Clinical trials: The Effectiveness of Anesthesia
164 Boys for Hypospadias Surgery Under General Anesthesia With Caudal Block
Caudal Dexmedetomidine Analgesia in Pediatrics .
Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia. This prospective double blinded randomized comparative study is designed to evaluate the analgesic…
- Trial name
- NCT03791879
- Testing
- Caudal dexamedatomidine analgesia
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Local Anesthesia
Buffered Anesthetic Solution in the Treatment of Mandibular Primary Molars
In a prospective, randomized clinical trial, triple-blind, split-mouth study, 40 children aged between 7 to 10 with bilateral mandibular primary molars were diagnosed with pulpitis.
- Trial name
- NCT05793905
- Testing
- Buffered lidocaine in inferior alveolar nerve block injection, lidocaine 2% in inferior alveolar nerve block injection
- Where
- Syria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Damascus University
General Anesthetic
HSK3486 (Cipepofol) Injectable Emulsion for Induction of General Anesthesia in Pediatric Subjects Undergoing Elective Surgery
This multicenter, randomized, double-blinded, propofol-controlled Phase 3b study enrolls pediatric subjects aged 3-17 years undergoing elective surgery with endotracheal intubation.
- Trial name
- NCT07510945
- Testing
- HSK3486, propofol
- Volunteers
- 400 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Anxiety
Effectiveness of Mobile Applications During the Administration of Local Anesthesia in Pediatric Dentistry
To evaluate the mobile games' effect on patient acceptance of local anesthesia and decreasing dental pain and anxiety levels in pediatric patients.
- Trial name
- NCT04731181
- Testing
- mobile application (little lovely dentist).
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pediatric Anesthesia, Low Level Laser Theraphy
Efficacy of Low Level Laser Therapy on İnjection Pain
The purpose of this study was to compare the pain during needle insertion and injection in supraperiosteal anesthesia with either topical anesthesia (control) or LLTT (experimental).
- Trial name
- NCT04243811
- Testing
- Diode Laser, topical anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Okan University
Pain
Pain Management Following Dental Treatment Under General Anesthesia
The main goal of this study is to test the efficacy of postoperative pain management for cases undergoing extractions of primary teeth under GA using a validated measure.
- Trial name
- NCT06574516
- Testing
- Ibuprofen 200 mg, paracetamol
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
This Study Aims to Evaluate the Effectiveness of the INJEX Device in Administering Local Anesthesia
Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia.
Local anesthesia is a common and essential procedure for the majority of dental treatments. The most frequently used method of administration is needle injection.
- Trial name
- NCT07426523
- Testing
- INJEX 30, Traditional syringe
- Where
- Syria
- Volunteers
- 52 people
- Sponsor
- Damascus University
Healthy
Efficacy of Recruitment Maneuver in Pediatric Patients Under General Anesthesia
During general anesthesia lung collapses and atelectasis occurs. Preservation of atelectasis can cause pulmonary disfunction. The goal of safe anesthesia is to protect the lungs intraoperatively.
- Trial name
- NCT03745443
- Testing
- increase and decrease positive end-expiratory pressure
- Where
- Serbia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Ambulatory Surgical Procedures
Effect of Dexmedetomidine on the Prevention of Emergence Agitation in Children Undergoing Day Surgery
Emergence agitation/delirium (EA/ED) is a common complication in pediatric surgery patients, which increases the risk of developing postoperative airway obstruction and respiratory depression.
- Trial name
- NCT03262090
- Testing
- 0.2ug/kg dexmedetomidine, 0.4ug/kg dexmedetomidine, 0.6ug/kg dexmedetomidine
- Where
- China
- Volunteers
- 389 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Catheter Site Pain, Pain, Acute
A Study to Evaluate the Efficacy and Safety of Zingo in Chinese Children
The purpose of the study is to evaluate the efficacy and safety of Zingo in treating pain associated with venipunture and peripheral venous cannulation.
- Conditions
- Catheter Site Pain, Pain, Acute, Anesthesia, Local
- Trial name
- NCT03653260
- Testing
- Lidocaine (Zingo)
- Where
- China
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Soft Tissue Anesthesia (Numbness)
Safety and Efficacy Study of NV-101 in Dental Patients
The purpose of this study was: to determine if NV-101 accelerates recovery from numbness compared to placebo to evaluate safety of NV-101
- Trial name
- NCT00154167
- Testing
- NV-101 (phentolamine mesylate solution)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Novalar Pharmaceuticals, Inc.
Bidirectional Endoscopy
ED90 of Remimazolam Anesthesia Induction in Painless Bidirectional Endoscopy in Children
Exploring the ED90 of remimazolam in pediatric bidirectional endoscopy at different age groups.
- Trial name
- ED90 (NCT06121609)
- Testing
- Remimazolam
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Tongji Hospital
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Appendectomy, Pediatric
The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia
This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery.
- Trial name
- NCT07088900
- Testing
- caudal block using dexmedetomidine with bupivacaine, caudal block with bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Regional Anesthesia Morbidity, Post Operative Pain
THE EFFICIENCY OF FASCIAL PLANE BLOCKS IN BARIATRIC SURGERY
Bariatric surgery effectively produces weight loss and reduces obesity-related comorbidities. Although it is mostly performed with minimally invasive techniques, the patients may still suffer from moderate-to-severe pain…
- Conditions
- Regional Anesthesia Morbidity, Post Operative Pain, Bariatric Surgery Candidate
- Trial name
- NCT05284695
- Testing
- Bariatric surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Pain Management, Endoscopy, Gastrointestinal
Construction and Effectiveness Evaluation of Painless Digestive Endoscopy Mode Led by Anesthesia Nurses Under the Guidance of Anesthesiologists
The purpose is to verify the effectiveness and safety of the painless digestive endoscopy mode led by anesthesia nurses under the guidance of anesthesiologists.
- Trial name
- NCT06712264
- Where
- China
- Volunteers
- 18,000 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Anesthesia Intubation Complication
Muscle Relaxants on Efficacy of LMA Insertion
The use of laryngeal mask airway (LMA) is increasing in pediatric anesthesia because it provides lesser direct mechanical stimulation of the airway due to being placed above the larynx.
- Trial name
- LMA_MR (NCT03487003)
- Testing
- rocuronium, saline
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Daegu Catholic University Medical Center
Tonsillectomy
Effects of Virtual Reality on Pre-Operative Anxiety and Induction of Anesthesia in Children and Adolescents
Pain and anxiety have a direct correlation. Patients who experience anxiety are more susceptible to feeling pain, and patients who experience pain are more likely to have a component of anxiety associated with their pain.
- Trial name
- NCT03239743
- Testing
- Virtual Reality, Midazolam
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Valley Anesthesiology Consultants
Anesthesia, Local
Diode Laser on the Reversal of Inferior Alveolar Nerve Block Anesthesia in Children
Inevitable problems were reported following the injection of local anesthesia in pediatric dental procedures, which can last until the elimination of soft tissue anesthesia.
- Trial name
- NCT05648981
- Testing
- Inferior Alveolar Nerve Block administration with laser irradiation, Inferior Alveolar Nerve Block administration
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Hams Hamed Abdelrahman
Molar Incisor Hypomineralisation
Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH
Aims: Comparison of injection pain with lidocaine and articaine in children with MIH . Comparison of the efficacy of lidocaine and articaine during treatment of MIH molars.
- Trial name
- NCT05200884
- Testing
- Lidocaine 2%, Articaine 4%
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University