Clinical trials: Teeth; Lesion
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries Extending Into Dentin
Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth
The sample will be, at least, 90 primary molars, randomly distributed into three groups: Group 1: IPC; Group 2: SE; Group 3: SCR.
- Trial name
- Caries_removal (NCT03650647)
- Testing
- Carious dentin removal
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Caries in Children, Tooth Erosion
3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children
This study focuses on assessing dental caries, erosive tooth wear, and fluorosis in primary teeth using a 3D intraoral digital scanner.
- Conditions
- Dental Caries in Children, Tooth Erosion, Fluorosis, Dental, Dental Caries
- Trial name
- NCT06829550
- Testing
- indirect- 3D digital scanning
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Indiana University
White Spot Lesions
One Year Clinical Evaluation of White Spot Lesions Treated With Newly Introduced Resin Modified Glass Ionomer in Comparison to Resin Infiltration in Anterior Teeth Split Mouth Technique
The aim of this study is to evaluate the addition of new technology of resin modified glass-ionomer in comparison to resin infiltration in treating post-orthodontic white spot lesions; both applies into the same patient's mouth…
- Trial name
- NCT02912741
- Testing
- Vanish xt Extended Contact Varnish, resin infiltration
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cairo University
Demineralisation, White Spot Lesions
A Trial of Tooth Mousse to Remineralise Post-orthodontic Treatment White Spot Lesions
Fixed dental braces are associated with the risk of developing White Spot Lesions (WSLs), which appear as white chalky marks on the teeth.
- Conditions
- Demineralisation, White Spot Lesions, Orthodontic Treatment
- Trial name
- NCT01344473
- Testing
- Tooth Mousse creme (Casein Phosphopeptide)(RECALDENT)
- Where
- 2 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Dundee
Dental Caries
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.
- Trial name
- NCT04446390
- Testing
- Himalaya complete care toothpaste, colgate cavity protection
- Where
- 2 sites in Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apical Periodontitis
Lesion Healing After Regenerative Endodontic Treatment
Endodontics involves various therapeutic interventions for diagnosing, preventing, and managing pulpal and periradicular pathologies.
- Trial name
- NCT06843850
- Testing
- regenerative endodontics
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Primary Teeth, Pulp Necrosis
Success of Lesion Sterilization and Tissue Repair Therapy
This study aimed to assess the clinical and radiographic success of lesion sterilization and tissue repair (LSTR) therapy with different antibiotic combinations, focusing on evaluating whether the alternative combination of…
- Conditions
- Primary Teeth, Pulp Necrosis, Pulpitis - Irreversible
- Trial name
- NCT06818578
- Testing
- Lesion Sterilization and Tissue Repair Therapy, Different Antibiotic Combinations
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Evaluation of the Efficacy of SPR-G Barrier Coat Versus Fluoride Varnish Versus MI Paste in the Treatment of Early White Spot Lesions in Pediatric Patients
In-Vivo randomized clinical trial to compare between the clinical performance of fluoride varnish versus MI paste (CPP_ACP) and the PRG- Barrier coat material concerning enamel remineralization, arrest of active early lesions…
- Trial name
- NCT05202821
- Testing
- PRG Barrier Coat, Fluoride varnish, MI paste
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Pulpal Necrosis
Triple Antibiotic Paste vs Simvastatin for Lesion Sterilization and Tissue Repair in Primary Molars.
This randomized, double-blinded, parallel-controlled clinical trial aims to compare the effectiveness of Triple Antibiotic Paste (TAP) and Simvastatin in Lesion Sterilization and Tissue Repair (LSTR) of primary molars with pulp…
- Trial name
- LSTR (NCT07264842)
- Testing
- Lesion Sterilization and Tissue Repair using Simvastatin., Lesion Sterilization and Tissue Repair using Triple Antibiotic Paste.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Tooth Decay
Preventive Treatment Approach of Early Caries Lesions With Contemporary Methods of Remineralization
The purpose of this study is to evaluate 1. the additional therapeutic benefit of Curodont Repair for the treatment early occlusal carious lesions on permanent teeth in children compared fluoride varnish alone 2.
- Trial name
- NCT03780270
- Testing
- Fluoride Varnish, Curodont Repair, Curodont Protect
- Volunteers
- 90 people
- Sponsor
- University Dentistry Clinical Center of Kosovo
White Spot Lesions on Smooth Surface of Tooth
The Effectiveness of the Self-Assembling Peptide P11-4 in the Remineralization of Enamel Carious White Spot Lesions
This is three-arm Randomized Controlled Trial. The main goal is to evaluate the effectiveness of self-assembling peptide P11-4 (SAP P11-4) in the remineralization of enamel carious white spot lesions.
- Trial name
- WSL-Curodont (NCT07664046)
- Testing
- Self-assembling peptide P11-4, Fluoride varnish
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Medical University of Warsaw
White Spot Lesion of Tooth
Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth
This study is a randomized controlled trial involving 118 children ages between 4 and 5 years to assess the remineralization effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions in primary…
- Trial name
- NCT03526276
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Deep Caries Lesion of Primary Teeth, Dental Pulp Diseases
Caries Location and Its Effect on the Success Rate of Indirect Pulp Treatment in Primary Molars
The following study will be created to evaluate how the location of caries affects the effectiveness of indirect pulp treatment in primary molars. aiding in the development of evidence-based recommendations for pediatric dentists.
- Conditions
- Deep Caries Lesion of Primary Teeth, Dental Pulp Diseases, Deep Proximal Caries, Deep Occlusal Caries
- Trial name
- NCT06675058
- Testing
- Indirect Pulp Treatment
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dental Caries
Decision Aids for the Management of Suspicious Occlusal Caries Lesions
The study will determine whether clinicians who use a diagnostic device treat suspicious occlusal carious lesions (SOCL) surgically more often, with the same frequency, or less frequently, than dentists not relying on a…
- Trial name
- SOCL (NCT02340767)
- Testing
- Spectra Device, DIAGNOdent
- Where
- 6 sites in United States
- Volunteers
- 3,085 people, healthy volunteers welcome
- Sponsor
- The National Dental Practice-Based Research Network
Dental Caries, White Spot Lesion
A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome
The goal of this clinical trial is to compare the treatment effect of vitamin D supplementation and topical fluorides in the population having vitamin D deficiency and Initial Carious Lesions (ICL) on the progression of ICL in…
- Conditions
- Dental Caries, White Spot Lesion, Initial Caries, Incipient Enamel Caries
- Trial name
- Incipient (NCT06172764)
- Testing
- Vitamin D supplements along with behavioral modification, Topical fluoride application and Vitamin D supplements along with behavioral modification, Topical fluoride application along with behavioral modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dental White Spots
Enamel Damages Following De-bracketing From Infiltrated Surfaces
Demineralisation and white-spot caries often occures during MB treatment. While resin infiltration has been proved to stop progression of enamel demineralisation, there is still a paucity of information in the literature…
- Trial name
- NCT02359318
- Testing
- Resin infiltration, Bonding and debonding of brackets.
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
White Spot Lesion of Tooth, Tooth Color
Toothpastes With Different Contents and Tooth Color
This study aims to investigate the color tone and fluorescence changes that may occur during fixed orthodontic treatment with brackets in patients' teeth using toothpaste with different properties.
- Conditions
- White Spot Lesion of Tooth, Tooth Color, Dentistry, Orthodontic Appliances, Fixed
- Trial name
- NCT06833970
- Testing
- Colgate use, Curaprox use, ROCS use
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Taner OZTURK, DDS, MS