Clinical trials: Thoracic Injuries
Stable Angina Pectoris
Prevalence and Prognostic Value of Unrecognized Myocardial Injury in Stable Coronary Artery Disease (PUMI)
This study includes patients with stable coronary artery disease without previously known myocardial infarction, and investigates the prevalence of clinically unrecognized myocardial damage and its prognostic implication.
- Trial name
- PUMI (NCT01257282)
- Where
- 6 sites in Sweden
- Volunteers
- 275 people
- Sponsor
- Uppsala University
Cardiac Arrest
OPALS Critical Care Sub-Studies
The purpose of the study is to evaluate the incremental benefit of a full advanced life support EMS program on the outcomes of chest pain, respiratory and major trauma patients.
- Trial name
- NCT00212953
- Testing
- Advanced Life Support
- Where
- 11 sites in Canada
- Volunteers
- 21,000 people
- Sponsor
- Ottawa Hospital Research Institute
Trauma Chest, Rib Fracture Multiple
Surgical Stabilization for Rib Fractures
The purpose of this study is to compare the usual care alone to usual care plus early surgical stabilization in adult trauma patients who have been admitted with rib fractures, to evaluate for heterogeneity of treatment effect in…
- Trial name
- SSRF (NCT04081233)
- Testing
- surgical stabilization, Usual care
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- The University of Texas Health Science Center, Houston
Bronchopulmonary Dysplasia
Follow-Up Study of Safety and Efficacy of Pneumostem® in Premature Infants With Bronchopulmonary Dysplasia
This is a long term follow-up study of the open label, single-center, phase I clinical trial to evaluate the safety of Pneumostem® in premature infants with BPD.
- Trial name
- NCT01632475
- Testing
- Pneumostem®
- Where
- 2 sites in South Korea
- Volunteers
- 9 people
- Sponsor
- Samsung Medical Center
Traumatic Thoracic Acute Spinal Cord Injury
The INSPIRE Study: Probable Benefit of the Neuro-Spinal Scaffold for Treatment of AIS A Thoracic Acute Spinal Cord Injury
This is an HDE probable benefit, open-label, non- randomized, single-arm, multicenter study to evaluate the safety and probable benefit of the poly(lactic-co-glycolic acid)-b-poly(L-lysine) Scaffold ("Scaffold") in subjects with…
- Trial name
- NCT02138110
- Testing
- Neuro-Spinal Scaffold
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- InVivo Therapeutics
Blunt Injury of Thorax, Flail Chest
Treatment of Acute, Unstable Chest Wall Injuries
Unstable chest injuries are common in poly trauma patients. They can lead to severe pulmonary restriction, loss of lung volume, difficulty with ventilation and can render the patient to require intubation and mechanical…
- Conditions
- Blunt Injury of Thorax, Flail Chest, Chest Wall Injury Trauma, Rib Fracture
- Trial name
- NCT01367951
- Testing
- Surgical fixation
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- Unity Health Toronto
Pediatric Acute Lung Injury
Pharmacologic Impact on Sedation Assessments
PISA is an ancillary study to the NIH funded clinical RESTORE Trial (U01 HL086622). This study will provide data that may allow for improved dosing recommendations in this critically ill population of children.
- Trial name
- PISA (NCT01105663)
- Testing
- Pharmacokinetic Sampling and pharmacogenetic analysis
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Children's Hospital of Philadelphia
Spine Trauma (Thoracic and Lumbar)
3D Printing in Preoperative Planning in Thoracic and Lumbar Spine Trauma
Case series of 16 patients with lower lumbar or lower thoracic traumatic injuries treated with pedicle screw fixation. Patients were divided into two groups (n≈8 per group).
- Trial name
- NCT07727161
- Testing
- Spine stabilization using CT planning, Spine stabilization using 3D-printed model planning
- Where
- Czechia
- Volunteers
- 16 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Thoracic Outlet Syndrome, Whiplash Injuries
Whiplash-induced Thoracic Outlet Syndrome Treated With Botulinum Toxin.
