Clinical trials: Tissue Damage
Cerebral Palsy
Lower Extremity Functional Training (LIFT) on Gross Motor Function and Gait in Children With Spastic CP
Cerebral Palsy is a developmental disorder caused by damage to the brain before, during or after birth. Spastic Cerebral Palsy is one of the most common types of cerebral Palsy. It affects about 80% of cerebral palsy.
- Trial name
- LIFT (NCT05460936)
- Testing
- Lower Extremity Functional Training, conventional physical therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Spinal Cord Injury/Damage
Body Weight Supported Treadmill Training as Physical Therapy Treatment to Spinal Cord Injury Patients
The purpose of this current prospective study is to assess the effects of body weight support treadmill training (BWSTT) in individuals with spinal cord injury (SCI).
- Trial name
- NCT02031835
- Testing
- BWSTT (3 days a week for maximum of 20 minutes session)
- Where
- Greece
- Volunteers
- 26 people
- Sponsor
- University of Ioannina
Spastic Cerebral Palsy
Evaluation of Multifocal Transcutaneous Electrical Stimulation for Self-treatment Among Children With Cerebral Palsy
The main purpose with this study is to investigate the effectiveness of a garment with integrated electrodes for multifocal transcutaneous electrical stimulation intended for treatment of spasticity in children with cerebral…
- Trial name
- NCT04078321
- Testing
- Mollii ®
- Where
- Sweden
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sormland County Council, Sweden
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Spastic Cerebral Palsy, Motor Activity
Investigation of the Relationship Between Lower and Upper Extremity Selective Motor Control and Sensory Functions in Children With Spastic Cerebral Palsy
Although spasticity, contractures and muscle weakness in children with CP are disorders that can be observed more easily and are more focused and given more importance in evaluation and treatment approaches; Inadequate or loss of…
- Conditions
- Spastic Cerebral Palsy, Motor Activity, Lower Extremity Problem, Upper Extremity Problem
- Trial name
- NCT05696535
- Volunteers
- 100 people
- Sponsor
- Mustafa Kemal University
Suspected Damage to Fetus From Other Disease in the Mother, Affecting Management of Mother, With Delivery, Patient Death or Serious Disability Associated With A Haemolytic Reaction Due to the Administration of ABO-Incompatible Blood or Blood Products
The Use of Lung Ultrasonography in the Delivery Room in Neonates
Lung ultrasonography has become frequently used in neonatal intensive care units because it is a diagnostic, useful, harmless, radiation-free, bedside, reproducible and practical method.
- Trial name
- LUSIN (NCT06314789)
- Testing
- doing lung ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Cerebral Palsy, Temporomandibular Disorder (TMD)
TMJ Dysfunction and Motor Severity in Children With CP
This study aims to examine the function of the temporomandibular joint (TMJ)-the jaw joint-in children with cerebral palsy (CP).
- Trial name
- NCT07043517
- Testing
- RDC/TMD
- Where
- Turkey (Türkiye)
- Volunteers
- 517 people
- Sponsor
- Istanbul Arel University
Cerebral Palsy
PedBot Ankle Rehablitation
The primary objective of the study is to determine engagement with use and adherence to a home exercise program with our PedBotHome ankle rehabilitation device.
