Clinical trials: Third Molar Extraction
Pain, Post-Operative Pain
Ibuprofen Extended-Release Dental Pain Study
The purpose of this study is to evaluate the efficacy and safety of multiple doses of Ibuprofen 600 mg Extended-Release Tablets in a study of dental pain following extraction of third molar teeth.
- Conditions
- Pain, Post-Operative Pain, Third Molar Extraction
- Trial name
- NCT00707057
- Testing
- Ibuprofen 600 mg Extended-Release Tablets
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- SCOLR Pharma, Inc.
Impacted Third Molar Tooth
Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.
The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction.
- Trial name
- NCT06262945
- Testing
- Diagnoses, traditional osteotomies, platelet rich fibrin
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beste Erismen
Impacted Third Molar Tooth
Epidemiological Study on the Surgical Removal of Third Molars
The aim of this study is to get a clear view on current practice of surgical third molar removal in Belgium and the association with morbidity and complications.
- Trial name
- NCT02481700
- Testing
- Third molar removal
- Volunteers
- 6,010 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Impacted Third Molar Tooth
Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus
The present study was to evaluate the effect of topical Arnica and MPSP application with respect to visual analogue scale (VAS) scores, maximal interincisal opening (MIO) and edema values after mandibular impacted third molar…
- Trial name
- NCT04534426
- Testing
- : Arnica montana, Mucopolysaccharide polysulfate, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pain
Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain
This study will evaluate how genetic makeup contributes to the variation in people regarding their sensitivity to and experience of pain.
- Trial name
- NCT00115752
- Testing
- Valdecoxib, COX Inhibitor
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Impacted Mandibular Third Molar Extraction
Piezo-surgery Technique and Intramuscular Dexamethasone Injection to Reduce Postoperative Pain After Impacted Mandibular Third Molar Surgery
The purpose of my study is to test the effect of using piezosurgery and dexamethasone injection in the surgical extraction of impacted mandibular third molars, on Postoperative Pain.
- Trial name
- NCT04889781
- Testing
- Dexamethasone injection, Piezosurgery, Conventional Rotatory instruments
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Military Healthcare - Oral and Maxillofacial Surgery Department
Photodynamic Therapy, Third Molar Extraction
The Effect of Photodynamic Therapy on Post-extraction Third Molar
The extraction of lower third molars is one of the most frequent procedures in oral surgery. For this reason, the extraction of these teeth generally requires a surgical approach involving the elevation of a mucoperiosteal flap…
- Conditions
- Photodynamic Therapy, Third Molar Extraction, Antimicrobial Photodynamic Therapy
- Trial name
- NCT06964178
- Testing
- Experimental: antimicrobial photodynamic therapy (aPDT) after extraction of third molar
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Third Molar Impaction
The Effect of Different Treatment Modalities of Class II Malocclusion on Upper Third Molars.
What is the effect of the different treatment modalities (distalization versus upper premolar extraction) of class II malocclusion on the position, inclination and incidence of impaction of the upper third molars?
- Trial name
- NCT06098885
- Testing
- extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class II Malocclusion
Effect of Maxillary Third Molar Extraction vs. Non-extraction on Distalization of First Molars in a Group of Adolescent Patients
There is a scarcity in literature regarding the influence of maxillary third molar on distalization . This study aimed to compare the influence of unerupted maxillary third molars and their extraction on the bilateral…
- Trial name
- NCT05647720
- Testing
- Distalization combined with upper third molars extraction, Distalization without upper third molars extraction
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Class II Malocclusion
Effect of Upper Third Molar Extraction on Distalization Carriere Motion Appliance :A Prospective Clinical Study
This clinical study will be directed to compare the effect of presence or absence of third molar on distalization of the upper posterior segment by using carriere motion appliance
- Trial name
- NCT05166928
- Testing
- carriere motion appliance
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Impacted Third Molar Tooth
Extraction of Impacted 3rd Molars, Can Bone Support of the Second Molar be Promoted by a Bio-Oss Graft?
A prospective study examining bilateral 3rd molar extraction, by a split mouth protocol the investigators augment unilaterally and compare periodontal parameters in between.
- Trial name
- NCT02753439
- Testing
- Geistlich Bio Oss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Molar, Third, Wisdom Teeth
Effect of Hilotherm Therapy on Post-operative Pain and Swelling Following Surgical Wisdom Tooth Removal
This study evaluates the efficacy of Hilotherm therapy on the incidence of swelling and pain following the surgical removal of lower wisdom teeth.
- Trial name
- NCT02284841
- Testing
- Hilotherm cooling face mask
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Edema, Pain
The Impact of Arnica Montana Following the Surgical Extraction of Impacted Third Molars
Aim: The aim of this study is to evaluate the action of the homeopathic plant Arnica Montana on postoperative edema, pain and trismus after surgical extraction of impacted wisdom teeth.
- Conditions
- Edema, Pain, Trismus
- Trial name
- NCT06193720
- Testing
- Arnica montana
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Oral Surgery
The Effect of Platelet-rich Fibrin on Clinical and Patient-centered Outcomes of Third Molar Extractions
The fear of oral surgeries is mostly dedicated to pain and swelling in the following days. It is not surprising, that it is of high interest to do anything to reduce these consequences.
- Trial name
- PRF (NCT05089812)
- Testing
- Third-molar extraction using platelet-rich fibrin as a filling of the alveolus
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Pain, Oral Surgery
Pulsed Electromagnetic Fields for Postoperative Pain: a Linical Trial in Humans
This randomized clinical trial was designed to assess the clinical efficacy of Pulsed electromagnetic field PEMF delivered with a wearable device in terms of postoperative pain and quality of healing after mandibular third molar…
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT02273999
- Testing
- RecoveryRx™
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Tooth Disease, Piezoelectric Technique
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars
- Conditions
- Tooth Disease, Piezoelectric Technique, Tooth Impacted, Tooth Extraction Status Nos
- Trial name
- Germectomy (NCT06778590)
- Testing
- Piezoelectric technique in third molar germectomy, Traditional technique in third molar germectomy
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Orthodontic Treatment Via Premolar Extraction
Effect of Extraction Versus Non-extraction Orthodontic Treatment on the Third Molars
What is the effect of extraction orthodontic treatment in comparison to non- extraction treatment on the position, inclination and incidence of impaction of the third molars?
- Trial name
- NCT04857658
- Testing
- extraction orthodontic treatment plan
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Fixed-dose Combination of Oxycodone [OXIcodona] + IbuproFEN in Pain Relief After Third Molar Extraction
A clinical, multicenter, randomized, parallel-group, double-blind, double-dummy, comparative study of non-inferiority. ⚠️Study will only be conducted in research centers in Brazil (please do not send e-mail if your center is…
- Trial name
- OXIFEN (NCT05081102)
- Testing
- FDC of oxycodone 5 mg/ibuprofen 400 mg, Tylex
- Where
- Brazil
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Pain, Postoperative, Substance Use
iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery
This is a clinical trial that will evaluate the feasibility and acceptability of a virtual brief program for adolescents and young adults undergoing wisdom tooth extraction and their parents.
- Trial name
- iPAWS (NCT07731295)
- Testing
- iPAWS, Educational Materials
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brown University