Whiplash injuries following car accident are common, it has been reported to affect 83% of individuals injured in traffic collisions (Yadla S, 2007).
- Trial name
- NCT05536570
- Testing
- IncobotulinumtoxinA 100 UNT
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- King, David, MD
Aneurysm Thoracic, Dissection of Aorta, Thoracic
TBE Zone 2 PMS in Japan
The goal of this surveillance is to confirm the TBE device's safety and efficacy in patients treated with proximal landing in Zone 2 in the post-marketing period.
- Conditions
- Aneurysm Thoracic, Dissection of Aorta, Thoracic, Trauma
- Trial name
- NCT07049913
- Testing
- Gore® TAG® Thoracic Aortic Branch Stent Graft System
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- W.L.Gore & Associates
Rib Fracture
Comparison of Gray-scale Inverted Rib Series With Conventional Ones in Rib Fracture Detection by Emergency Physicians and Medical Students
There were many studies which examined the availability of inverted gray-scale chest X-ray for increasing the detection of lung nodules.
- Trial name
- NCT02028611
- Volunteers
- 55 people
- Sponsor
- Hanyang University
Chest Trauma Patients
Outcome of Chest Trauma Patients in One Year in Sohag University Hospital
The history of chest trauma is as old as that of man himself. One of the earliest writings about chest trauma is found in the Edwin Smith Surgical Papyrus, written in 3000 bc.
- Trial name
- NCT05960409
- Testing
- chest tube - emergency thoracotomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Chest Trauma
Evaluating Validity of Clinical Criteria for Requesting Chest X-Rays in Trauma Patients
The purpose of this study is to identify the clinical criteria for requesting a chest x-ray in a patient with blunt trauma and its findings such as clinical signs with a high sensitivity could be used in a larger study to codify…
- Trial name
- NCT01134744
- Where
- 2 sites in Iran
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Pain, Side Effects
Comparison of IV PCA and Wound Infusion After Repair of Pectus Excavatum
Postoperative pain management is a major problem after repair of pectus excavatum.Various methods of pain management have been introduced.
- Trial name
- NCT01908491
- Testing
- IV PCA, Continuous wound infusion
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Respiratory Distress, Lung Injury
Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in…
- Trial name
- NCT01939067
- Testing
- Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Lung Injury, Extravascular Lung Water
Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO)
Bedside lung ultrasonography helps to obtain reliable clinical information about lung aeration, that has been categorized by means of the so-called lung ultrasound score (LUS).
- Conditions
- Lung Injury, Extravascular Lung Water, Pulmonary Edema, Acute Respiratory Distress Syndrome
- Trial name
- LUS-PICO (NCT04660448)
- Testing
- Bedside lung ultrasound examination
- Where
- Spain
- Volunteers
- 650 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
Blunt Chest Trauma
The Effect of Virtual Reality on Pulmonary Recovery and Mobility in Patients With Blunt Chest Trauma
Blunt chest trauma comprises over 10% of all trauma patients presenting to emergency departments worldwide and is the most frequent injury in polytrauma patients.
- Trial name
- VIREX PURE (NCT05194176)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Radboud University Medical Center
Respiratory Distress Syndrome in Premature Infant, Non-invasive Ventilation
Open Lung Strategy During Non-Invasive Respiratory Support of Very Preterm Infants in the Delivery Room
The opening and aeration of the lung is critical for a successful transition from fetal to neonatal life. Early nasal CPAP in the delivery room in spontaneously breathing premature babies with a gestational age of 30 weeks or…
- Conditions
- Respiratory Distress Syndrome in Premature Infant, Non-invasive Ventilation, Lung Injury
- Trial name
- OpenCPAP-DR (NCT05031650)
- Testing
- openCPAP, standardCPAP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Dokuz Eylul University
Pneumothorax At Trauma Patients
Chest Ultrasound Versus Chest X-ray with Ct As Gold Standard At Trauma Patients
The goal of this observational study is to learn about the predictive value of the chest ultrasound in detection of pneumothorax at chest trauma patients.
- Trial name
- NCT06699277
- Volunteers
- 100 people
- Sponsor
- Assiut University