Clinical trials: Test
Electroencephalographic Neonatal Seizures
A Study to Test the Pharmacokinetics, Efficacy, and Safety of Brivaracetam in Newborns With Repeated Electroencephalographic Seizures
The purpose of the study is to evaluate the pharmacokinetics (PK) of brivaracetam (BRV) in neonates who have seizures that are not adequately controlled with previous antiepileptic drug (AED) treatment, and to identify the…
- Trial name
- NCT03325439
- Testing
- Brivaracetam (BRV) intravenous (iv), Brivaracetam (BRV) oral
- Where
- 12 sites in Belgium, Czechia and 5 more
- Volunteers
- 9 people
- Sponsor
- UCB Biopharma SRL
Flexible Flatfoot
Foot Posture and Balance in Children With Flexible Flatfeet: Effects of Mud-walk
The study will be a quasi-experimental study with a pre-post study design. 37 children with bilateral flexible flatfeet of age 6-11 years will be recruited by non-probability convenience sampling with pre and post assessment.
- Trial name
- NCT07244172
- Testing
- mud-walk
- Where
- Pakistan
- Volunteers
- 37 people
- Sponsor
- Riphah International University
Cancer
Unusual Toxicity Induced by Radiotherapy
In order to evaluate the physiopathological knowledge of the different pathological manifestations associated with individual radiosensitivity, it seems essential to carry out this pilot study.
- Trial name
- CRYOTOX (NCT03980977)
- Testing
- skin biopsy, tumor biopsy, blood sample
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Institut de Cancérologie de Lorraine
Fever, Malaria
Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar
The purpose of this study is to study the effectiveness of wide scale RDT use at the primary health care level in previously high malaria endemic area during malaria pre-elimination phase for improved targeting of anti-malarial…
- Trial name
- RDTACT (NCT01002066)
- Where
- Tanzania
- Volunteers
- 3,890 people
- Sponsor
- Karolinska University Hospital
HIV, HIV Infections
Evaluating Post-test HIV Counseling Videos for Teens
The design of this randomized controlled trial (RCT) is to test the effectiveness of a post-test behavioral video in educating adolescents about HIV transmission and affecting their intentions to engage in risk-reduction behavior.
- Trial name
- Control (NCT00851539)
- Testing
- Video
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- North Bronx Healthcare Network
Pregnancy
Multicenter Prospective Cumulus Cell Test Study
Performing an additional non invasive oocyte diagnostic test based on cumulus gene expression could improve the outcome of the ART cycle.
- Trial name
- MC_CC-Test (NCT02962466)
- Testing
- CC-Test
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Obesity
Healthy Body Study
Few obesity prevention programs have produced weight gain prevention effects that persist over long-term follow-up and those that have are extremely lengthy, averaging 52 hr in duration, making implementation difficult and…
- Trial name
- NCT02011646
- Testing
- Healthy Weight, Controlled Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Schizophrenia
A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations
Schizophrenia (SCH) is a devastating brain disorder with grave personal, family and social cost. SCH is a complex and heterogeneous (both genetic and clinical) disorder with oligogenetic endowed vulnerability risk of disease…
- Trial name
- SONPOS (NCT01075373)
- Where
- Taiwan
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cystic Fibrosis
Modeling of Chest Physiotherapy Using Impedance Measurements (PHYSIOMOD)
"The usefulness of respiratory physiotherapy and its execution modalities remains highly debated even though reviews of the literature show that respiratory physiotherapy is able to improve the drainage of bronchial secretions…
- Trial name
- PHYSIOMOD (NCT04094441)
- Testing
- chest physiotherapy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Screening, Aortic Aneurysm and Dissection
A Study to Evaluate the Feasibility of Screening Relatives of Patients Affected by Non-Syndromic Thoracic Aortic Diseases
The primary hypothesis is that a tailored programme of genetic and imaging screening of first- and second-degree relatives of patients affected by non-syndromic forms of thoracic aortic diseases will identify individuals at risk…
- Conditions
- Screening, Aortic Aneurysm and Dissection, Genetic Disease
- Trial name
- ReST (NCT03861741)
- Testing
- WES, MRI, TTE
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Colon Cancer, Colorectal Cancer
Does Genetic Susceptibility for Bleeding Affect Quantitative Faecal Immunochemical Test (qFIT) Results?
