is to evaluate the efficacy and duration of effect of bupivacaine given preoperatively as a bilateral suprazygomatic maxillary nerve block and to compare it with peri-incisional infiltration with the same…
- Trial name
- NCT03799068
- Testing
- suprazygomatic maxillary nerve block, surgical site infiltration
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain, Spinal Fusion
Postoperative Pain Control Using Local Wound Infiltration in Adolescent Idiopathic Surgery
Non-opioid methods of pain management following posterior spinal fusion (PSF) have become increasingly popular given the rise of opioid abuse and opioid-related deaths.
- Trial name
- NCT04730531
- Testing
- Local infiltration with 0.25% bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Cardiac Conditions
Liposomal Bupivacaine Pharmacokinetic Study After Median Sternotomy Incision Infiltration in a Pediatric Cardiac Surgery
The purpose of the study is to determine the plasma concentration of bupivacaine at various time points after Exparel (bupivacaine liposome injectable suspension, Pacira Pharmaceuticals, Inc., Parsippany, NJ) is injected…
- Trial name
- CohortI-II (NCT04685421)
- Testing
- Bupivacaine liposome
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Postoperative Pain
Intraoperative Local Anaesthetic and Postoperative Pain
Background: Intraoperative wound infiltration with local anaesthetic is commonly used. Apart from the obvious immediate action it has been supported that a possible down regulation of pain receptors may lead to longer effects.
- Trial name
- Pain-1 (NCT02171299)
- Testing
- Wound infiltration with local anaesthetic, Ropivacaine
- Where
- Greece
- Volunteers
- 400 people
- Sponsor
- Hellenic Red Cross Hospital
Hip Dysplasia
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1.
- Trial name
- PILA PAO (NCT06519955)
- Testing
- Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Michael C Willey
Healing Surgical Wounds
Local Wound Infiltration Versus Caudal Block on Wound Infection and Healing in Paediatrics Inguinal Herniotomy
The aim of the present study is to assess effect of local wound infiltration in comparison with caudal block by bupivacaine 0.25% after inguinal herniotomy in pediatrics on: Wound infection and healing (primary outcome) and…
- Trial name
- NCT03563625
- Testing
- Caudal block, Wound infiltration, Bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- University of Alexandria
Postoperative Pain
Caudal Block v/s Local Wound Infiltration for Pain Control in Pediatric Patients After Operation for Inguinal Hernia
This randomized controlled trial aims to compare the analgesic efficacy of local wound infiltration with Ropivacaine versus Caudal Block with Ropivacaine in pediatric patients undergoing surgery for inguinal hernia
- Trial name
- NCT07747038
- Testing
- Caudal Block with Ropivacaine Intervention, Local Wound Infiltration with Ropivacaine Intervention, Intravenous Paracetamol Suspension Intervention
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Fatima Memorial Hospital
Anesthesia, Caudal
Caudal Block Versus Local Wound Infiltration for Inguinal Procedures
Single-centre observational study to analyse whether there is a difference in post-operative pain scores and set up time when comparing caudal block with local wound infiltration
- Trial name
- NCT04590027
- Volunteers
- 86 people
- Sponsor
- University Hospital Tuebingen