Clinical trials: Thermogenesis
Obesity & Overweight
Postprandial Thermogenesis in Obese Adolescents: Effect of Weight Loss
The prevention and management of pediatric obesity require a thorough understanding and consideration of the various components of energy balance (i.e., intake and expenditure) and their interactions.
- Trial name
- TEFAL (NCT07400159)
- Testing
- Anthropometric measurements, Body composition assessment, Leeds Foods Preference Questionnaire
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Emile Roux
Overweight, Obesity
Role of Dietary Protein on Satiety, Food Intake and Thermic Effect of Food
Objectives: To determine the effect of protein content of familiar breakfast meals on subjective appetite, food intake (FI), glycemic response and Thermic Effect of Food (TEF) in normal weight (NW) and overweight (OW)/obese (OB)…
- Trial name
- NCT02200796
- Testing
- Control Meal, Low Protein Meal, Moderate Protein Meal
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Non-exercise Activity Thermogenesis
Non-Exercise Activity Thermogenesis (NEAT) in Children
Non-exercise activity thermogenesis (NEAT) is the energy expended engaging in daily activities such as maintenance of posture, fidgeting, and other activities not specifically designated as "exercise." A growing body of evidence…
- Trial name
- NCT00315172
- Testing
- Non-Exercise Activity Thermogenesis (NEAT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cold Induced Thermogenesis
An Examination of Brown Adipose Tissue and Energy Expenditure in Infants
Excess fetal adipose tissue growth during intrauterine development increases future obesity risk. Development of brown adipose tissue, a highly thermogenic organ in utero, may affect postnatal energy expenditure, thus influencing…
- Trial name
- Born2Burn (NCT05517967)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Pennington Biomedical Research Center
Obesity and Overweight, Leptin Resistance
Reprogramming Energy Homeostasis in Overweight Individuals Via Exercise, Cognitive, and Social Training
The RESILIENT project is a clinical trial investigating leptin sensitivity in both children and adults with overweight or obesity.
- Conditions
- Obesity and Overweight, Leptin Resistance, Childhood Obesity
- Trial name
- Resilient (NCT06931730)
- Testing
- Nutritional Intervention, Physical Activity training, Cognitive training
- Where
- 2 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Childhood Obesity, Childhood Obstructive Sleep Apnea
Co-existent Obstructive Sleep Apnea (OSA) and Obesity: Finding Non-exercise Activity Thermogenesis (NEAT) Targets for Intervention
Rationale: Obesity is an increasing childhood epidemic in Canada. Obstructive sleep apnea (OSA) is a complication of obesity which causes cardiovascular disease, reduced quality of life, and premature death.
- Trial name
- NCT00854334
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Katz, Sherri Lynne, M.D.
Obesity (Disorder)
JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program With or Without Semaglutide in Adolescents With Obesity
The Joule MARS study is a single center, randomized, open label clinical trial aiming to explore the metabolic adaptations that occur in response to weight management in adolescents with obesity.
- Trial name
- JOULE-MARS (NCT06852391)
- Testing
- Semaglutide Pen Injector, Behavioural Lifestyle Program (BLP)
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- McMaster University
Obesity
Water Induced Thermogenesis in Obese Children
Drinking water is largely advocated for obesity prevention and management. Recent studies have suggested that water has a thermogenic effect, this has not been examined in children.
- Trial name
- NCT00794469
- Testing
- Water
- Where
- Israel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Neonatal Hypothermia, Brown Adipose Tissue
Investigation of the Mechanisms of the Tendency to Hypothermia in Newborns and Premature Neonates
Newborns have thermoregulatory mechanisms that differ from those of adults. Instead of producing heat through shivering, newborns primarily rely on non-shivering thermogenesis by the brown adipose tissue.
- Conditions
- Neonatal Hypothermia, Brown Adipose Tissue, Preterm and Term Infants, Neonate
- Trial name
- NCT06803069
- Where
- 2 sites in Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Obesity (Disorder)
Postprandial Thermogenesis in Obese Adolescents: Effect of Meal Calorie Content
The prevention and management of pediatric obesity require a thorough understanding and consideration of the different components of energy balance (i.e., intake and expenditure) and their interactions.
- Trial name
- TEFAO (NCT07233174)
- Testing
- Energy expenditure and energy substrates, Food sensations, Liking & Wanting
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Emile Roux
Phenylketonuria (PKU)
Body Composition, Energy Intake and Expenditure in People With Phenylketonuria
This will be case-control study investigating whether dietary intake and components of energy expenditure such as Basal metabolic rate (BMR), physical activity energy expenditure (PAEE) and diet induce thermogenesis (DIT) are…
- Trial name
- NCT03309345
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Glasgow