Clinical trials: Test
Cystic Fibrosis
Impact of Discontinuing Chronic Therapies in People With Cystic Fibrosis on Highly Effective CFTR Modulator Therapy
Despite the increasingly common use of cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies in treating CF, it is still largely unknown whether or not other chronic therapies can be safely stopped.
- Trial name
- SIMPLIFY (NCT04378153)
- Where
- 80 sites in United States
- Volunteers
- 987 people
- Sponsor
- Nicole Hamblett
Infections, Rotavirus
A Study to Test 2 Doses of the HRV Vaccine Given With or Without OPV in Healthy Infants in Bangladesh
The main objective of this study is to provide immunogenicity data for GSK Biologicals' HRV vaccine when co-administered with OPV or when given alone (HRV vaccine dose given 15 days after the OPV dose).
- Trial name
- NCT00139334
- Testing
- Rotavirus
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Information About the Knowledge on the Statistical Background of Lung Cancer Screening of Doctors
Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?
This study evaluates whether doctors are familiar with the statistical background of lung cancer screening.
- Trial name
- NCT02542332
- Testing
- With Data
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Otto Wagner Hospital
Bronchiolitis
The ROUTT-B (Reduce Over-Utilized Tests and Treatments in Bronchiolitis) Study
Over-testing and over-treatment costs the US healthcare system hundreds of billions of dollars a year, and has measurable negative impacts on patients' physical, emotional, and financial health making it a significant public…
- Trial name
- ROUTT-B (NCT04302207)
- Testing
- De-implementation Strategy for Bronchiolitis
- Where
- 3 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- University of Colorado, Denver
Food Allergy
Skin Prick Test for the Diagnosis of Food Allergy- a Comparison of Different Commercial Extracts and Raw Food
Immediate food allergy is , sometimes , a life threatening situation . Diagnosis is done by skin prick test with commercial extracts.
- Trial name
- NCT01508299
- Testing
- skin test
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Healthy Children
Learning and Encouragement Effect on 6 Minute Walking Test in Children Between 6 and 12 Years
Evaluation of the learning and encouragement effect on six minutes walking test in children under 12 years
- Trial name
- NCT03276299
- Testing
- six minute walking test
- Where
- Belgium
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Bladder Cancers
Detection of Chromosomal Aberrations in Urine Samples Using Fluorescent in Situ Hybridization (FISH) (UroVysion Test)
The purpose of the study is the identification of chromosomal aberrations in urine samples. The imaging system is intended for diagnostic use as an aid to the pathologist in the detection, counting and classification of UroVysion…
- Trial name
- NCT01264744
- Where
- 3 sites in United States
- Volunteers
- 174 people
- Sponsor
- Applied Spectral Imaging Ltd.
Spastic Cerebral Palsy, Spastic Gait
Effects of Different Time Period of Standing Frame on Spasticity and Gait in Children With Spastic Cerebral Palsy.
Cerebral palsy is a neurological disorder with abnormalities in muscle tone, movement disorders and motor incapability. It attributes to harm to the growing brain.
- Trial name
- NCT05113433
- Testing
- conventional physical therapy, standing frame.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shifa Tameer-e-Millat University
Iron Overload, Hemoglobinopathies
Comparing CGM and OGTT in Relation to Iron Overload Detected by Pancreas T2* MRI in High-Risk Hematology Group
A prospective, observational, comparative study with no intervention.The objective of the study to compare the efficiency of detecting glycemic abnormalities using Continuous Glucose Monitoring (CGMs) versus Oral Glucose…
- Conditions
- Iron Overload, Hemoglobinopathies, Lymphoma, Acute Lymphoblastic Leukemia
- Trial name
- CGMs (NCT03141398)
- Testing
- Continuous Glucose Monitoring (CGM), Oral Glucose Tolerance Test (OGTT), T2* MRI of the Pancreas
- Sponsor
- Hamad Medical Corporation
Mucopolysaccharidoses
Assessment of Factors That Affected Respiratory Parameters in Mucopolysaccharidoses Patients
Respiratory system affects in mucopolysaccharidosis (MPS) disease. Respiratory system symptoms are seen in almost every MPS patients and respiratory failure is one of the most common causes of death in this population.
- Trial name
- NCT04491747
- Testing
- functional capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Rectal Cancer
Expression of Molecular Markers Before and After Neo-adjuvant Chemoradiotherapy in Rectal Cancer
The purpose of this study is to determine whether markers on tumor tissue may be an indicator for good response to neoadjuvant chemoradiotherapy in patients with rectal cancer.
- Trial name
- NCT00835055
- Where
- Switzerland
- Sponsor
- St. Claraspital AG
Hygiene
Dermacyd PH_DETINLYN Sweet Flower (Lactic Acid) - Safety
To prove the safety of the gynaecological formulation in normal conditions of use.
- Trial name
- NCT00785148
- Testing
- Dermacyd PH_DETINLYN Sweet Flower (Lactic Acid)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi
Immunodeficiencies
Novel Testing Procedures
The purpose of this study is to evaluate a novel screening test to detect patients with primary immunodeficiencies(PIDs). The investigators plan to use information gained from this study in order to advance the field of clinical…
- Trial name
- NCT01793506
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Pancreatic Exocrine Insufficiency
The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
- Trial name
- DETECTION (NCT05980221)
- Testing
- Metabolomics, 13C MTGT
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Vision Disparity
Are There Different Objective Fixation Disparity Values for Two Different Test Paradigms
In optometry, binocular coordination is measured subjectively. The result is subjective fixation disparity. In research different experiments have proven, that subjective and objective fixation disparity are different.
- Trial name
- NCT02735278
- Testing
- different test paradigms
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts Northwestern Switzerland
Diabetes in Cystic Fibrosis Patients
Determination of the Predictive Factors in the Reversibility or the Aggravation in the Disorders of the Glucose Metabolism in Cystic Fibrosis Patients
For some years, the investigators observe an increase of the arisen of diabetes in cystic fibrosis patients However, this diabetes may be reversible. The investigators speak about " Cystic fibrosis related diabetes.".
- Trial name
- DIAMUCO (NCT01072708)
- Testing
- Prospective cohort with an annual follow-up
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Hospices Civils de Lyon
HIV, Sexually Transmitted Infections
Peer-Delivered HIV Self-Testing, STI Self-Sampling and PrEP for Transgender Women in Uganda
Transgender women (TGW) are at high risk for HIV infection, and are an important, under-researched population in sub-Saharan Africa. Globally, HIV acquisition risk among TGW is 13 times higher than other adults aged 15-49 years.
- Conditions
- HIV, Sexually Transmitted Infections, PrEP, Transgender Women
- Trial name
- NCT04328025
- Testing
- Peer-delivered HIV self-testing, STI self-sampling and PrEP
- Where
- Uganda
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Makerere University
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Pulmonary Artery Hypertension
Assessing the Repeatability of NT-proBNP Testing Using Laboratory and Point of Care Testing in PAH
The purpose of this study is to examine N-terminal pro brain natriuretic peptide (NT-proBNP) and brain natriuretic peptide (BNP) biomarkers in a number of different settings including assessing the repeatability of laboratory and…
- Trial name
- REPEAT-PAH (NCT05421949)
- Testing
- Exercise group
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Autistic Disorder
Field Test of Motivity.Net Software for Data Collection During Behavioral Interventions
This is a study funded by a Phase II SBIR to build and test the feasibility of a new software prototype for delivering evidence-based behavioral therapy treatment for autism.
- Trial name
- NCT03919721
- Testing
- Applied Behavioral Analysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Experiad LLC
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