Clinical trials: Tobacco Dependence
Alcohol Abuse, Cannabis Abuse
Trial of Computerized SBI to Reduce Teen Alcohol Use
The goal of this project is to test the effectiveness of a computer-facilitated alcohol screening and brief intervention (c-ASBI) system for 12- to 18-year-old primary care patients in a multi-site, randomized comparative…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Nicotine Dependence
- Trial name
- NCT01784627
- Testing
- c-ASBI
- Where
- 6 sites in United States
- Sponsor
- Boston Children's Hospital
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency
The Whole Day First Grade Program
This five-year prevention services application is concerned with preventing substance abuse, comorbid mental and behavioral disorders, and school failure.
- Conditions
- Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco
- Trial name
- NCT00257088
- Testing
- whole day first grade program
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- American Institutes for Research
Nicotine Dependence
Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers
The purpose of this study is to evaluate reactions to, and choices to self-administer, cigarette smoke with varying nicotine content among low-frequency, non-dependent adolescent/young adult smokers between the ages of 15-25…
- Trial name
- NicRed (NCT02989038)
- Testing
- Very Low Nicotine Content Cigarettes, Intermediate Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Duke University
Use; Tobacco, Harmful, Alcohol Abuse
Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use
The purpose of the project is to improve adolescent behavioral counseling services in healthcare settings with a new Internet/Intranet-based Motivational Enhancement Therapy (iMET) intervention that targets the use of tobacco…
- Conditions
- Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
- Trial name
- NCT00907309
- Testing
- iMET, iMET/TE
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Boston Children's Hospital
Smoking Cessation; Tobacco Dependence
Characterization of Smoking Habits Patterns in Medical Doctors of a Central Hospital in Portugal - What Has Changed After 15 Years? A Comparative Cross-sectional Study
Abstract: Tobacco dependence remains one of the primary health care concerns worldwide. Attitude of healthcare professionals towards smoking is crucial for any long-term prevention and smoking cessation program.
- Trial name
- NCT02913989
- Testing
- Smoking habits characterization
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Tobacco Use Disorder, Tobacco Dependence
The PROMPT Pilot Study
The PROMPT Pilot Study is a feasibility mixed methods prospective cohort study following principles of community-based participatory action research.
- Conditions
- Tobacco Use Disorder, Tobacco Dependence, Tobacco Use Cessation
- Trial name
- NCT03626064
- Testing
- Smoking Cessation Counselling, Nicotine Replacement Therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Nicotine Dependence
Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers
The purpose of this study is to determine how reducing the level of nicotine in cigarettes may affect adolescent smoking behavior.
- Trial name
- NCT02587312
- Testing
- Very low nicotine content cigarettes, Standard nicotine content cigarettes
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Brown University
Vaping
Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents
Social media based intervention to support teens in their efforts to quit vaping.
- Trial name
- NCT04707911
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Disease, Essential Hypertension
The Northwest Coalition for Primary Care Practice Support
The purpose of this project is to build capacity for quality improvement (QI) in small primary care practices across Washington, Oregon and Idaho by improving risk factors for heart attacks such as blood pressure, cholesterol and…
- Conditions
- Cardiovascular Disease, Essential Hypertension, Nicotine Dependence, Hyperlipidemia
- Trial name
- H2N (NCT02839382)
- Testing
- Coaching, Educational Outreach, Site Visits
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Kaiser Permanente
Tobacco Dependence, Schizophrenia
The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia
Cigarette smoking represents a major health problem for patients suffering from schizophrenia. Compared to the general population, schizophrenic patients are significantly more likely to be addicted to nicotine.
- Trial name
- PSIAARP (NCT00495352)
- Testing
- Hihg-doseNRT, Low-dose NRT, bupropion
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- Yu-Li Hospital
Tobacco Use
Comparing an Opt-out to an opt-in Approach for Smoking Cessation in VA Primary Care Clinics
The investigators propose a Type I hybrid effectiveness/implementation study to evaluate two population-based approaches for increasing use of Quitlines and text messaging at two VA sites.
