Clinical trials: Therapeutic Community
Community-acquired Pneumonia, Child, Only
Stopping Pneumonia Antibiotherapy Regimen Early
The hypothesis for this trial is that an antibiotic strategy for the management of non-severe community-acquired alveolar pneumonia in children aged 3 to 59 months, including amoxicillin 80-100 mg/kg/day for at least 3 days in…
- Trial name
- SPARE (NCT06291012)
- Testing
- Quick response: Amoxicillin for 3 days, Delayed response: Amoxicillin for 5 days, Quick response: Amoxicillin for 5 days
- Where
- France
- Volunteers
- 1,100 people
- Sponsor
- University Hospital, Montpellier
Malaria, Pneumonia
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
This study is to assess the value of incorporating a malaria RDT based strategy in HMM. The primary activity of the study wil be a two armed cluster randomised trial in two study sites in Uganda, one in Ghana and one in Burkina…
- Trial name
- NCT00720811
- Testing
- Artemether-lumefantrine combination, amoxycillin, paracetamol
- Where
- 4 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 6,456 people
- Sponsor
- Mbarara University of Science and Technology
Pediatric Obesity, Pediatric Overweight
BasketballRx: Game Changing Health
The goal of this study is to learn if BasketballRx, a basketball and health program, works well for children and teens who are overweight or have obesity.
- Conditions
- Pediatric Obesity, Pediatric Overweight, Anxiety, Depression Disorders
- Trial name
- NCT07778433
- Testing
- BasketballRx
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
HIV Infections, Adherence, Medication
Technology Based Community Health Nursing to Improve Combination Anti-Retroviral Therapy (cART) Adherence and Virologic Suppression in Youth Living With HIV
Human immunodeficiency virus (HIV) infection has disproportionately persisted as a public health threat to adolescents and young adults (AYA) from minority communities in the United States.
- Trial name
- Tech2Check (NCT03600103)
- Testing
- Tech2Check
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Johns Hopkins University
Lymphatic Filariasis, Helminth Infection
Twice Yearly Treatment for the Control of LF
The Global Program for the Elimination of Lymphatic Filariasis (GPELF) has been in operation sing the year 2000, with the aim of eliminating the disease by the year 2020, following 5-6 rounds of effective annual Mass Drug…
- Trial name
- NCT03036059
- Testing
- 400 μg/kg Ivermectin + 400 mg Albendazole
- Where
- Ghana
- Volunteers
- 1,462 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
HIV Infections
Integrated Treatment of Marijuana Abuse for HIV+ Youth
This is an exploratory study that will adapt and test a combined cognitive behavioral treatment and contingency management intervention for alcohol and/or marijuana abuse for use in HIV-infected adolescents.
- Trial name
- NCT00683488
- Testing
- Focus Group, First Intervention Trial, Intervention Trial 2
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Malnutrition, Severe, Malnutrition, Child
Expanding Coverage of Severe Acute Malnutrition (SAM) Treatment in Kenya
Child wasting is a type of malnutrition which occurs when a child becomes too thin. This medical condition increases the risk of becoming sick or dying.
- Conditions
- Acute Malnutrition, Severe, Malnutrition, Child, Wasting
- Trial name
- R-SWITCH (NCT06441305)
- Testing
- SWITCH intervention package
- Where
- Kenya
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Asthma
Randomised Controlled Trial of a Multi-faceted Community-based Intervention to Improve Asthma in Children
The objectives of this trials are to demonstrate, in children with poorly controlled asthma, that an intervention to increase the awareness and the impact of poor asthma control among parents and physicians of affected children…
- Trial name
- NCT00238888
- Testing
- asthma control awareness, Usual care
- Where
- Canada
- Volunteers
- 298 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Parkinson's Disease
Medication Review in Patients on Anti-parkinson Therapy
To identify patients within the community taking anti-parkinson medications in whom the diagnosis of Parkinson's disease is incorrect and to supervise and clinically monitor the withdrawal of anti-parkinson medications in this…
- Trial name
- PDCom (NCT00443768)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- South Glasgow University Hospitals NHS Trust
Acquired Immunodeficiency Syndrome, Stress Disorders, Post-Traumatic
HIV Prevention and Care of Psychological Trauma in Vulnerable Rwandan Youth
The investigators propose a prospective single arm pilot cohort study of 100 youth (ages 15-25) to evaluate the feasibility of this project.
- Trial name
- NCT01401335
- Testing
- Questionnaires
- Where
- 2 sites in United States, Rwanda
- Volunteers
- 120 people
- Sponsor
- Stanford University
Heat Illness, Heat Stroke
Heat Emergency Awareness and Treatment (HEAT)
Investigators propose an intervention trial of a comprehensive education and treatment bundle designed to reduce morbidity and mortality associated with heat-related illness for low resource settings.
