Clinical trials: Tear Film
Juvenile Systemic Lupus Erythematosus
AS-OCT Study of Cornea and Tear Film Parameters in Juvenile SLE Patients
The aim of thie study to assess tear film parameters such as tear meniscus height (TMH), tear meniscus area (TMA), and tear meniscus depth (TMD).
- Trial name
- NCT05015465
- Testing
- Anterior Segment OCT
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Minia University
Non-Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy New Vessels on Disc
The Effect of Combination of Vitamin A, Vitamin E, Sodium Hyaluronate 0.15% Eye Drop Compared With Sodium Hyaluronate 0.1% Eye Drop to Tear Film Stability and Conjunctival Goblet Cells Density in Patient With Non-Proliferative Diabetic Retinopathy (NPDR), and Proliferative Diabetic Retinopathy (PDR)
Commonly know that one of the complications caused by Diabetes Mellitus (DM) is microangiopathy. Microangiopathy in the long term may lead to neuropathy of the corneal nerves.
- Conditions
- Non-Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy New Vessels on Disc, Dry Eye Syndromes
- Trial name
- NCT04000789
- Testing
- Sodium Hyaluronate, Vitamin A, Vitamin E
- Volunteers
- 96 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Wound, Rupture
Study Comparing the Polyurethane Films and Sugarcane Biopolymer Used as Dressings
The aim of this study is validate the use of biopolymer from sugar cane molasses film (POLYSHAFT®) a product developed in Experimental Station research laboratories (UFRPE) comparing to polyurethane film, or similar, used as a…
- Conditions
- Wound, Rupture, Surgery, Cesarean Section
- Trial name
- NCT02531828
- Testing
- Application of dressings for surgical correction., POLYSHAFT®
- Where
- Brazil
- Volunteers
- 141 people
- Sponsor
- Polisa - Biopolímeros para Saúde
White Blood Cells
Study of the Cell Response in the Tear Film After Overnight Contact Lens Wear
The purpose of this study was to count and analyze the white blood cells in tear samples collected from study participants following sleep.
- Trial name
- CORNWALL (NCT01379768)
- Testing
- Lotrafilcon A contact lens, Lotrafilcon B contact lens, Clear Care Cleaning and Disinfection Solution
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CIBA VISION
Dry Eye
Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry Eye
Investigate the effect of 3% Diquafosol on tear film and vision-related quality of life in dry eye patients wearing orthokeratology lenses(OK lens), and to provide reference for clinical treatment.This prospective, open label…
- Trial name
- NCT06537349
- Testing
- 3% Diquafosol tetrasodium
- Volunteers
- 30 people
- Sponsor
- He Eye Hospital
Eye Disease
Analysis of Human Tear Proteins in Children
The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film, and any unique aspects of tears in children.
- Trial name
- NCT00473278
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dry Eye Disease
Assess the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.
Orthokeratology(OK) is currently one of the effective methods for treating myopia, reshaping the corneal epithelium to change refractive power.
- Trial name
- NCT06023108
- Testing
- Orthokeratology, Spectacles
- Where
- China
- Volunteers
- 300 people
- Sponsor
- He Eye Hospital
Tear Film Characteristics
Quantifying Ocular Surface Aberrations After Tear Film Interventions
The CA-800 Corneal Analyzer (Visia Imaging S.R.L., Italy) is a device that can measure small imperfections in the tear film when the eyes are open.
- Trial name
- GAMBIA (NCT06966349)
- Testing
- Systane Complete Preservative-Free, Senofilcon A, Somofilcon A
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Thyroid Eye Disease
AS-OCT of the Cornea in Thyroid Diseases
use the anterior segment optical coherence tomography (AS-OCT) to evaluate the tear meniscus parameters, total corneal thickness (CT), and epithelial thickness in active and inactive thyroid eye diseases (TED) patients and…
- Trial name
- NCT05241626
- Testing
- AS-OCT
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Minia University
Dry Eye
Effect of Intense Pulse Light (IPL) Treatment on Tear Film Osmolarity
Evaluate changes in tear film osmolarity and other DED signs/symptoms following treatment with IPL.
- Trial name
- NCT02992535
- Testing
- Intense Pulse Light Energy delivery (IPL)
- Volunteers
- 60 people
- Sponsor
- Carones Ophthalmology Center