Quantitative faecal immunochemical testing (qFIT) is used to test for blood within faeces that cannot always be visible. The presence of blood in the stool has been shown to be a finding where there may be a problem within the…
- Trial name
- NCT05329870
- Testing
- SNP array
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Edinburgh
Pulmonary Arterial Hypertension, Pulmonary Hypertension
Pharmacogenomics in Pulmonary Arterial Hypertension
Our goal is to determine clinically in Pulmonary Arterial Hypertension patients if associations exist between the efficacy and toxicity of sitaxsentan, bosentan, and ambrisentan and several gene polymorphisms in several key…
- Conditions
- Pulmonary Arterial Hypertension, Pulmonary Hypertension, PAH WHO Group I
- Trial name
- NCT00593905
- Testing
- Sitaxsentan, Bosentan, Ambrisentan
- Where
- United States
- Sponsor
- West Penn Allegheny Health System
Gastrointestinal Disease, Esophageal Cancer
PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide
The goal of this clinical research study is to use a new breathing test that measures the amount of nitric oxide (NO) you exhale.
- Conditions
- Gastrointestinal Disease, Esophageal Cancer, Lung Cancer
- Trial name
- NCT00867477
- Testing
- Breathing Test, Respiratory Symptoms Questionnaire, Pet Scan
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- M.D. Anderson Cancer Center
Child Development
Testing of Online Version of QAPS
Early evaluation of prewriting skills is important, as prewriting skills set the stage for later learning of the fine motor and visual motor skills needed for writing.
- Trial name
- NCT05905523
- Testing
- Assessing prewriting skills in children
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Virginia Commonwealth University
Non-Suicidal Self Injury, Suicide
Dialectical Behavioral Therapy in Juvenile Justice
Self-injurious thoughts and behaviors (SITBs) are a serious public health concern, particularly for youth involved in the juvenile justice system (JJS), which the Georgia State Juvenile Justice System (GAJJS) intends to address…
- Conditions
- Non-Suicidal Self Injury, Suicide, Self-harm, Emotion Regulation
- Trial name
- DBT-A&JJS (NCT05583279)
- Testing
- Dialetical Behavioral Therapy for Adolescents
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Catholic University of America
Rickettsial Disease
Causes of Fever in Bangladeshi Patients
Background: The clinical features and prevalence of tropical rickettsial illnesses such as murine and scrub typhus in Bangladesh are unknown.
- Trial name
- NCT02339259
- Testing
- Observation
- Where
- Bangladesh
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Friedreich Ataxia
Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia
The primary objective is to evaluate the potential effectiveness of an individualized intensive rehabilitation intervention using the "Prokin 252" stabilometric platform in the treatment of adolescent and adult patients with…
- Trial name
- NCT06692296
- Testing
- Balance training over stabilometric platform, Balance training by means of conventional rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Eugenio Medea
Body Composition, Exercise Test
Identification of Sports Talents in Boxers
This study aims to identify sporting talents by profiling a group of young boxers residing in the State of Mexico using unsupervised machine learning methods.
- Conditions
- Body Composition, Exercise Test, Psychological Well-Being
- Trial name
- NCT06269848
- Where
- Mexico
- Volunteers
- 178 people
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
Nicotine Labeling for E-cigarettes
Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes
Current labels for the nicotine in e-cigarette/vaping products do not sufficiently convey information to the public. The aims of this study include developing and validating two new types of labels for the nicotine in vaping…
- Trial name
- NCT07553585
- Testing
- Updated Labeling
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Yale University
Lower Limb Amputation Knee, Lower Limb Amputation Below Knee (Injury)
Validity and Reliability of The 3-Meter Backward Walk Test in Individuals With Lower Limb Amputation
Clinicians are routinely required to make decisions about fall risk among lower limb prosthesis users. For these decisions, clinicians should use valid, reliable, quantitative, and multidimensional measures of balance test for…
- Trial name
- NCT05095584
- Testing
- 3 meter backward walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tezel Yıldırım Şahan
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