Clinical trials: TEETH EXTRACTION
Gingival Cleft, Orthodontic Space Closure
Gingival Cleft Development at Two Time Points of Canine Retraction
The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients.
- Trial name
- NCT07210762
- Testing
- Early space closure, Delayed space closure
- Where
- Pakistan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bahria University
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Molar, Third, Wisdom Teeth
Effect of Hilotherm Therapy on Post-operative Pain and Swelling Following Surgical Wisdom Tooth Removal
This study evaluates the efficacy of Hilotherm therapy on the incidence of swelling and pain following the surgical removal of lower wisdom teeth.
- Trial name
- NCT02284841
- Testing
- Hilotherm cooling face mask
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Wisdom Tooth Avulsion
Non-closure of Alveoli After Avulsion of Wisdom Teeth
The main objective of this study is to evaluate postoperative pain (measured by visual analogue scale (VAS) on day 2 post surgery) in patients operated for avulsion of four wisdom teeth under general anesthesia and for whom the…
- Trial name
- AlvéCare (NCT02583997)
- Testing
- Suturing of lower alveoli, Non suturing of lower alveoli
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Implant, Tooth Extraction
Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques
The aim is to comparatively evaluate the soft tissue volume changes that occur after tooth extraction and immediate dental implant placement using two different surgical techniques.
- Conditions
- Dental Implant, Tooth Extraction, Bone Resorption
- Trial name
- NCT04803110
- Testing
- Dental implant placement after tooth extraction
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Aula Dental Avanzada
Dental Sedation, Passive Smoking
The Effects of Passive Smoking on Vital Signs, Anxiety, and Recovery Times in Children Undergoing Primary Tooth Extraction Treatment Under Sedation
The aim of this clinical study is to evaluate the effects of passive smoking on the vital parameters of children undergoing primary tooth extraction under sedation and to assess their anxiety levels throughout the process until…
- Trial name
- NCT06780189
- Testing
- Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking, Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Not Exposed to Passive Smoking
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Reversible Pulpitis, Pulpitis
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group…
- Conditions
- Reversible Pulpitis, Pulpitis, Caries,Dental, Caries Class I
- Trial name
- NCT04365270
- Testing
- Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tooth Extraction Status Nos
Tooth Extraction With Deep Sedation in Children: A Retrospective Study
In this study it's aimed to evaluated the patients in whom dental local anesthetic attempts were failed due to anxiety or fear and referred to our clinic for tooth extraction with deep sedation.
- Trial name
- NCT02200861
- Where
- Turkey (Türkiye)
- Volunteers
- 885 people
- Sponsor
- TC Erciyes University
Dental Pain
Maxi-Analgesic Phase 2 Study to Compare the Analgesic Effects in Different Dosing Groups to Treat Teeth Extraction Pain
The aim of the study is to examine the dose response relationship in the treatment of dental pain (teeth extraction) for the different potential doses of the investigational drug, i.e.
- Trial name
- NCT01104844
- Testing
- Full Dose Strength, Quarter dose strength, Half dose strength
- Where
- United States
- Sponsor
- AFT Pharmaceuticals, Ltd.
Dental Plaque
Supragingival Plaque Removal With and Without Dentifrice
Purpose: The aim of this study was to compare the efficacy of dental biofilm removal by brushing with and without conventional toothpaste.
- Trial name
- NCT01986972
- Testing
- Toothbrushing With Dentifrice, Toothbrushing Without Dentifrice
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Franciscan University Center
Cerebral Palsy
"Comparing the Plaque Removal Ability of Two Different Toothbrushes Among School Going CP Children
It was an intervention utilizing two toothbrushes on school going cerebral palsy children age (6 -18 yrs). The triple head tooth brush and single head brush was provided to parents along with dental health education to their…
- Trial name
- NCT05536648
- Testing
- Comparing the plaque removal ability of triple head tooth brush versus single head tooth brush among school based cerebral palsy children: A Randomized Control Trial
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Cases That Need Extraction of Teeth in Orthodontics, Anchorage Planning
Assessment of Decision Support System Software in Extraction and Anchorage Planning Among Adult Patients Using Computer Algorithm
It was introduced in dentistry to be used in innovative research and development in addition to facilitating the decision in complicated cases and ensure high patient care quality.
- Trial name
- NCT05348109
- Testing
- Well finished cases
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Post-operative Pain
Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
- Trial name
- NCT01229449
- Testing
- Ibuprofen/acetaminophen, Ibuprofen/acetaminophen (higher dose), Nurofen Plus®
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Reckitt Benckiser LLC
Anesthesia, Local
PDL Anesthesia Versus Local Infiltration
The literature concerning the success and pain scores of PDL injection technique compared with other techniques remains controversial; whereas some studies found no significant difference in pain scores between local infiltration…
- Trial name
- PDL (NCT03173898)
- Testing
- PDL anesthesia versus local infiltration
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Facial Pain
Capsaicin to Control Pain Following Third Molar Extraction
This study will test the effectiveness of the drug capsaicin in controlling pain after third molar (wisdom tooth) extraction. Capsaicin, the ingredient in chili peppers that makes them "hot," belongs to a class of drugs called…
- Trial name
- NCT00008476
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Root Canal Infection
Radicular Dentin Remaining, Risk of Perforation and Canal Transportation in Manual Versus Rotary Instrumentation in Primary Molars
Background: Root canal preparation techniques using manual instruments have found to be time-consuming and may lead to iatrogenic errors such as ledging, zipping, canal transportation, and apical blockage.
- Trial name
- NCT04793308
- Testing
- Endodontic files
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Dental Anxiety
Effectiveness of Aromatherapy and Digital Anesthesia in Managing Dental Anxiety and Pain in Children
The goal of this clinical study is to learn whether aromatherapy and digital anesthesia are effective in reducing dental anxiety and pain during tooth extraction in children.
- Conditions
- Pain, Dental Anxiety, Tooth Extraction
- Trial name
- NCT07547371
- Testing
- Traditional Local Anesthesia (Conventional Syringe), Aromatherapy (Lavender or Orange Essential Oil), Digital Local Anesthesia (SleeperOne 5)
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arzu Pınar Erdem
Pain
Multiple Dose Dental Pain Study Of Ibuprofen Extended Release
The study hypothesis is that single and multiple doses of ibuprofen 600 mg ER caplets provide analgesic efficacy superior to placebo over 12-hour dosing intervals.
- Trial name
- NCT01266161
- Testing
- Ibuprofen 600 mg ER
- Where
- 2 sites in United States
- Volunteers
- 106 people
- Sponsor
- Pfizer