Clinical trials: Tics
Tourette Syndrome in Adolescence, Social Adjustment
Board Game Project for Adolescents with Tourette Syndrome
The study aims to investigate the effectiveness of using a board game to improve adolescents' tics, mental health, and interpersonal interactions.
- Conditions
- Tourette Syndrome in Adolescence, Social Adjustment, Psychosocial Functioning
- Trial name
- NCT05566236
- Testing
- board game
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Tourette's Syndrome, Attention Deficit Hyperactivity Disorder
Study of Clonidine on Sleep Architecture in Children With Tourette's Syndrome (TS) and Comorbid ADHD
In the present study, we examine the question "Will day-time aggression in children improve when their night-time sleep is treated with pharmacological intervention (i.e.
- Trial name
- NCT00152750
- Testing
- APO-clonidine
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Tic Disorders
XTics - A Gamified Enhancer of Non-Pharmacological Interventions in Tic Disorders
The investigators developed a neuroscientifically-informed gamified tic-therapy platform. The investigators previously identified tic-triggering elements in movies and video games.
- Trial name
- NCT06348511
- Testing
- XTics
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Tic Disorder
Teen and Adult Tic TMS Study
This project investigates safety, tolerability, and efficacy signals of accelerated continuous theta burst stimulation (cTBS), a form of inhibitory repetitive transcranial magnetic stimulation (rTMS), for patients with Tourette…
- Trial name
- NCT07839377
- Testing
- cTBS (accelerated continuous theta burst stimulation)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Behavior Disorders
Tics in Childern With Acute Deficit Hyper Activity Syndrom
Tics have been defined as sudden, rapid, recurrent, non-rhythmic, stereotyped, involuntary movements or vocalizations. Motor tic can be either simple or complex, depending on whether one or several muscle groups are…
- Trial name
- NCT03817710
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Tourette Syndrome
Response Inhibition in Tourette Syndrome
Tics are the hallmark symptoms in Tourette Syndrome. Patients with Tourette Syndrome have difficulties controlling unwanted movements.
- Trial name
- NCT03628703
- Testing
- Repetitive TMS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Tourette Syndrome
A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder
The primary objective of this study is to evaluate the long-term safety and tolerability of ecopipam tablets in children (greater than or equal to [>=] 6 and less than [<] 12 years of age), adolescents (>=12 and <18 years of…
- Trial name
- NCT06021522
- Testing
- Ecopipam
- Where
- 67 sites in United States, Bulgaria and 6 more
- Volunteers
- 150 people
- Sponsor
- Emalex Biosciences Inc.
Tourette's Syndrome
Optimising Anterior Pallidal Deep Brain Stimulation for Tourette's Syndrome
The motor tics associated with Tourette's syndrome may be reduced with deep brain stimulation of the anterior globus pallidus. The best area within this brain region and the best stimulation device settings are currently unknown.
- Trial name
- NCT02112253
- Testing
- Deep brain stimulator ventral electrode up to 2 mA, Deep brain stimulator ventral electrode up to 3 mA, Deep brain stimulator dorsal electrode up to 2 mA
- Where
- Australia
- Sponsor
- The University of Western Australia
Tics, Tourette Syndrome
CBIT+TMS R33 Phase
Chronic tics are a disabling neuropsychiatric symptom associated with multiple child-onset mental disorders. Chronic tics affect 1-3% of youth 1 and are associated with impaired functioning, emotional and behavioral problems…
- Trial name
- NCT06678737
- Testing
- CBIT +cTBS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Tourette Disorder, Chronic Tic Disorder
Augmentation of Brief Habit Reversal Training With D-cycloserine or Placebo
Expert reviews and practice parameter papers recommend behavior therapy as a first-line intervention for youth with chronic tic disorders (CTDs) with mild-to-moderate tic severity.
- Trial name
- DCS+HRT (NCT02582515)
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Brain Injuries, Wounds and Injuries
Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: A Pilot and Feasibility Study
Trauma is the leading cause of death and disability in children in the United States. The long-term goal of this project is to evaluate the benefits and harms of tranexamic acid (TXA; a drug that stops bleeding) in severely…
- Conditions
- Brain Injuries, Wounds and Injuries, Hemorrhage
- Trial name
- TIC-TOC (NCT02840097)
- Testing
- Tranexamic Acid
- Where
- 4 sites in United States
- Volunteers
- 31 people
- Sponsor
- Daniel Nishijima, MD, MAS
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
Internet-delivered Behaviour Therapy for Children and Adolescents With Tourette's Disorder
The purpose of this trial is to evaluate the clinical efficacy, 12-month durability, and cost-effectiveness of BIP TIC - a therapist-guided and parent-guided internet-delivered behavioural intervention for children and…
- Trial name
- NCT03916055
- Testing
- Exposure and response prevention (ERP), Education on tics
- Where
- Sweden
- Volunteers
- 221 people
- Sponsor
- Karolinska Institutet
Tourette Syndrome
Role of Frontal Cortex in the Pathophysiology of Gilles de la Tourette Syndrome (GTS)
Tourette's syndrome (TS) is a debilitating and severe syndrome whose pathophysiology remains unclear. In order to precise the cortical regions involved in the generation of tics, investigators will realize an electroencephalogram…
- Trial name
- TIC-EEG (NCT03604510)
- Testing
- Electroencephalographic recordings
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Bordeaux
Tics, Tic Disorders
Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder
The goal of this clinical study is to learn more about the timing of tics (sudden, fast movements and sounds that people do and make without meaning to) in people who have multiple tics that have been going on for more than one…
- Conditions
- Tics, Tic Disorders, Vocal Tic, Motor Tic
- Trial name
- PTD (NCT06385535)
- Testing
- Habit Reversal Training (HRT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Tourette Syndrome
Washed Microbiota Transplantation for Tourette's Syndrome
This study aimed to evaluate the efficacy of washed microbiota transplantation in the treatment of Tourette's syndrome (TS).
- Trial name
- WMT (NCT03764748)
- Testing
- Washed Microbiota Transplantation
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Tourette Syndrome
Phase II Double Blind Placebo Controlled Trial of Risperidone in Tourette Syndrome
OBJECTIVES: I. Conduct a randomized, double blind, placebo controlled, parallel study of the atypical neuroleptic risperidone (RIS) in the treatment of children and adults with moderate to severe Tourette Syndrome. II.
- Trial name
- NCT00004393
- Testing
- risperidone
- Volunteers
- 50 people
- Sponsor
- National Center for Research Resources (NCRR)
Dystonia, Drug Induced Dystonia
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
- Conditions
- Dystonia, Drug Induced Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT05317390
- Testing
- DystoniaNet-based diagnosis of isolated dystonia
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Tourette Syndrome
Brain Activity Associated With Tics in Patients With Tourette Syndrome
This study will examine brain activity associated with the involuntary urges or uncontrolled movements, called "tics," experienced by people who have Tourette syndrome (TS).
- Trial name
- NCT00141869
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tourette Syndrome
Multi-site Transcranial Magnetic Stimulation Therapy of the Supplementary Motor Area in Children With Tourette Syndrome
The investigators are investigating the effectiveness of a wearable multisite transcranial magnetic stimulation (mTMS) device that can deliver stimuli at multiple cortical sites simultaneously or sequentially for the treatment of…
- Trial name
- NCT03642951
- Testing
- Active Treatment
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City