- Trial name
- NCT05825508
- Testing
- ankle robot
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's National Research Institute
Cerebral Palsy
Analysis of the Psychometric Properties of Kinematic Parameters of Locomotion Measured by Inertial Measurement Units. Validation in Healthy Children and Children With Cerebral Palsy
Cerebral palsy (CP) is currently one of the major causes of disability in children. The presence of various disorders (muscle stiffness, architectural bone defects, spasticity) leads to a number of functional impacts, including…
- Trial name
- KAPP-IMU anc (NCT06138925)
- Testing
- Analysis of walking, Analysis of running
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Parents of Preterm Infants Born Before 33 Weeks Gestation
PPrime: Parents Views on Diagnosis and Information-giving in Neonatal Care (Pilot Study)
The aim of the pilot study is to explore and identify the issues of concern to parents whose babies have been cared for in a neonatal unit and exposed to imaging, its influence on diagnosis and information-giving process
- Trial name
- PPrime (NCT01055548)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Cerebral Palsy, Spasticity
Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy
The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected…
- Trial name
- Andreani1 (NCT02199015)
- Testing
- Lateral spinal cord surgical implant of electrodes
- Where
- 2 sites in Argentina, Germany
- Volunteers
- 40 people
- Sponsor
- Juan Carlos M. Andreani MD
Cerebral Palsy
Pilot Study on Breathing Exercises and Pulmonary Function in Children With Cerebral Palsy: A Randomized Trial
This pilot study is a randomized controlled trial aimed at investigating the efficacy of protocolized conductive breathing exercises combined with regular air ventilation, in addition to standard care, on various aspects of…
- Trial name
- NCT06840626
- Testing
- Series of breathing exercises
- Where
- Hungary
- Volunteers
- 55 people
- Sponsor
- Semmelweis University
Cerebral Palsy, Hemiplegia
Retrospective Study of Intensive Therapy Pathways in Children With Cerebral Palsy (P'TI-PARCOURS)
This retrospective single-center study aims to describe the care pathways of children with unilateral cerebral palsy (hemiplegia) who participated in intensive therapy programs (COLHEMI and/or Mini-COLHEMI) at the Centre des…
- Trial name
- P'TI-PARCOURS (NCT07683455)
- Testing
- COLHEMI program
- Volunteers
- 75 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Cerebral Palsy
The Effects of Hand-Arm Bimanual Intensive Training (HABIT) in Children With Bilateral Cerebral Palsy
Hand-Arm Bimanual Intensive Training (HABIT) has been shown to result in improvements in hand function and daily functioning of children with unilateral cerebral palsy (CP).
- Trial name
- NCT03474848
- Testing
- HABIT, Conventional Occupational Therapy (OT)
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Cerebral Palsy
Efficacy of a Rehabilitation Program With the Pediatric Exoskeleton ATLAS 2030 in Pediatric Patients With Cerebral Palsy
Cerebral Palsy (CP) is the first cause of motor disability in children worldwide. ATLAS 2030 is a robotic gait exoskeleton designed to rehabilitate children with motor disability.
- Trial name
- NCT05926635
- Testing
- ATLAS 2030
- Where
- 5 sites in Spain
- Volunteers
- 60 people
- Sponsor
- MarsiBionics
Cerebral Palsy, Upper Extremity Paresis
Effectiveness of Armeo Spring Robotic Therapy in the Function of the Upper Limb of Children With Unilateral Spastic Cerebral Palsy Infiltrated With Botulinum Toxin
Background: Unilateral spastic cerebral palsy (CP) generates an impact on daily activities, mainly due to the functional limitation of the affected upper limb.
- Trial name
- NCT04554238
- Testing
- Armeo spring, Occupational Therapy
- Where
- Chile
- Volunteers
- 23 people
- Sponsor
- Sociedad Pro Ayuda del Niño Lisiado
Cerebral Palsy
Erythropoietin Therapy for Children With Cerebral Palsy
This randomized placebo-controlled trial aims to investigate the efficacy and safety of erythropoetin for children with cerebral palsy.
- Trial name
- NCT01650415
- Testing
- Erythropoietin
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Bundang CHA Hospital
Cerebral Palsy
Rhythm and Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy
Cerebral palsy (CP) affects the motor function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them.
- Trial name
- APP-PaC (NCT03440749)
- Testing
- luminous stimuli
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Cerebral Palsy (CP)
Safety and Effectiveness of Bambini Kids Robot-Assisted Gait Training (RAGT) in Children With Cerebral Palsy
Cerebral palsy (CP) is a common cause of gait impairment in children, leading to limitations in mobility and daily activities. Although conventional physical therapy is widely used, it has limitations in delivering consistent and…
- Trial name
- NCT07539389
- Testing
- Exoskeleton, Rehabilitation physical therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Cerebral Palsy (CP), Balance Assessment
Combined Effect of FES And FCT in Cerebral Palsy
To determine the combined effect of functional electrical stimulation and functional circuit training on postural stability, balance, and functional mobility in cerebral palsy
- Trial name
- NCT07573891
- Testing
- Functional Electrical Stimulation and Functional Circuit Training, Control Group
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
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