- Conditions
- Heat Illness, Heat Stroke, Heat Exhaustion, Heat Exposure
- Trial name
- HEAT (NCT03513315)
- Testing
- Implementation of Community-based Home Heat Bundle, Regular Community Healthcare provision
- Where
- 2 sites in Pakistan
- Volunteers
- 16,973 people
- Sponsor
- Johns Hopkins University
Behavior Problems
Community Development Teams to Scale-Up Multidimensional Treatment Foster Care (MTFC) in California
The effects of using Community Development Teams to increase the number of counties that successfully implement and sustain Multidimensional Treatment Foster Care programs is studied in a randomized trial in 40 California…
- Trial name
- NCT00880126
- Testing
- Community Development Teams
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Center for Research to Practice
Lymphatic Filariases
Prevalence Studies After Triple Drug Therapy for Lymphatic Filariasis
This study will assess the impact of 2-drug (DA) or 3-drug (IDA) regimens on lymphatic filariasis infection parameters in communities.
- Trial name
- NCT03352206
- Testing
- 2 drug dose - DA, 3 drug dose - IDA
- Where
- 5 sites in Fiji, Haiti and 3 more
- Volunteers
- 20,092 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV
Leveraging Pharmacy Technicians to Advance the Reach of Modern Antiretroviral Therapy (PHARM ART) in Community Clinics
Long-acting injectable HIV medication is an important new innovation in HIV treatment, but complex delivery logistics have resulted in limited access for people with HIV (PWH).
- Trial name
- PHARM ART (NCT07553949)
- Testing
- Pharmacy-technician based model
- Volunteers
- 465 people
- Sponsor
- University of Chicago
Health Behavior, Health Care Utilization
COVID-19: Healthy Oregon (Oregon Saludable): Together We Can (Juntos Podemos) Phase II
The global SARS-CoV-2 pandemic that causes the severe respiratory illness COVID-19 is the worst health crisis that the United States has faced in a century.
- Trial name
- OSJP (NCT05082935)
- Testing
- Phase II Promotores de Salud, Phase I Promotores de Salud Outreach
- Where
- United States
- Volunteers
- 1,463 people
- Sponsor
- University of Oregon
Atrial Fibrillation
AIHEMAF - P "An Innovative Healthcare Model for AF Patients"
Non-profit observational study on the role of the community pharmacist and "the pharmacy of services" in the case management of patients suffering from atrial fibrillation and being treated with new generation oral anticoagulants
- Trial name
- AIHEMAF - P (NCT05086991)
- Testing
- Follow up
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Farmacia La Regina s.r.l.
Marasmus
Effectiveness of Safe Drinking Water in Treatment of Severe Acute Malnutrition (Pakistan)
This study builds evidence on the importance of using safe drinking water during the nutritional treatment of children affected by Severe Acute Malnutrition (SAM).
- Trial name
- NCT02751476
- Testing
- Point of Use (PoU) water treatment flocculent disinfectant., Point of Use (PoU) water treatment chlorine disinfectant, Point of Use (PoU) ceramic water filter
- Volunteers
- 820 people
- Sponsor
- Action Contre la Faim
Childhood Obesity
Community-based Program to Treat Childhood Obesity
This study will evaluate the effectiveness of a comprehensive community based program on reducing excess weight in children and teens. This study will recruit 150 participants between the ages of 6-12 and 13-17.
- Trial name
- NCT01374646
- Testing
- JOIN Intervention
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- UnitedHealth Group
Attention Deficit Hyperactivity Disorder
STAND Community Trial
The proposed study evaluates the effectiveness of a family-based psychosocial treatment program for teens with ADHD (Supporting Teens' Academic Needs Daily; STAND) developed to be delivered in community settings.
- Trial name
- STAND (NCT02694939)
- Testing
- STAND (Behavior Therapy + Motivational Interviewing), Usual Care
- Where
- United States
- Volunteers
- 278 people
- Sponsor
- Florida International University
Patient Compliance
Human Papilloma Viruses (HPV) Vaccine Adherence Community Clinic Study
There has been very limited research that has looked at electronic reminders (text messages) and its effectiveness in adherence to vaccination among low-income minority populations.
- Trial name
- NCT01908517
- Testing
- HPV Vaccine Electronic Reminders
- Where
- 2 sites in United States
- Volunteers
- 522 people, healthy volunteers welcome
- Sponsor
- East Carolina University