Clinical trials: Thoracic Injury
Pneumoconiosis
Potential of Deep Learning in Assessing Pneumoconiosis Depicted on Digital Chest Radiography
Pneumoconiosis is relatively prevalent in low/middle-income countries, and it remains a challenging task to accurately and reliably diagnose pneumoconiosis.
- Trial name
- NCT04963348
- Testing
- convolutional neural networks (CNNs)
- Volunteers
- 1,881 people
- Sponsor
- Peking University Third Hospital
Lung Injury, Preterm Birth
Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).
Premature babies often need help immediately after birth to open their lungs to air, start breathing and keep their hearts beating.
- Trial name
- POLAR (NCT04372953)
- Testing
- Positive End-Expiratory Pressure (PEEP)
- Where
- 27 sites in United States, Australia and 5 more
- Volunteers
- 906 people
- Sponsor
- Murdoch Childrens Research Institute
Lung Injury, Acute, Thoracotomy
Prevention of Lung Edema After Thoracic Surgery
Background : Acute lung injury (ALI) occasionally occurs after pulmonary resection and carries a bad prognosis with a high mortality rate ranging from 20 to 100%. Objectives : 1.
- Conditions
- Lung Injury, Acute, Thoracotomy, Anesthesia, Intensive Care, Surgical
- Trial name
- NCT00498251
- Testing
- inhalation of salbutamol (5 mg), ipratropium
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Chest Trauma, Fluid Balance; Disorder
Chest Trauma :Prediction of Thoracic Injuries Clinically and Radiologically
Trauma is a major cause of morbidity and mortality worldwide. Despite the advent of specialized trauma centers the outcome of patients who sustain major trauma remains disappointing.
- Trial name
- chesttrauma (NCT03686579)
- Testing
- chest trauma
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Traumatic Pneumothorax and Hemothorax
Emergency Small vs Large Tube Thoracostomy in Chest Trauma Patients.
To compare between small sized tube thoracostomy and large sized tube thoracostomy regarding the need for another chest tube for the fear of obstruction (in hemomothorax) or ineffective drainage (in hemothorax, pneumothorax or…
- Trial name
- NCT04863989
- Testing
- tube thoracostomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thoracic Aorta, Thoracic Injuries
TRANSFIX Zenith® Transection Clinical Study
The TRANSFIX study is a clinical trial approved by US FDA to study the safety and effectiveness of the Zenith® TX2® Low Profile Endovascular Graft for treatment of Blunt Thoracic Aortic Injury.
- Conditions
- Thoracic Aorta, Thoracic Injuries, Blunt Injuries
- Trial name
- TRANSFIX (NCT01688050)
- Testing
- Zenith® TX2® Low Profile Endovascular Graft
- Where
- 21 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cook Research Incorporated
Rib Fracture
Comparison of Gray-scale Inverted Rib Series With Conventional Ones in Rib Fracture Detection by Emergency Physicians and Medical Students
There were many studies which examined the availability of inverted gray-scale chest X-ray for increasing the detection of lung nodules.
- Trial name
- NCT02028611
- Volunteers
- 55 people
- Sponsor
- Hanyang University
Infant ALL, Computed Tomography
Comparison of Computertomography Scan, Electrical Impedance Tomography, and Ultrasound of the Lung in Infants
The study focuses on regional lung examination, in particular on the differentiation between collapsed and hyperinflated lung areas.
- Conditions
- Infant ALL, Computed Tomography, Electric Impedance, Ultrasonography
- Trial name
- NCT04989439
- Testing
- Electrical impedance tomography and ultrasonography of the lung
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Lung Injury
Acute Lung Injury After Aortic Valve Surgery
The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery.
- Trial name
- NCT01184313
- Testing
- aortic valve surgery with CPB
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu
Athletic Injuries
The Effect of Thoracic Manipulation on Upper Body Stability in Basketball Athletes
Basketball is the most popular sport in the world and has become even more popular as a result of the attention it has received.
- Trial name
- NCT06410235
- Testing
- Thoracic manipulation and exercise program, exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Sepsis
Biomarkers of Lung Injury in Hyperinflation in the Mechanical Ventilator Versus Manual Hyperinflation
Due to the failure of the respiratory system, many patients admitted to the Intensive Care Units (ICUs) require the institution of invasive mechanical ventilation (MV), aiming at maintaining gas exchange, reversing respiratory…
- Trial name
- NCT03464071
- Testing
- Hyperinflation with mechanical ventilator, Manual hyperinflation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Blunt Chest Trauma
The Effect of Virtual Reality on Pulmonary Recovery and Mobility in Patients With Blunt Chest Trauma
Blunt chest trauma comprises over 10% of all trauma patients presenting to emergency departments worldwide and is the most frequent injury in polytrauma patients.
- Trial name
- VIREX PURE (NCT05194176)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Radboud University Medical Center
Iatrogenic Vessel Injury
Treatment of Patients With Traumatic or Iatrogenic Vessel Injuries
The purpose of this study is to confirm device efficacy and safety of the GORE® VIABAHN® Endoprosthesis (hereafter "VB device") for the treatment of traumatic or iatrogenic vessel injury in thoracic, abdominal, and pelvic…
- Trial name
- NCT05183399
- Testing
- GORE® VIABAHN® Endoprosthesis
- Volunteers
- 30 people
- Sponsor
- W.L.Gore & Associates
Cardiac Arrest
OPALS Critical Care Sub-Studies
The purpose of the study is to evaluate the incremental benefit of a full advanced life support EMS program on the outcomes of chest pain, respiratory and major trauma patients.
- Trial name
- NCT00212953
- Testing
- Advanced Life Support
- Where
- 11 sites in Canada
- Volunteers
- 21,000 people
- Sponsor
- Ottawa Hospital Research Institute
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova
Trauma Chest
Median Sternotomy in Penetrating Cardiac Trauma
The investigators aim to assess role of median sternotomy in penetrating cardiac trauma regarding morbidity and mortality of the patients.
- Trial name
- NCT04917198
- Testing
- median sternotomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Blunt Injury of Thorax
Abg in Blunt Chest Trauma
This study aims to determine the value of ABG measurments in patients with blunt chest trauma and its role in prognosis of different outcomes and the results would aid the emergency physicians to speed up the management and…
- Trial name
- NCT05886946
- Testing
- ABG
- Volunteers
- 150 people
- Sponsor
- Assiut University
Respiratory Failure
Regional Distribution Differences Between Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation
Neurally adjusted ventilatory assist (NAVA) is an FDA approved mode of mechanical ventilation. This mode of ventilation is currently in routine use in adult, pediatric and neonatal intensive care units.
- Trial name
- NCT01504373
- Testing
- Neurally Adjusted Ventilatory Assist (NAVA)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Children's Hospital
Burns, Respiratory Function Impaired
Inspiratory Muscle Training in Children With Chest Burn
8 weeks of inspiratory muscle training combined with a pulmonary rehabilitation program increases respiratory muscle strength, pulmonary function, functional capacity, and quality of life in chest burned children.
- Conditions
- Burns, Respiratory Function Impaired, Children
- Trial name
- chestburn (NCT05603507)
- Testing
- inspiratory muscle training, pulmonary rehabilitation
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Qassim University