Clinical trials: The Cardiac Function
STEMI
ReModeling in ST-elevation myocARrdial Infarction: a Comparison of Left VEntricuLar Functions in Long-term Follow-up Among STEMI Patients
Patients diagnosed with STEMI who underwent pPCI were included in this study. The investigators collected comprehensive data on each patient's status, including laboratory findings such as NT-proBNP, troponin levels, and…
- Trial name
- MARVEL (NCT07041840)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Pisa
Atherosclerosis, Coronary Disease
Study of the Interaction Between the Cells Lining Blood Vessels and Angiotensin-Converting Enzyme
The walls of blood vessels are lined by flat cells that are responsible for releasing substance(s) that control the activity of the blood vessel. These cells are referred to as the endothelium of the blood vessel.
- Trial name
- NCT00001461
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Duchenne Muscular Dystrophy, Cardiomyopathies
The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular Dystrophy
Purpose This cardiac dysfunction in patients with Duchenne muscular dystrophy is associated with minor cardiac damage as indicated by elevation of plasma cardiac troponin I (cTnI).
- Trial name
- NCT00606775
- Testing
- Carvedilol
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Suzuka Hospital
Apnea, Bradycardia
MRSOPA-Drills to Improve Mask Ventilation in the Delivery Room
Establishing breathing after birth is vital for survival and long-term health of premature babies. 10% of all preterm babies fail to breathe after birth and require help with breathing.
- Trial name
- MRSOPA (NCT02375230)
- Testing
- Control group, MR SOPA
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Coronary Artery Spasm, Hypertension
The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication
Autonomic nerve function is involved in both blood pressure (BP) regulation and the pathogenesis of coronary artery spasm(CAS), but few studies have been published about the relationship between CAS and effect of BP lowering…
- Trial name
- NCT01882790
- Where
- 3 sites in South Korea
- Volunteers
- 1,933 people
- Sponsor
- Korea University
Heart Defects, Congenital, Pediatrics
CHAMP App Cardiac Study and Repository
This is a multi-site research study with an optional research repository that will consist of clinically derived data and photographic or video images of patients in the home setting with complex health conditions to evaluate the…
- Trial name
- CHAMP (NCT06034392)
- Testing
- CHAMP App
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Lori Erickson
Physiological Changes in Deliberate Apnea
Evaluating the Influence of Apnea on Cardiac Function Using Cardiac Magnetic Resonance Imaging.
Former studies revealed a distinct pattern of changes in circulation during deliberate apnea. Blood pressure rises significantly often accompanied by bradycardia.
- Trial name
- NCT02280226
- Testing
- magnetic resonance imaging (MRI)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Coronary Artery Disease
Endoscopic Saphenous Vein Harvest for Coronary Artery Bypass Grafting
Although the long saphenous vein remains the most commonly used conduit in coronary revascularization, traditional open vein harvest may lead to significantly impaired wound healing and post-operative pain.
- Trial name
- NCT00712192
- Testing
- coronary artery bypass grafting
- Volunteers
- 34 people
- Sponsor
- Far Eastern Memorial Hospital
Congenital Heart Disease, Acute Kidney Injury
Effects of Anesthetic Techniques on Renal Function
This study evaluates Different effects of two anesthetic techniques on renal function during the perioperative period of cardiac surgery in children.
- Trial name
- NCT04030481
- Testing
- inhalation anesthesia, Total intravenous anesthesia
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Brain Concussion, Mild Traumatic Brain Injury
A Study on the Effect of Mindfulness-based Yoga on Youth With Persistent Concussion Symptoms
Mild traumatic brain injury (mTBI), also known as concussion, is of great concern in the youth population, with incidences of injury steadily increasing within the past few years.
- Trial name
- NCT03217695
- Testing
- Mindfulness-based Yoga Arm
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Persistent Atrial Fibrillation
Effects of Different Surgical Methods for Persistent Atrial Fibrillation Combined With the Application of Statin Drugs on Left Atrial Function
A total of 164 patients with persistent atrial fibrillation, who are planned to undergo treatment with cryoballoon ablation, will be randomly allocated into two groups.
