Clinical trials: Temperature Change, Body
Aortic Dissection, Aortic Diseases
Antibiotic Prophylaxis for TEVAR
The infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of…
- Conditions
- Aortic Dissection, Aortic Diseases, Aortic Aneurysm, Thoracic, Coarctation of Aorta
- Trial name
- NCT05405790
- Testing
- thoracic endovascular aortic repair
- Where
- China
- Volunteers
- 457 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Cervical Intraepithelial Neoplasia
Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion
The purpose of this trial is to determine whether SWETZ (Straight Wire Excision of Transformation Zone) is a superior alternative to LLETZ cone (Large Loop Excision of Transformation Zone cone biopsy) in the management of…
- Trial name
- NCT00995020
- Testing
- Straight Wire Excision of Transformation Zone, Large Loop Excision of Transformation Zone (cone biopsy)
- Where
- 2 sites in Brazil
- Volunteers
- 103 people
- Sponsor
- Oswaldo Cruz Foundation
Fever
The Effect of Prophylactic Antipyretics on Immune Responses and Fever After 2014-2015 and 2015-2016 Inactivated Influenza Vaccine
This study aims to conduct a double-blind, placebo-controlled study to assess the effect of prophylactic antipyretics on the immune responses and rates of fever after inactivated influenza vaccine (IIV) in children 6 through 47…
- Trial name
- NCT02212990
- Testing
- Acetaminophen Arm, Ibuprofen Arm
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Duke University
Infant, Newborn, Hypoxia, Brain
Late Hypothermia for Hypoxic-Ischemic Encephalopathy
This study is a randomized, placebo-controlled, clinical trial to evaluate whether induced whole-body hypothermia initiated between 6-24 hours of age and continued for 96 hours in infants ≥ 36 weeks gestational age with…
- Conditions
- Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic
- Trial name
- NCT00614744
- Testing
- Hypothermia, Normothermic Control
- Where
- 22 sites in United States
- Volunteers
- 168 people
- Sponsor
- NICHD Neonatal Research Network
Fever
Host-based Immunoassay for Differentiating Bacterial From Viral Infections (Post-marketing Study of ImmunoXpert™ - SPIRIT Study)
This is a retrospective external field study of a novel in vitro diagnostic (IVD) assay (ImmunoXpert™). The study will involve reviewing the medical charts of about 4500 pediatric patients that were tested using ImmunoXpert™ as…
- Trial name
- NCT03075111
- Testing
- ImmunoXpert
- Where
- 2 sites in Israel
- Volunteers
- 3,000 people
- Sponsor
- MeMed Diagnostics Ltd.
Neuromuscular Disease, Malignant Hyperthermia
The Prevalence of RYR1-related Disease
The skeletal muscle ryanodine receptor (RYR1) gene encodes an important calcium channel in skeletal muscle, with an important role in muscle contraction. Mutations (i.e.
- Conditions
- Neuromuscular Disease, Malignant Hyperthermia, Congenital Myopathy, Multiminicore Disease
- Trial name
- NCT06791369
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- King's College London
Hypothermia
Neonatal Warming to Prevent Hypothermia
Researchers are proposing a pilot randomized controlled trial evaluating the benefit of immediately warming preterm babies using a warming mattress and a plastic wrap, while delaying clamping the umbilical cord at the time of…
- Trial name
- NCT04827394
- Testing
- Neonatal warming mattress, Sterile polyethylene wrap
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Oklahoma
Body Temperature Changes, Fever
Tympanic Thermometer Study
The goal of this study is to collect febrile, healthy, and in some instances cold temperature data from human subjects ranging from newborns to geriatrics. This data will be used to develop a new thermometer.
