Clinical trials: Symptoms, Affective
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Depression
Examination of a Soy-Based Supplement for Major Depression
The purpose of this study is to find out if the soy-based dietary supplement Novasoy (Registered Trademark) is effective for the short-term treatment of clinical depression.
- Trial name
- NCT00042380
- Testing
- Novasoy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Disorders, Mood Disorders
A Study of the Effectiveness and Safety of Topiramate in the Treatment of Patients With Bipolar Disorder
The primary purpose of this study is to evaluate the effectiveness and safety of topiramate compared with placebo in the treatment of acute manic or mixed episodes in patients with Bipolar I Disorder.
- Conditions
- Bipolar Disorders, Mood Disorders, Affective Disorders, Psychotic
- Trial name
- NCT00240721
- Testing
- topiramate
- Volunteers
- 363 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Neurodegenerative Disease, Dementia
Cognition and Affective Research in China
This is a prospective cohort study of patients with cognitive impairment mood disorders and behavioral disorders. Comprehensive baseline and longitudinal follow-up assessments include clinical and epidemiological data, cognitive…
- Conditions
- Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease
- Trial name
- CARE (NCT07833267)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Bipolar Disorder, Anxiety Disorders
Double-Blind Placebo-Controlled Trial of Riluzole in Pediatric Bipolar Disorder
Pediatric Bipolar Disorder (BD) is uncommon in children. Its symptoms include periods of manic behavior (being overly happy or giddy, feeling grandiose, feeling a decreased need for sleep, having too much energy, moving more than…
- Conditions
- Bipolar Disorder, Anxiety Disorders, Bipolar Affective Disorder, Bipolar Depression
- Trial name
- NCT00805493
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Disorder
Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
A long-term study of current treatments for bipolar disorder, including medications and psychosocial therapies.
- Trial name
- NCT00012558
- Testing
- lithium, valproate, bupropion
- Where
- 11 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- National Institute of Mental Health (NIMH)
Alexithymia, Epilepsies
Alexithymia and Emotional Dysregulation in a Cohort of Pediatric Patients With Epilepsy
Epilepsy is a neurological condition characterized by recurrent seizures. Children and adolescents with epilepsy may also experience emotional and psychological difficulties, including problems identifying and describing their…
- Trial name
- ALEDE (NCT07879976)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Giannina Gaslini
Major Depressive Episode
Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders
Despite international efforts to identify biomarkers of depression, none has been transferred to clinical practice, neither for diagnosis, evolution, nor therapeutic response.
- Trial name
- SoPsy-SoSad (NCT05866991)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Schizophrenia, Bipolar Disorder
Skills for Wellness
Severe mental illness such as schizophrenia and mood disorders typically develops at a young age and can cause life-long disability. Currently available treatments cannot cure severe mental illness.
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depression
- Trial name
- SWELL (NCT01980147)
- Testing
- maCBT
- Where
- 2 sites in Canada
- Volunteers
- 360 people
- Sponsor
- Nova Scotia Health Authority
Depressive Disorder
An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
This study will examine whether a highly specific and powerful 5-hydroxytryptamine 2A (5-HT2A) antagonist, M100907, combined with escitalopram, is responsible for an antidepressant effect.
- Trial name
- NCT00070694
- Testing
- MDL100.907
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- National Institute of Mental Health (NIMH)
Social Functioning, Alexithymia and Sense of Coherence , Bipolar Disorders
The Effect of Physical Exercises Program on Social Functioning, Alexithymia and Sense of Coherence Among Patients With Bipolar Disorders
The aim of this study is to: Investigate the effect of applying physical exercises program on social functioning, alexithymia and sense of coherence among patients with bipolar disorders Research Hypotheses Clients who…
- Trial name
- NCT05741281
- Testing
- Physical exercises program
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Bone Diseases, Metabolic, Depression, Involutional
Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression
In this study researchers would like to learn more about the low levels of bone mineral density seen in approximately half of women in their forties diagnosed as currently having or previously had depression.
