Clinical trials: Symptom Management
Infant Mortality, Under-two Mortality
Integrating Pediatric Care Delivery in Rural Healthcare Systems
Globally, over seven million children under the age of five die each year, although a suite of interventions-safe delivery care, neonatal care and resuscitation, and management of childhood diarrhea, malnutrition, and…
- Trial name
- NCT02331082
- Testing
- Structured Quality Improvement, Chronic Care Model, Integrated Electronic Medical Record
- Where
- 2 sites in Nepal
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Possible
Newborn Resuscitation, Severe Malnutrition
Enhancing Pediatric Acute Care Through Adaptive E-Learning and In-Person Skills Practice in Tanzania
The goal of this clinical trial is to evaluate whether the integration of in-person skills practice (ISP) with an adaptive e-learning platform can improve refresher learning progress (RLP) among healthcare providers in pediatric…
- Conditions
- Newborn Resuscitation, Severe Malnutrition, Severe Malaria, Severe Pneumonia
- Trial name
- PACE (NCT06635733)
- Testing
- Rhapsode Capable™ Platform (Intervention Group), Paper-based ISP (Control Group)
- Where
- Tanzania
- Volunteers
- 100 people
- Sponsor
- Stanford University
Postoperative Pain
Comparison of Postoperative Pain Management in Patients Undergoing Laparoscopic Colorectal Surgery Under Enhanced Recovery After Surgery (ERAS) Program, Laparoscopic Colorectal Surgery Without ERAS and Open Colorectal Surgery
This is a retrospective study to compare postoperative pain intensity in patients going laparoscopic colorectal surgery with Enhanced Recovery after Surgery (ERAS), without ERAS and open colorectal surgery.
- Trial name
- NCT04997174
- Testing
- Celecoxib
- Where
- Thailand
- Volunteers
- 162 people
- Sponsor
- Prince of Songkla University
Circulatory Failure (Shock)
Fluid-responsiveness in Children Ventilated With LOW Tidal Volume - The FLOW Study.
In this study of diagnostic accuracy, the investigators aim to validate a fluid-responsiveness test in critically ill children mechanically ventilated with low tidal volume.
- Trial name
- FLOW (NCT07494643)
- Testing
- Echocardiographic
- Where
- 6 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Thrombocytopenia
Perioperative Eltrombopag in Patients With Inherited Thrombocytopenia
The objective of the study is to estimate the response to eltrombopag based on platelet count increase above a safety level of 80 G/L and lack of requirement for pre-, per- and post-operative administration of platelet…
- Trial name
- ELPOT (NCT03638817)
- Testing
- Eltrombopag
- Where
- 25 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Toulouse
Care Giver, Recurrent Malignant Neoplasm
PCRC-Supported Legacy Intervention in Pediatric Palliative Care
This trial studies how well a web-based legacy intervention works in improving the quality of life in caregivers and younger patients with cancer that has come back (recurrent) or does not respond to treatment (refractory).
- Conditions
- Care Giver, Recurrent Malignant Neoplasm, Refractory Malignant Neoplasm
- Trial name
- NCT04059393
- Testing
- Internet-Based Intervention, Best Practice, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Palliative Care, Primary Care
Latin America Network for Primary Palliative Care
Palliative care is the holistic care provided to individuals and their families who experience health related suffering related to life-limiting conditions.
- Conditions
- Palliative Care, Primary Care, Primary Care Physician
- Trial name
- LANPPC (NCT07436026)
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- University of Edinburgh
Hypotension, Fluid Overload
Inferior Venacava Ultrasound to Guide Fluid Management for Prevention of Hypotension After Spinal Anesthesia.
Hypotension is common during spinal anesthesia and contributes to underperfusion and ischemia. Severe episodes of intraoperative hypotension is an independent risk factor for myocardial infarction, stroke, heart failure, acute…
- Trial name
- NCT04736498
- Testing
- Inferior venacava Ultrasonography (IVC USG) guided fluid management
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Tribhuvan University, Nepal
Distraction Methods, Nursing Care
Effects of Cartoons & Interactive Storytelling on Fear and Comfort in 6-9 Year Olds During Nebulizer Treatment
Fear and anxiety experienced by children during inhalation therapy (using a nebulizer or vaporizer) are key factors that make treatment compliance difficult and reduce the quality of care.
- Trial name
- NCT07516249
- Testing
- Cartoon Watching, Interactive storytelling synchronized with breath, Standard Group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Virtual Reality, Pain
Virtual Reality vs Passive Distraction for Pain Management
Background: Outpatient pediatric orthopedic procedures such as percutaneous pins removal and sutures are considered painful and generate significant stress and anxiety in children.