- Trial name
- NCT06556628
- Testing
- Increased Body Temperatures
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Asthma, Wheezing
Acetaminophen Versus Ibuprofen in Children With Asthma
The Acetaminophen Versus Ibuprofen in Children with Asthma study will test the primary hypothesis that in preschool children 12-59 months of age with persistent asthma on standardized asthma therapy, the number of asthma…
- Trial name
- AVICA (NCT01606319)
- Testing
- Acetaminophen, Ibuprofen
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- Milton S. Hershey Medical Center
Hypothermia, Accidental, Defibrillation
Defibrillation in Accidental Hypothermia
Hypothermia (core temperature ≤35°C) is a frequent and life-threatening complication after mountain accidents, near-drowning, and intoxications, and can provoke arrhythmia, reduced cardiac contractility, and cardiac arrest.
- Trial name
- NCT06131892
- Testing
- Defibrillation
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- University Hospital, Geneva
Fever, Anaemia
Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies
Malaria remains a major cause of morbidity and mortality particularly among children < 5 years in Uganda. Due to inaccessibility many children die before they reach the health facility.
- Conditions
- Fever, Anaemia, Malaria
- Trial name
- NCT00259142
- Testing
- Chloroquine, sulphadoxine-pyrimethamine
- Where
- Uganda
- Volunteers
- 1,314 people
- Sponsor
- DBL -Institute for Health Research and Development
Hypothermia
Hypothermia in the Trauma Patient - When do Trauma Patients Get Cold?
The purpose of this study is to analyze changes in core body- and skin temperature during pre-hospital and early in-hospital treatment of multi-traumatized patients.
- Trial name
- NCT01006837
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Fever, Febrile Illness
Fever and Febrile Support for Parents and Carers of Children 2016
To assess the suitability and user-friendliness of an information leaflet for parents on management of fever and febrile illness in children.
- Trial name
- NCT02903342
- Testing
- Leaflet
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College Cork
Fever
Validation of the Masimo INVSENSOR00063 in Febrile and Afebrile Subejcts
This is a prospective, non-randomized data collection study to evaluate the performance of the Masimo INVSENSOR00063 in obtaining temperature measurements.
- Trial name
- NCT05787782
- Testing
- Masimo INVSENSOR00063
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Body Temperature Changes
Radiant Warmer Trial
The purpose of this study is to compare three radiant warmer beds that contain different computer heating software and different bed styles.
- Trial name
- NCT01011855
- Testing
- GEHC IWS 4400 & Giraffe Warmer beds
- Sponsor
- GE Healthcare
Dengue Fever, Fever
Prospective Surveillance of Febrile Illness for Dengue-Endemic Areas in Asia
The purpose of this study is to detect acute febrile episodes and dengue infection in five Asian countries, to assess dengue seroprevalence, and to assess surveillance infrastructure at investigational sites in anticipation of a…
- Trial name
- NCT01218906
- Where
- 11 sites in Indonesia, Malaysia and 3 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sanofi
Invasive Fungal Disease, Fever and Neutropenia
Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients
The Sponsor hypothesize that Next-generation Sequencing (NGS) can identify fungal pathogens, is more accurate than other noninvasive options and can report fungal genomic load.
- Conditions
- Invasive Fungal Disease, Fever and Neutropenia, Invasive Fungal Infections, Immunocompromised
- Trial name
- NCT03262584
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Karius, Inc.
Hypothermia
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604447
- Testing
- Hypothermia prevention with plastic bag, Hypothermia prevention without plastic bag
- Where
- Zambia
- Volunteers
- 118 people
- Sponsor
- University of Alabama at Birmingham
Magnetic Field Exposure, Temperature Change, Body
Increase in Temperature in Children Undergoing MRI
An increasing number of children undergo Magnetic Resonance Imaging (MRI). In MRI, radio waves and magnetism are used to form images of the body's interior, to diagnose and monitoring diseases in children.
- Conditions
- Magnetic Field Exposure, Temperature Change, Body, Children, Only
- Trial name
- HOT-MR (NCT04317378)
- Testing
- Braun thermoscan /, IRT 6520
- Where
- Denmark
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypothermia
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part II
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604421
- Testing
- Thermoregulation-standard care, Thermoregulation with plastic bag
- Where
- Zambia
- Sponsor
- University of Alabama at Birmingham