- Trial name
- NCT03477435
- Testing
- Staff training and academic detailing
- Where
- United States
- Volunteers
- 1,365 people
- Sponsor
- VA Office of Research and Development
Tobacco Dependence Treatment, Lung Cancer Screening
ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening
Lung cancer is the leading cause of cancer-related death among Veterans with 90% of cases attributable to smoking. Lung cancer screening (LCS) combined with smoking cessation saves the most lives.
- Trial name
- ICARE-LCS (NCT06745258)
- Testing
- External Facilitation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Behavior, Nicotine Dependence Tobacco Product
§SMOKE Nicotine and Tobacco Youth Cohort
The §SMOKE Cohort Study aims to improve understanding of tobacco and nicotine use among adolescents and young adults in Denmark.
- Conditions
- Tobacco Use Behavior, Nicotine Dependence Tobacco Product, E-Cigarette Use, Smoking ( Cigarette)
- Trial name
- NCT07910331
- Where
- Denmark
- Volunteers
- 10,000 people
- Sponsor
- University of Southern Denmark
Nicotine Dependence
Extended Cessation Treatment for Teen Smokers
This study is designed to test the efficacy of an extended smoking cessation program for teen smokers. We hypothesize that teen smokers randomized to extended treatment will have a higher abstinence rate at 52 week follow-up than…
- Trial name
- Nicoteens (NCT00459953)
- Testing
- Extended treatment
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Stanford University
Tobacco Dependence
Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking
The purpose of this study is to determine: 1) the short-term clinical efficacy and safety of bupropion for helping adolescent tobacco smokers quit, and 2) The role of withdrawal symptoms in the maintenance of smoking in…
- Trial name
- NCT00248118
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking
Youth Smoking Cessation: Therapy +/- "The Patch"
Reducing tobacco use by adolescents is a national health priority. In recent polls, most adolescent smokers reported having tried unsuccessfully to quit.
- Trial name
- NCT00631020
- Testing
- CBME, Optional NRT
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Drug Abuse, Alcohol Abuse
Trial of Computerized MET for Adolescent Substance Use
The purpose of this study is to test the effects of a computerized, self-directed Motivational Enhancement Therapy program for adolescent substance use (iMET), in comparison to clinician-delivered MET and Treatment As Usual…
- Conditions
- Drug Abuse, Alcohol Abuse, Nicotine Dependence
- Trial name
- NCT01784653
- Testing
- iMET, MET
- Where
- United States
- Sponsor
- Boston Children's Hospital
Cancer, Smoking
Improving Tobacco Treatment Rates for Outpatient Cancer Patients Who Smoke
The main purpose of this research study is to evaluate the effectiveness of "nudges" to clinicians, to patients, or to both in increasing Tobacco Use Treatment Service (TUTS) referral and engagement; and to explore clinician…
- Conditions
- Cancer, Smoking, Tobacco Use, Nicotine Dependence
- Trial name
- SPP1 (NCT04737031)
- Testing
- Clinician Nudge, Patient Nudge
- Where
- 3 sites in United States
- Volunteers
- 2,146 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Asthma, Tobacco
Efficacy of School-Based, Peer-Led Asthma and Smoking Prevention Program on CO1 Levels and Smoking Behavior Among Early Adolescents in Jordan
Study Hypotheses: 1. adolescents in intervention schools who are given Triple A program plus ASP will show more awareness in regards to cigarettee smoking health effects and less nicotine dependencethan those in the control…
- Conditions
- Asthma, Tobacco, Waterpipe, Cigarettes
- Trial name
- TAJPlus (NCT01938976)
- Testing
- TAJ Plus (Adolescent Asthma Action in Jordan) Plus the added class smoke free pledge
- Volunteers
- 815 people
- Sponsor
- University of Technology, Sydney