- Trial name
- NCT03700307
- Testing
- Cryoballoon ablation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- The Second Hospital of Hebei Medical University
COVID-19 Pandemic, Dyspnea; Cardiac
Covid-19 Infection and Long-term Cardiovascular Symptoms
From the registry of professor Kojuri clinic , those with Covid-19 infection were selected and was contacted and asked about the cardiovascular symptoms, 1 year after the covid infection
- Conditions
- COVID-19 Pandemic, Dyspnea; Cardiac, Chest Syndrome, Functional Cardiac Disorder
- Trial name
- NCT05715879
- Testing
- covid infection, admission to hispital
- Where
- Iran
- Volunteers
- 879 people
- Sponsor
- Shiraz University of Medical Sciences
Bilateral Pleural Effusion
Impact of Large-Volume Pleural Effusions on Heart Function
The physiologic basis for relief from dyspnea after therapeutic thoracentesis remains poorly understood. Improvement of the heart and lung function may contribute to the dyspnea relief.
- Trial name
- TTE (NCT02548221)
- Testing
- transthoracic echocardiogram
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Bronchopulmonary Dysplasia, Right Ventricular Dysfunction
Right vEntricular Function Prediction mOdel to Identify pReterm infanTs With Early BronchoPulmonary Dysplasia.
Short title REPORT-BPD feasibility study Design A mixed methods observational cohort feasibility study Study Setting Neonatal Intensive Care Unit at University Hospitals Plymouth NHS Trust Aim To explore the feasibility of…
- Conditions
- Bronchopulmonary Dysplasia, Right Ventricular Dysfunction, In the Perinatal Period
- Trial name
- REPORT-BPD (NCT05235399)
- Testing
- Echo scans
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University Hospital Plymouth NHS Trust
Congestive Heart Failure
Safety and Efficacy Study of Carvedilol to Treat Children With Congestive Heart Failure
The purpose of this study is to determine whether a new medicine, called carvedilol, improves symptoms and heart function in children who have congestive heart failure (diminished function of their heart muscle that pumps blood…
- Trial name
- NCT00052026
- Testing
- carvedilol
- Where
- 21 sites in United States
- Volunteers
- 161 people
- Sponsor
- Shaddy, Robert, M.D.
Hepatitis
the Possible Effect of the Antiviral Inhibitors for Treatment of Hepatitis C Virus Infection in Cardiac Function
It has been known for many years that the heart and the liver are intimately related. There is a mutual interaction between the function of the heart and the liver and a broad spectrum of acute and chronic entities that affect…
- Trial name
- NCT03166943
- Testing
- Systolic function by echocardiography, Diastolic function by echocardiography
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Hypotension and Shock, Hypoperfusion
Non-invasive Objective Assessment of Hemodynamics in Preterm Neonates
Study type: Prospective Observational trial Study design: Longitudinal Population: Preterm newborns <32 weeks gestational age Hypothesis: The inclusion of non-invasive physiological measures of cardiac output, peripheral…
- Conditions
- Hypotension and Shock, Hypoperfusion, Hemodynamic Instability, Intraventricular Hemorrhage
- Trial name
- NOAH (NCT04538079)
- Testing
- Multimodal objective non-invasive Monitoring
- Where
- Ireland
- Volunteers
- 56 people
- Sponsor
- University College Cork
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
ACS (Acute Coronary Syndrome), HF - Heart Failure
A Clinical Study on the Effect of Cardiopulmonary Function and Quality of Life in Patients With Acute Coronary Syndrome Complicated by Heart Failure by "Lying-Sitting-Standing" Sequential Baduanjin
This study investigates the effects of a sequential "lying-sitting-standing" Baduanjin intervention on patients with acute coronary syndrome complicated by heart failure.
- Trial name
- NCT07486791
- Testing
- standard treatment and routine rehabilitation nursing guidance, "Lying-Sitting-Standing" Sequential Baduanjin
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Xiling Qi
Chronic Kidney Disease, Pediatric
The Cardiovascular Comorbidity in Children With Chronic Kidney Disease Study
Children and adolescents with chronic kidney disease (CKD) are at high risk for cardiovascular (CV) morbidity and mortality. Recent studies suggest that pediatric patients with even moderately impaired kidney function may be…
- Conditions
- Chronic Kidney Disease, Pediatric, Cardiovascular Disease
- Trial name
- 4C (NCT01046448)
- Where
- 50 sites in Austria, Belgium and 13 more
- Volunteers
- 650 people
- Sponsor
- Heidelberg University