- Conditions
- Bone Diseases, Metabolic, Depression, Involutional, Osteoporosis
- Trial name
- NCT00001916
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Brain Damage, Chronic, Cerebellar Cognitive Affective Syndrome
DTI & Tractography in Pediatric Tumor Surgery
The goal of this project will be to demonstrate that Synaptive Medical's Diffusion Tensor Imaging(DTI) product functionality used in pre-operative planning and intraoperative surgical navigation, improves clinical outcomes…
- Conditions
- Brain Damage, Chronic, Cerebellar Cognitive Affective Syndrome, Cerebellar Mutism
- Trial name
- NCT02810626
- Testing
- BrightMatter™ products
- Volunteers
- 24 people
- Sponsor
- London Health Sciences Centre
Behavior Problem, Development Delay
Norwalk Feasibility Study
The purpose of this study is two-fold: 1) to examine the feasibility of the Drop-In model of Family Nurture Intervention (FNI); and 2) to collect pilot data concerning the mother's response to the Drop-In model of FNI and short…
- Conditions
- Behavior Problem, Development Delay, Emotional Disturbances, Family Conflict
- Trial name
- NCT04048720
- Testing
- Family Nurture Intervention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Depression, Bipolar Affective Disorder
Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
The project proposes to develop a digital product based on cognitive behavioral therapy for the assisted treatment of depression.
- Conditions
- Depression, Bipolar Affective Disorder, Schizophenia Disorder, Psychiatric &Amp;or Mood Disorder
- Trial name
- NCT06831435
- Testing
- a digital product based on CBT
- Where
- China
- Volunteers
- 325 people
- Sponsor
- Peking University
Eating Disorder, Emotional Disorder
Integrative Cognitive-Affective Therapy for Adolescent Eating Disorders
Recently, Integrative Cognitive-Affective Therapy (ICAT), a novel intervention for bulimia nervosa (BN) and binge eating disorder (BED) that targets emotion regulation deficits, has shown promise in reducing eating disorder…
- Trial name
- ICAT-A (NCT03324724)
- Testing
- Integrative cognitive-affective therapy for adolescents (ICAT-A)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Hyperemesis Gravidarum, Temperament
Assessment of the Relationship Between Affective Temperament and the Severity of Nausea and Vomiting in Early Pregnancy
In this study, the investigators aimed to research the relationship between affective temperament with the severity of the symptoms of nausea and vomiting in early pregnancy.
- Conditions
- Hyperemesis Gravidarum, Temperament, Morning Sickness
- Trial name
- NCT02541682
- Testing
- TEMPS-A (Temperament Evaluation of Memphis, Pisa, Paris and San Diego Auto-questionnaire)
- Where
- Turkey (Türkiye)
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemalpasa Government Hospital
Somatic Symptom Disorder
Alexithymia and Attachment Style in Patients With Somatic Symptoms
To evaluate whether emotional awareness, attachment style and the ability to abstract and symbolize (IQ) influence the appearance of somatic symptoms.
- Trial name
- NCT05666921
- Testing
- psychological assessment
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Meyer Children's Hospital IRCCS
Emotional Disturbance
Students, Parents, and Teachers On Track: Intervention Development for Youth With Emotional Disturbance
The purpose of the On Track intervention is to address a need raised by a day-treatment school in Lane County: Support for students transitioning from the day-treatment school (Lane School) to their district middle schools.
- Trial name
- OnTrack (NCT01705431)
- Testing
- On Track
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Oregon Social Learning Center
Emotional Disturbances, Behavior Disorders
The Safety-Net Approach
The Safety-Net project, is intended to disrupt disparities in mental health treatment access for children at-risk for childhood trauma (ACEs) and/or serious emotional disturbance (SED).
- Conditions
- Emotional Disturbances, Behavior Disorders, Mental Disorders, Severe
- Trial name
- Safety-Net (NCT04675567)
- Testing
- Safety-Net Care Team Model
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Cambridge Health Alliance