- Conditions
- Virtual Reality, Pain, Pain Perception, Pain Management
- Trial name
- NCT03680625
- Testing
- Passive Distraction, Virtual Reality Distraction
- Where
- 3 sites in Canada
- Volunteers
- 188 people
- Sponsor
- St. Justine's Hospital
Food Allergy in Children, Caregiver Burnout
The Psychosocial Outcomes in Caregivers of Children With Food Allergy
The purpose of this study is to evaluate use of a mobile application (also commonly referred to as an app) designed to support caregivers of children with newly diagnosed food allergy. This study has 2 phases.
- Conditions
- Food Allergy in Children, Caregiver Burnout, Psychosocial Problem, Family Research
- Trial name
- FASST (NCT04512924)
- Testing
- Enhanced mobile app with standard of care and education, Enhanced mobile app with standard of care, education and support resources
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Laparoscopic Renal Surgery, Pain Management
Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al.
- Conditions
- Laparoscopic Renal Surgery, Pain Management, Nerve Block
- Trial name
- NCT02841982
- Testing
- single-injection QLB(quadratus lumborum block), Philip CX50 Ultrasound Scanner, PAJUNK StimuLong
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Cui Xulei
Obesity, Childhood
Family, Responsibility, Education, Support, and Health for Food Responsiveness
The objective of this proposed study is to compare Regulation of Cues (ROC), Family-Based Treatment (FBT), ROC+ nutrition education and reducing energy intake (ROC+) and a health education comparator (HE) for children with…
- Trial name
- FRESH-FR (NCT06207110)
- Testing
- Regulation of Cues, Family Based Behavioral Treatment, Regulation of Cues +
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Stress Urinary Incontinence
Trial Comparing TVT SECUR System and Trans Vaginal Obturator Tape for Surgical Management of Stress Urinary Incontinence
To compare the efficacy and complications of the TVT SECUR system (TVT S) and trans-vaginal obturator tape (TVT-O) procedures for the surgical management of female stress urinary incontinence.
- Trial name
- NCT00527696
- Testing
- transvaginal obturator tape
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Body Weight Changes, Eating Disorder Symptom
Body Weight Regulation, Disordered Eating Behaviour, and Experiences of Sexual Harassment in Female Martial Art Athletes
Athletes in martial arts compete in categories separated by body weight, hence, many athletes need to adjust their habitual body weight during periods with competition preparation.
- Conditions
- Body Weight Changes, Eating Disorder Symptom, Sexual Harassment, Covid19
- Trial name
- FMAB (NCT04559542)
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Pain Management, Pain Assessment
Effectiveness and Implementation of a Clinical Pain Management Dashboard for the NICU
This study protocol describes a type 1 hybrid effectiveness-implementation study evaluating a clinical decision support dashboard for neonatal pain management in a tertiary NICU.
- Conditions
- Pain Management, Pain Assessment, Neonatal Intensive Care, Implementation Research
- Trial name
- NCT07629661
- Testing
- Implementation of clinical pain management dashboard
- Where
- Netherlands
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Obesity
The Added Value of Telephone Follow Up and Home Visits in Helping Children to Grow Up Healthy
Leading medical organizations have called on primary care pediatricians to take a central role in the prevention of childhood obesity.
- Trial name
- NCT01973153
- Testing
- Brief Motivational Counseling (BMC), Brief Motivational Counseling Plus Phone Calls (BMC + Phone), Brief Motivational Counseling Plus Home Visits (BMC + Home)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Scoliosis, Regional Anesthesia
Erector Spine Plane (ESP) Block for Analgesia in Pediatric Scoliosis Surgery
Postoperative pain after scoliosis correction surgery is severe and usually requires long-term intravenous opioid therapy. Local anesthetic options are limited and include intrathecal opioids and epidural analgesia.
- Conditions
- Scoliosis, Regional Anesthesia, Pediatric Anesthesia, Orthopedic Disorder of Spine
- Trial name
- NCT05944393
- Testing
- Ropivacaine 0.2% Injectable Solution, Normal saline 0.9% Injectable Solution
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Poznan University of Medical Sciences
Obesity
Chrono-Fasting in Overweight and Obese Adolescents
Childhood and adolescent obesity represents a major global public health concern, with a steadily increasing prevalence over recent decades, accompanied by a rise in metabolic disorders among younger populations.
- Trial name
- ChronoFasting (NCT07759414)
- Testing
- Early TRF, late TRF, Control
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- University of Thessaly
Pain Management
Neurofeedback-EEG-VR System for Non-opioid Pain Therapy
This study will assess the feasibility of developing the Neurofeedback-EEG-VR (NEVR) system for non-opioid pain therapy. Subjects suffering from pain will undergo sessions involving VR and Neurofeedback training and their pain…
- Trial name
- NEVR (NCT04551092)
- Testing
- NEVR
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Quantum Applied Science & Research, Inc.
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